Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Sarah J Wheelan"'
Autor:
Kimberline Y Gerrick, Elias R Gerrick, Anuj Gupta, Sarah J Wheelan, Srinivasan Yegnasubramanian, Elizabeth M Jaffee
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208602 (2018)
Macrophages are key inflammatory immune cells that display dynamic phenotypes and functions in response to their local microenvironment. Major advances have occurred in understanding the transcriptional, epigenetic, and functional differences in vari
Externí odkaz:
https://doaj.org/article/9fa4135bf2d9403484c5728d477ff71c
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107519 (2014)
Small non-coding RNAs represent RNA species that are not translated to proteins, but which have diverse and broad functional activities in physiological and pathophysiological states. The knowledge of these small RNAs is rapidly expanding in part thr
Externí odkaz:
https://doaj.org/article/0d4857fe81fd4e4498f7b528f518f7b4
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69513 (2013)
Growing evidence suggests that drugs interact with diverse molecular targets mediating both therapeutic and toxic effects. Prediction of these complex interactions from chemical structures alone remains challenging, as compounds with different struct
Externí odkaz:
https://doaj.org/article/51105cb1d7f8493688654b22e4cd4c4f
Autor:
Alexander Favorov, Loris Mularoni, Leslie M Cope, Yulia Medvedeva, Andrey A Mironov, Vsevolod J Makeev, Sarah J Wheelan
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 5, p e1002529 (2012)
We have created a statistically grounded tool for determining the correlation of genomewide data with other datasets or known biological features, intended to guide biological exploration of high-dimensional datasets, rather than providing immediate
Externí odkaz:
https://doaj.org/article/1e76291d7e004e86801a062b9caf6a63
Autor:
Tyler J Creamer, Miranda M Darby, Nuttara Jamonnak, Paul Schaughency, Haiping Hao, Sarah J Wheelan, Jeffry L Corden
Publikováno v:
PLoS Genetics, Vol 7, Iss 10, p e1002329 (2011)
RNA polymerase II synthesizes a diverse set of transcripts including both protein-coding and non-coding RNAs. One major difference between these two classes of transcripts is the mechanism of termination. Messenger RNA transcripts terminate downstrea
Externí odkaz:
https://doaj.org/article/23f12664d9b44cf19a27a4398d502aed
Autor:
Evanthia T. Roussos Torres, Elana J. Fertig, Elizabeth M. Jaffee, Luciane T. Kagohara, Daria A. Gaykalova, Roisin M. Connolly, Vered Stearns, Srinivasan Yegnasubramanian, Min Yu, Sathish Kumar Ganesan, Sarah J. Wheelan, Michael Considine, Alyza Skaist, Anuj Gupta, Ajay Vaghasia, Emma Bigelow, Gaurav Sharma, Emily F. Davis-Marcisak, Valerie H. Narumi, Brian J. Christmas, Edgar Gonzalez, Aaron G. Baugh, Sofi Castanon, Julie K. Jang, Christine I. Rafie, Dimitrios N. Sidiropoulos
Supplementary Data from Entinostat Decreases Immune Suppression to Promote Antitumor Responses in a HER2+ Breast Tumor Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e28169c16cf94af543790c359b314a
https://doi.org/10.1158/2326-6066.22544265.v1
https://doi.org/10.1158/2326-6066.22544265.v1
Autor:
Srinivasan Yegnasubramanian, William G. Nelson, Sarah J. Wheelan, William B. Isaacs, Christina DeStefano Shields, Jianfeng Xu, S. Lilly Zheng, Michael C. Haffner, Jonathan B. Coulter, McKinzie A. Garrison, Alyza Skaist, Ajay Vaghasia, Harshath Gupta, Anuj Gupta, Minh-Tam Pham
Supplementary Figure from Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f74e0f528f0b44e595a4a686d003dd6
https://doi.org/10.1158/1541-7786.22528140
https://doi.org/10.1158/1541-7786.22528140
Autor:
Nishant Agrawal, Patrick K. Ha, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, Carole Fakhry, Shizhang Ling, Michael Considine, Luigi Marchionni, Sarah J. Wheelan, Elana J. Fertig, Rachel Karchin, Noushin Niknafs, Collin Tokheim, Laura D. Wood, Justin A. Bishop, Sian Jones, Mark Sausen, C. Conover Talbot, Eleni M. Rettig
Summary of sequence analysis of adenoid cystic carcinoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49577570400ce0cb89f1b1a24218b07b
https://doi.org/10.1158/1940-6207.22533527.v1
https://doi.org/10.1158/1940-6207.22533527.v1
Autor:
Srinivasan Yegnasubramanian, William G. Nelson, Sarah J. Wheelan, William B. Isaacs, Christina DeStefano Shields, Jianfeng Xu, S. Lilly Zheng, Michael C. Haffner, Jonathan B. Coulter, McKinzie A. Garrison, Alyza Skaist, Ajay Vaghasia, Harshath Gupta, Anuj Gupta, Minh-Tam Pham
Supplementary Data from Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079fa3355e6e7a7e7440b04c149268c2
https://doi.org/10.1158/1541-7786.22528146
https://doi.org/10.1158/1541-7786.22528146
Autor:
Srinivasan Yegnasubramanian, William G. Nelson, Sarah J. Wheelan, William B. Isaacs, Christina DeStefano Shields, Jianfeng Xu, S. Lilly Zheng, Michael C. Haffner, Jonathan B. Coulter, McKinzie A. Garrison, Alyza Skaist, Ajay Vaghasia, Harshath Gupta, Anuj Gupta, Minh-Tam Pham
A limited number of cell lines have fueled the majority of preclinical prostate cancer research, but their genomes remain incompletely characterized. Here, we utilized whole-genome linked-read sequencing for comprehensive characterization of phased m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b27371dbf32222e2f7eb6c3686846b7
https://doi.org/10.1158/1541-7786.c.6545628.v1
https://doi.org/10.1158/1541-7786.c.6545628.v1