Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sarah Hulin-Curtis"'
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 191-199 (2017)
Approximately 50% of coronary artery bypass grafts using the autologous saphenous vein fail within 10 years due to intimal thickening. This study examined whether a gene therapy approach that selectively kills Wnt/β-catenin/T cell factor (TCF) activ
Externí odkaz:
https://doaj.org/article/c09c64849b9a48fcb6b9185d344effb9
Publikováno v:
Viruses, Vol 7, Iss 11, Pp 6009-6042 (2015)
Adenoviruses (Ad) are commonly used both experimentally and clinically, including oncolytic virotherapy applications. In the clinical area, efficacy is frequently hampered by the high rates of neutralizing immunity, estimated as high as 90% in some p
Externí odkaz:
https://doaj.org/article/d7cc706d6e144c2e91f47c11f68360b8
Publikováno v:
Oxford Open Immunology
The role of obesity in the pathophysiology of respiratory virus infections has become particularly apparent during the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, where obese patients are twice as likely to suffer f
Autor:
Tehmina Bharuchq, Bruce MacLachlan, Ceri Fielding, Adrian L Smith, Fadi Issa, Emily Thornton, Raphael Sanches Peres, Calliope A Dendrou, Dorothée L Berthold, Liliana Cifuentes, Alicia Teijeira Crespo, Elizabeth H Mann, Arvind Sami, Anne Chauveau, Dominic S Alonzi, Anís Gammage, Fabian Fischer, Valentina M T Bart, Fangfang Lu, Miriam O'Hanlon, Lynn B Dustin, Pragati Sabberwal, Ewoud B. Compeer, Mariana Borsa, Rowie Borst, Hannah Almuttaqi, David J Ahern, Eleanor J Pring, Emma Jones, Ester Gea-Mallorquí, Kate Liddiard, Dingxi Zhou, Amy Cross, Sara Danielli, Max Quastel, Shayda Maleki-Toyserkani, Owen R Moon, Ruban Rex Peter Durairaj, Vicky Batchelor, Barbora Schonfeldova, Angus K T Wann, Lorenzo Capitani, Petros Ligoxygakis, Sandra Dimonte, Clara Eléonore Pavillet, Lion F K Uhl, Luke C Davies, Kristin Ladell, Stephanie Jean Hanna, Felix Richter, Freya R Shepherd, Sarah Hulin-Curtis, Stephanie Burnell, Amy Susan Codd, Anita Milicic, Quentin Sattentau, Juliane Brun, David Oliver Scourfield, Sophie Reed, Jan Rehwinkel, Ghada Alsaleh, D Oliver Scourfield, Michael Tellier, Reginald James Matthews, Eleanor Pring, Emma Mitchell, Anna Katharina Simon, Joseph D Wilson, Niamh Richmond, Van Dien Nguyen, Sarah N Lauder, Zihan Zhu, Tharini A Selvakumar, Ana Pires, Cariad Shorten, Richard Williams, Erinke van Grinsven, Sarah Galloway, Aljawharah Alrubayyi, Stephanie J. Hanna, Felix Clemens Richter, Julie M Mazet, Dimitra Peppa, Clarissa Coveney, Awen Gallimore, Cornelia Heuberger, Owen Moon, Ruth Jones, Helene Borrmann, Arthur Dyer, Lucy Chapman, Jelena S Bezbradica, Andrew Godkin, Rebecca Bayliss, Amy S. Codd, Anna M Marzeda, Athena Cavounidis, Patrícia R S Rodrigues, Alice J B Robinson, Ewoud Bernardus Compeer
Publikováno v:
Oxford Open Immunology
Destabilization of balanced immune cell numbers and frequencies is a common feature of viral infections. This occurs due to, and further enhances, viral immune evasion and survival. Since the discovery of the Severe Acute Respiratory Syndrome coronav
Autor:
Robert Andrews, Sarah Nicol Lauder, Aaron Wall, Kathryn Smart, Bruce J. MacLachlan, Meriem Attaf, Pierre J. Rizkallah, Dhanasekaran Vijaykrishna, Yuan Chen, Georgina H. Mason, Andrew James Godkin, Garry Dolton, Mikhail Shugay, David K. Cole, Angharad Lloyd, Cristina Rius, Andrew K. Sewell, Miguel L. Grau, Andrea J. A. Schauenburg, Alexander Greenshields-Watson, Hywel Hughes, Kathryn E. Strange, Awen Gallimore, James Geary, Sarah Hulin-Curtis, Thomas Whalley
Publikováno v:
Cell Reports, Vol 32, Iss 2, Pp 107885-(2020)
Summary: T cell recognition of peptides presented by human leukocyte antigens (HLAs) is mediated by the highly variable T cell receptor (TCR). Despite this built-in TCR variability, individuals can mount immune responses against viral epitopes by usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75db8e6035331d3fe6e4c0c6bffbf5e9
Autor:
Emily A. Bates, Alan L. Parker, Alexander T. Baker, James A. Davies, Davor Nestić, Tabitha G Cunliffe, Dragomira Majhen, Sarah Hulin-Curtis, John D. Chester
Publikováno v:
Cancer Gene Therapy
Oncolytic virotherapies (OV) based on human adenoviral (HAdV) vectors hold significant promise for the treatment of advanced ovarian cancers where local, intraperitoneal delivery to tumour metastases is feasible, bypassing many complexities associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7544aa2009f4bb73a93cd88f020bbe
https://www.bib.irb.hr/1071192
https://www.bib.irb.hr/1071192
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 5, Iss C, Pp 191-199 (2017)
Curtis, S, Williams, H, Wadey, K, Sala-Newby, G & George, S 2017, ' Targeting Wnt/β-Catenin Activated Cells with Dominant-Negative N-cadherin to Reduce Neointima Formation ', Molecular Therapy-Methods and Clinical Development, vol. 5, pp. 191-199 . https://doi.org/10.1016/j.omtm.2017.04.009
Molecular Therapy. Methods & Clinical Development
Curtis, S, Williams, H, Wadey, K, Sala-Newby, G & George, S 2017, ' Targeting Wnt/β-Catenin Activated Cells with Dominant-Negative N-cadherin to Reduce Neointima Formation ', Molecular Therapy-Methods and Clinical Development, vol. 5, pp. 191-199 . https://doi.org/10.1016/j.omtm.2017.04.009
Molecular Therapy. Methods & Clinical Development
Approximately 50% of coronary artery bypass grafts using the autologous saphenous vein fail within 10 years due to intimal thickening. This study examined whether a gene therapy approach that selectively kills Wnt/β-catenin/T cell factor (TCF) activ
Autor:
Yuan Chen, Stephanie E A Burnell, Michael M. Davies, Rachel Hargest, Adam Christian, Andrew James Godkin, Emma Campbell, Robert Andrews, Simon Phillips, Awen Gallimore, Sarah Hulin-Curtis, Alan L. Parker, Michelle Somerville, Alexander Greenshields-Watson, James A. Davies, Martin J. Scurr, Kevin E. Ashelford, Richard J. Stanton
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 26(13)
Purpose: Broadly expressed, highly differentiated tumor-associated antigens (TAA) can elicit antitumor immunity. However, vaccines targeting TAAs have demonstrated disappointing clinical results, reflecting poor antigen selection and/or immunosuppres
Publikováno v:
Viruses, Vol 7, Iss 11, Pp 6009-6042 (2015)
Viruses
Viruses
Adenoviruses (Ad) are commonly used both experimentally and clinically, including oncolytic virotherapy applications. In the clinical area, efficacy is frequently hampered by the high rates of neutralizing immunity, estimated as high as 90% in some p
Autor:
Roger Smith, Kristien Verheyen, Sarah Hulin-Curtis, A. M. Murphy, Joanna S. Price, L. J. Tully
Publikováno v:
Equine Veterinary Journal. 46:289-293
Reasons for performing the study To explore whether genetic susceptibility is a potential risk factor for superficial digital flexor (SDF) tendinopathy in Thoroughbred (TB) racehorses. Objectives To identify informative single nucleotide polymorphism