Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Sarah J Potter"'
Autor:
Sarah J. Potter, Li Zhang, Michael Kotliar, Yuehong Wu, Caitlin Schafer, Kurtis Stefan, Leandros Boukas, Dima Qu’d, Olaf Bodamer, Brittany N. Simpson, Artem Barski, Andrew W. Lindsley, Hans T. Bjornsson
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Individuals with Kabuki syndrome present with immunodeficiency; however, how pathogenic variants in the gene encoding the histone-modifying enzyme lysine methyltransferase 2D (KMT2D) lead to immune alterations remain poorly understood. Following up o
Externí odkaz:
https://doaj.org/article/cf9678b7fb124e57af5f1be2328c292d
Autor:
Ina N. Eckert, Eliana Ribechini, Katja J. Jarick, Sandra Strozniak, Sarah J. Potter, Andreas Beilhack, Manfred B. Lutz
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Myeloid-derived suppressor cells (MDSCs) represent a major population controlling T cell immune responses. However, little is known about their molecular requirements for homing and T cell interaction to mediate suppression. Here, we investigated the
Externí odkaz:
https://doaj.org/article/5ba9e7cf80b34ca79fd0e3525c67160a
Autor:
Sarah J Potter, Li Zhang, Michael Kotliar, Yuehong Wu, Caitlin Schafer, Kurtis Stefan, Leandros Boukas, Dima Qu’d, Olaf Bodamer, Brittany N Simpson, Artem Barski, Andrew W Lindsley, Hans T Bjornsson
ObjectiveThere is a clinical need to understand how dysregulated thymocyte development, caused by pathogenic variants in the gene encoding the histone-modifying enzyme, lysine methyltransferase 2D (KMT2D), contributes to immune dysfunction, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29c23032151b736380beb719e9be9406
https://doi.org/10.1101/2022.10.04.510662
https://doi.org/10.1101/2022.10.04.510662
Autor:
Tony DeFalco, Sarah J. Potter, Alyna V. Williams, Brittain Waller, Matthew J. Kan, Blanche Capel
Publikováno v:
Cell Reports, Vol 12, Iss 7, Pp 1107-1119 (2015)
The testis produces sperm throughout the male reproductive lifespan by balancing self-renewal and differentiation of spermatogonial stem cells (SSCs). Part of the SSC niche is thought to lie outside the seminiferous tubules of the testis; however, sp
Externí odkaz:
https://doaj.org/article/06fb21d76deb4a30af9a2e6015edffd1
Autor:
Tara Daly, Andrew Lindsley, Christina Hung, Olaf Bodamer, Emanuela Gussoni, Arielle Hall, Tatiana Fontelonga, Caitlin Schafer, Alec Wright, Sarah J. Potter
Publikováno v:
The FASEB Journal. 35
Kabuki syndrome (KS) is a rare genetic disorder caused primarily by mutations in the histone modifier genes KMT2D and KDM6A. The genes have broad temporal and spatial expression in many organs, resulting in complex phenotypes observed in KS patients.
SUMMARYSertoli cells are highly polarized testicular supporting cells that simultaneously nurture progressively maturing germ cells. Proper localization of polarity protein complexes within Sertoli cells, including those responsible for blood-testis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffa82c59450b55f711311dbfc305ab6a
https://doi.org/10.1101/2021.04.26.441535
https://doi.org/10.1101/2021.04.26.441535
Publikováno v:
Cell reports. 37(4)
Sertoli cells are highly polarized testicular supporting cells that simultaneously nurture multiple stages of germ cells during spermatogenesis. Proper localization of polarity protein complexes within Sertoli cells, including those responsible for b
Autor:
Sarah J Potter, Tony DeFalco
Publikováno v:
Reproduction. 153:R151-R162
Male fertility is maintained through intricate cellular and molecular interactions that ensure spermatogonial stem cells (SSCs) proceed in a step-wise differentiation process through spermatogenesis and spermiogenesis to produce sperm. SSCs lie withi
Publikováno v:
Biology of Reproduction. 96:1060-1070
The observation of pups born from recipient and donor mice after ovariectomy followed by ovarian transplant poses the interesting possibility of an extraovarian source of oocytes. However, whether mammalian adult oocytes reside in extragonadal tissue
Inhibiting fibronectin attenuates fibrosis and improves cardiac function in a model of heart failure
Autor:
Jeffery D. Molkentin, Ane M. Salvador, Jiuzhou Huo, Tony DeFalco, Allison E. Schafer, Charles Perkins, Iñigo Valiente-Alandi, Francisco J. Carrillo-Salinas, Sarah J. Potter, Michelle L. Nieman, Tobias G. Schips, Aaron M. Gibson, Pilar Alcaide, John N. Lorenz, Burns C. Blaxall, Michelle A. Sargent
Background: Fibronectin (FN) polymerization is necessary for collagen matrix deposition and is a key contributor to increased abundance of cardiac myofibroblasts (MFs) after cardiac injury. We hypothesized that interfering with FN polymerization or i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9362b2b179c9f92b2cf4e64a7f4e513
https://europepmc.org/articles/PMC6186194/
https://europepmc.org/articles/PMC6186194/