Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sarah J Kaye"'
Autor:
Katharine S Dobb, Sarah J Kaye, Nicola Beckmann, John L Thain, Lubomira Stateva, Mike Birch, Jason D Oliver
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143770 (2015)
Antifungal drugs acting via new mechanisms of action are urgently needed to combat the increasing numbers of severe fungal infections caused by pathogens such as Candida albicans. The phosphopantetheinyl transferase of Aspergillus fumigatus, encoded
Externí odkaz:
https://doaj.org/article/1cd24085abc54adea0bfd6032719577a
Autor:
Jason D Oliver, Sarah J Kaye, Danny Tuckwell, Anna E Johns, Darel A Macdonald, Joanne Livermore, Peter A Warn, Mike Birch, Michael J Bromley
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43559 (2012)
Dihydroxyacid dehydratase (DHAD) is a key enzyme in the branched-chain amino acid biosynthetic pathway that exists in a variety of organisms, including fungi, plants and bacteria, but not humans. In this study we identified four putative DHAD genes f
Externí odkaz:
https://doaj.org/article/b03d888d70464448829ee7c9e6ac5f7e
Autor:
Timo Heikkila, Edward Wheatley, Diane Crighton, Ewald Schroder, Alexandra Boakes, Sarah J Kaye, Mokdad Mezna, Leon Pang, Mathew Rushbrooke, Andrew Turnbull, Michael F Olson
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24825 (2011)
MRCKα and MRCKβ (myotonic dystrophy kinase-related Cdc42-binding kinases) belong to a subfamily of Rho GTPase activated serine/threonine kinases within the AGC-family that regulate the actomyosin cytoskeleton. Reflecting their roles in myosin light
Externí odkaz:
https://doaj.org/article/2cc27aa9fe3442bd86351f46f0227c37
Publikováno v:
Journal of the American Veterinary Medical Association. 256:1225-1228
Autor:
Michael Bromley, Tiago Domingues Zucchi, Jaqueline Price, Sarah J. Kaye, Gethin Allen, Geoffrey Turner, David Keszenman-Pereyra, Jason David Oliver, Mike Birch
Publikováno v:
Fungal Genetics and Biology. 48:456-464
The mitochondrial phosphopantetheinyl transferase gene pptB of the opportunistic pathogen Aspergillus fumigatus has been identified and characterised. Unlike pptA, which is required for lysine biosynthesis, secondary metabolism, and iron assimilation
Autor:
Sarah J. Kaye, Katharine S. Dobb, John Leslie Thain, Lubomira Stateva, Jason David Oliver, Mike Birch, Nicola Beckmann
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143770 (2015)
PLoS ONE
PLoS ONE
Antifungal drugs acting via new mechanisms of action are urgently needed to combat the increasing numbers of severe fungal infections caused by pathogens such as Candida albicans. The phosphopantetheinyl transferase of Aspergillus fumigatus, encoded
Autor:
Mathew Rushbrooke, Ewald Schroder, Edward R. Wheatley, Sarah J. Kaye, Diane Crighton, Michael F. Olson, Mokdad Mezna, Timo Heikkila, Alexandra Boakes, Leon Pang, Andrew P. Turnbull
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24825 (2011)
PLoS ONE
PLoS ONE
MRCK alpha and MRCK beta (myotonic dystrophy kinase-related Cdc42-binding kinases) belong to a subfamily of Rho GTPase activated serine/threonine kinases within the AGC-family that regulate the actomyosin cytoskeleton. Reflecting their roles in myosi
Autor:
Sarah J. Kaye
Publikováno v:
American Journal of Dance Therapy. 23:120-122
Autor:
Victor M. Goldberg, Tetsuya Jinno, Edward M. Greenfield, Ashraf A. Ragab, Matthew C. Stewart, Sarah J. Kaye, Yanming Bi, Scott G. Kaar, John R. Carter, B. Alper Kilic
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 19(2)
Aseptic loosening is the most common cause of orthopaedic implant failure. This process is thought to be due to osteolysis induced by implant-derived wear particles. Teitelbaum and colleagues have recently developed a promising murine calvarial model
Autor:
Sarah J Kaye, Michael S. Harbuz, Allison J Fulford, Freddy M De Bree, David S. Jessop, Glenn N. Major, Toni L. Coventry
Publikováno v:
Journal of neuroimmunology. 106(1-2)
Endomorphin (EM)-1 and EM-2 are opioid tetrapeptides, reported within the central nervous system, which have very high specificity and affinity for the mu-opioid receptor. We have used newly developed and well-characterised radioimmunoassays (RIAs) i