Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sarah Hatef"'
Autor:
Roger Abounader, Lloyd S. Gray, Emanuel F. Petricoin, Stephen D. Turner, David Schiff, Eli E. Bar, Jeongwu Lee, Christopher Papanicolas, Sarah Hatef, Alexander F. Koeppel, Isela Gallagher, Julia Wulfkuhle, Mary Pahuski, Baomin Wang, Fang Yuan, Nichola Cruickshanks, Ying Zhang
Supplementary methods containing descriptions of PCR primer sequences, Reverse Phase Protein Arrays, RNA-seq, and Rescue Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b04dd685fe00c0cdfbe7215d5b464da
https://doi.org/10.1158/0008-5472.22413443.v1
https://doi.org/10.1158/0008-5472.22413443.v1
Autor:
Roger Abounader, Lloyd S. Gray, Emanuel F. Petricoin, Stephen D. Turner, David Schiff, Eli E. Bar, Jeongwu Lee, Christopher Papanicolas, Sarah Hatef, Alexander F. Koeppel, Isela Gallagher, Julia Wulfkuhle, Mary Pahuski, Baomin Wang, Fang Yuan, Nichola Cruickshanks, Ying Zhang
Supplementary figures: 1): molecular structure of mibefradil, 2) Mibefradil effects on HIFs, 3) effects of sh-RNA inhibition of Cav3.2 in GSCs, 4) Schematic summary of the findings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abf13a9118e0ab59d5144def36f51f2
https://doi.org/10.1158/0008-5472.22413440
https://doi.org/10.1158/0008-5472.22413440
Autor:
Roger Abounader, Lloyd S. Gray, Emanuel F. Petricoin, Stephen D. Turner, David Schiff, Eli E. Bar, Jeongwu Lee, Christopher Papanicolas, Sarah Hatef, Alexander F. Koeppel, Isela Gallagher, Julia Wulfkuhle, Mary Pahuski, Baomin Wang, Fang Yuan, Nichola Cruickshanks, Ying Zhang
Glioblastoma (GBM) stem-like cells (GSC) promote tumor initiation, progression, and therapeutic resistance. Here, we show how GSCs can be targeted by the FDA-approved drug mibefradil, which inhibits the T-type calcium channel Cav3.2. This calcium cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55cd1f54f8281700ec886b6615dbf2b4
https://doi.org/10.1158/0008-5472.c.6508712.v1
https://doi.org/10.1158/0008-5472.c.6508712.v1
Autor:
Jeffrey, Hatef, Sarah, Hatef, Joseph P, Drain, Joseph D, Tobias, David, Martin, Richard, Shell, Margaret, Chase, Allan, Beebe, Walter, Samora, Jan, Klamar
Publikováno v:
Spine Deformity. 10:689-696
To review the results of a postoperative respiratory pathway for patients with muscular dystrophy (MD) and spinal muscular atrophy (SMA) undergoing spinal surgery.With IRB approval, a retrospective review was done on all patients with SMA and MD unde
Autor:
Azeem Tariq Malik, Jesse H. Morris, Mathangi Sridharan, Andrew S. Neviaser, Julie Y. Bishop, Gregory L. Cvetanovich, Safdar N. Khan, Sarah Hatef
Publikováno v:
Seminars in Arthroplasty: JSES. 31:629-634
Introduction The U.S. News & World Report (USNWR) hospital rankings remain the most publicly referenced system for identifying top hospitals for each specialty. The current study aims to evaluate whether there are any differences in outcomes and cost
Publikováno v:
Current Orthopaedic Practice. 32:474-478
Publikováno v:
HAND. :155894472210756
Background: We sought to determine whether any relevant patient, fracture, surgical, or postoperative characteristics are associated with loss of reduction after plate fixation of isolated olecranon fractures in adults. Methods: Patients who underwen
Autor:
Julie Y. Bishop, Gregory L. Cvetanovich, Jesse H. Morris, Azeem Tariq Malik, Sarah Hatef, Andrew S. Neviaser
Publikováno v:
Arthroscopy : the journal of arthroscopicrelated surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 37(4)
To identify intraoperative drivers of cost associated with arthroscopic rotator cuff repairs (RCRs) through analysis of an institutional database.This was a single-institution retrospective review of arthroscopic RCRs performed at an ambulatory surgi
Autor:
Isela Gallagher, Julia Wulfkuhle, Christopher Papanicolas, Roger Abounader, David Schiff, Mary Pahuski, Fang Yuan, Ying Zhang, Jeongwu Lee, Baomin Wang, Eli E. Bar, Alexander F. Koeppel, Sarah Hatef, Stephen D. Turner, Emanuel F. Petricoin, Lloyd S. Gray, Nichola Cruickshanks
Glioblastoma (GBM) stem-like cells (GSC) promote tumor initiation, progression, and therapeutic resistance. Here, we show how GSCs can be targeted by the FDA-approved drug mibefradil, which inhibits the T-type calcium channel Cav3.2. This calcium cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283ace7523fb4db5247b72162683f36d
https://europepmc.org/articles/PMC5505315/
https://europepmc.org/articles/PMC5505315/
Autor:
Stephen D. Turner, Julia D. Wulfkuhle, David Schiff, Isela Gallagher, S. Phan, Sarah Hatef, Emanuel F. Petricoin, Ying Zhang, Nichola Cruickshanks, Roger Abounader, Alexander F. Koeppel
Publikováno v:
Cancer Research. 77:102-102
Glioblastoma (GBM) is the most common and most lethal primary malignant brain tumor. The receptor tyrosine kinase MET is frequently upregulated or over activated in GBM. Clinically applicable MET inhibitors have been developed and tested in the lab a