Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sarah J, Boffey"'
Autor:
Janet A. Jackson, Simon T. Barry, Sandra R. Brave, Sharon Barnett, Graham Richmond, Lee Cooper, Neil H. James, Neil R. Smith, Jane Kendrew, Stephen R. Wedge, Paula J. Valentine, Taylor Sian Tomiko, Michael D. Walker, Sarah J. Boffey, Sarah Beck, Laurent Francois Andre Hennequin, Lyndsey L. Kilburn, Rosemary Chester, Peter F. Wadsworth, Alison L. Bigley, Juliane M. Jürgensmeier, Donald J. Ogilvie, Jon Curwen, Michael Dukes
Publikováno v:
Cancer research. 65(10)
Inhibition of vascular endothelial growth factor-A (VEGF) signaling is a promising therapeutic approach that aims to stabilize the progression of solid malignancies by abrogating tumor-induced angiogenesis. This may be accomplished by inhibiting the
Autor:
Stephen R, Wedge, Donald J, Ogilvie, Michael, Dukes, Jane, Kendrew, Rosemary, Chester, Janet A, Jackson, Sarah J, Boffey, Paula J, Valentine, Jon O, Curwen, Helen L, Musgrove, George A, Graham, Gareth D, Hughes, Andrew P, Thomas, Elaine S E, Stokes, Brenda, Curry, Graham H P, Richmond, Peter F, Wadsworth, Alison L, Bigley, Laurent F, Hennequin
Publikováno v:
Cancer research. 62(16)
ZD6474 [N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine]is a potent, p.o. active, low molecular weight inhibitor of kinase insert domain-containing receptor [KDR/vascular endothelial growth factor receptor (