Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sarah J Byrnes"'
Autor:
Janna Jamal Eddine, Thomas A Angelovich, Jingling Zhou, Sarah J Byrnes, Carolin Tumpach, Nadia Saraya, Emily Chalmers, Rory A Shepherd, Abigail Tan, Stephanie Marinis, Paul R Gorry, Jacob D Estes, Bruce J Brew, Sharon R Lewin, Sushama Telwatte, Michael Roche, Melissa J Churchill
Publikováno v:
PLoS Pathogens, Vol 20, Iss 8, p e1012446 (2024)
HIV persistence in the brain is a barrier to cure, and potentially contributes to HIV-associated neurocognitive disorders. Whether HIV transcription persists in the brain despite viral suppression with antiretroviral therapy (ART) and is subject to t
Externí odkaz:
https://doaj.org/article/a288983a01634826840f2cf6e23b2dd3
Autor:
Sarah J Byrnes, Kathleen Busman-Sahay, Thomas A Angelovich, Skyler Younger, Sol Taylor-Brill, Michael Nekorchuk, Stephen Bondoc, Rachel Dannay, Margaret Terry, Catherine R Cochrane, Trisha A Jenkins, Michael Roche, Claire Deleage, Steven E Bosinger, Mirko Paiardini, Bruce J Brew, Jacob D Estes, Melissa J Churchill
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011290 (2023)
HIV-associated neurocognitive disorders (HAND) affect ~40% of virally suppressed people with HIV (PWH), however, the precise viral dependent and independent changes to the brain are unclear. Here we characterized the CNS reservoir and immune environm
Externí odkaz:
https://doaj.org/article/a8b2d780e7df44039d495cd700b5e282
Autor:
Sarah J. Byrnes, Thomas A. Angelovich, Kathleen Busman-Sahay, Catherine R. Cochrane, Michael Roche, Jacob D. Estes, Melissa J. Churchill
Publikováno v:
Viruses, Vol 14, Iss 9, p 1997 (2022)
Human Immunodeficiency virus (HIV)-associated neurocognitive disorders are a major burden for people living with HIV whose viremia is stably suppressed with antiretroviral therapy. The pathogenesis of disease is likely multifaceted, with contribution
Externí odkaz:
https://doaj.org/article/7ed0552c021a4568aac3c9f296d8bbf9
Autor:
Catherine R. Cochrane, Thomas A. Angelovich, Sarah J. Byrnes, Emily Waring, Aleks C. Guanizo, Gemma S. Trollope, Jingling Zhou, Judith Vue, Lachlan Senior, Emma Wanicek, Janna Jamal Eddine, Matthew J. Gartner, Trisha A. Jenkins, Paul R. Gorry, Bruce J. Brew, Sharon R. Lewin, Jacob D. Estes, Michael Roche, Melissa J. Churchill
Publikováno v:
Annals of neurology. 92(4)
Human immunodeficiency virus (HIV) persistence in blood and tissue reservoirs, including the brain, is a major barrier to HIV cure and possible cause of comorbid disease. However, the size and replication competent nature of the central nervous syste