Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sarah J Blackwood"'
Autor:
Sarah J. Blackwood, Oscar Horwath, Marcus Moberg, Marjan Pontén, William Apró, Maria M. Ekblom, Filip J. Larsen, Abram Katz
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 324:E390-E401
Whether lipid-mediated insulin resistance occurs as a result of an increased or decreased capacity of skeletal muscle to oxidize lipids has been debated. We show that a 3-day fast results in increases in circulating lipids and insulin resistance in s
Autor:
Mikael Flockhart, Dominik Tischer, Lina C. Nilsson, Sarah J. Blackwood, Björn Ekblom, Abram Katz, William Apró, Filip J. Larsen
Publikováno v:
Acta Physiologica.
Autor:
Sarah J Blackwood, Oscar Horwath, Marcus Moberg, Marjan Pontén, William Apró, Maria M Ekblom, Filip J Larsen, Abram Katz
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:e2729-e2737
Context Muscle fiber composition is associated with peripheral insulin action. Objective We investigated whether extreme differences in muscle fiber composition are associated with alterations in peripheral insulin action and secretion in young, heal
Autor:
Fabian Nordström, Rasmus Liegnell, William Apró, Sarah J. Blackwood, Abram Katz, Marcus Moberg
Publikováno v:
American journal of physiology. Cell physiology.
Gi-coupled protein receptor 81 (GPR81) was first identified in adipocytes as a receptor for l-lactate, which upon binding inhibits cyclicAMP (cAMP)-protein kinase (PKA)-cAMP-response element binding (CREB) signaling. Moreover, incubation of myotubes
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 320:E691-E701
Phosphorylase is one of the most carefully studied proteins in history, but knowledge of its regulation during intense muscle contraction is incomplete. Tyrosine nitration of purified preparations of skeletal muscle phosphorylase results in inactivat
Autor:
Sarah J Blackwood, Brad A. Sutherland, David W. Howells, Ciaran J Ramsay, Michelle A. Keske, Dino Premilovac
Publikováno v:
J Cereb Blood Flow Metab
Direct and real-time assessment of cerebral hemodynamics is key to improving our understanding of cerebral blood flow regulation in health and disease states such as stroke. While a number of sophisticated imaging platforms enable assessment of cereb
Autor:
Abram Katz, Sarah J. Blackwood
Publikováno v:
Pflugers Archiv
Fight or flight is a biologic phenomenon that involves activation of β-adrenoceptors in skeletal muscle. However, how force generation is enhanced through adrenergic activation in different muscle types is not fully understood. We studied the effect
Publikováno v:
Journal of Applied Physiology. 126:1103-1109
The effects of temperature elevation after intense repeated contractions on glycogen and energy metabolism as well as contractile function of isolated mouse soleus muscle (slow twitch, oxidative) were investigated. Muscles were stimulated electricall
Autor:
Stephen M. Richards, Sarah J Blackwood, Ryan D. Russell, Donghua Hu, Michelle A. Keske, Aascha A Brown, Renee M. Dwyer, Dino Premilovac, Stephen Rattigan
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 44:143-149
Skeletal muscle is an important site for insulin to regulate blood glucose levels. It is estimated that skeletal muscle is responsible for ~80% of insulin-mediated glucose disposal in the post-prandial period. The classical action of insulin to incre
Publikováno v:
American journal of physiology. Cell physiology. 315(5)
The effects of heating on glycogen synthesis (incorporation of [14C]glucose into glycogen) and accumulation after intense repeated contractions were investigated. Isolated mouse extensor digitorum longus muscle (type II) was stimulated electrically t