Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sarah Hafith"'
Autor:
Maarten L. J. Doornbos, Annelien J.M. Zweemer, Dean Stamos, Hilde Vrieling, Jeffrey Abt, John Saunders, Indira Nederpelt, Sarah Hafith, Henk de Vries, Laura H. Heitman, Martine J. Smit, Raymond S. Gross, Adriaan P. IJzerman
Publikováno v:
Molecular Pharmacology, 2013(84), 551-561. American Society for Pharmacology and Experimental Therapeutics
Zweemer, A J, Nederpelt, I, Vrieling, H, Hafith, S, Doornbos, M L, de Vries, H, Abt, J, Gross, R, Stamos, D, Saunders, J, Smit, M J, IJzerman, A P & Heitman, L H 2013, ' Multiple Binding Sites for Small Molecule Antagonists at the Chemokine Receptor CCR2 ', Molecular Pharmacology, vol. 2013, no. 84, pp. 551-561 . https://doi.org/10.1124/mol.113.086850
Zweemer, A J, Nederpelt, I, Vrieling, H, Hafith, S, Doornbos, M L, de Vries, H, Abt, J, Gross, R, Stamos, D, Saunders, J, Smit, M J, IJzerman, A P & Heitman, L H 2013, ' Multiple Binding Sites for Small Molecule Antagonists at the Chemokine Receptor CCR2 ', Molecular Pharmacology, vol. 2013, no. 84, pp. 551-561 . https://doi.org/10.1124/mol.113.086850
The chemokine receptor CCR2 is a G protein-coupled receptor that is activated primarily by the endogenous CC chemokine ligand 2 (CCL2). Many different small-molecule antagonists have been developed to inhibit this receptor, as it is involved in a var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876056dc6ab3615ab4c65f282a968413
https://doi.org/10.1124/mol.113.086850
https://doi.org/10.1124/mol.113.086850
Autor:
Louise van der Weerd, Albert D. Windhorst, Athanasios Metaxas, Mark Overhand, Mick M. Welling, Sarah Hafith, Wim Jiskoot, Rob J.A. Nabuurs, Adrianus M. C. H. van den Nieuwendijk, Maaike E. de Backer, Varsha V. Kapoerchan, Herman S. Overkleeft, Mark A. van Buchem
Publikováno v:
Bioorganic and Medicinal Chemistry, 24(23), 6139-6148
Bioorganic and Medicinal Chemistry, 24(23), 6139-6148. Elsevier Limited
Nabuurs, R J A, Kapoerchan, V V, Metaxas, A, Hafith, S, de Backer, M, Welling, M M, Jiskoot, W, van den Nieuwendijk, A M C H, Windhorst, A D, Overkleeft, H S, van Buchem, M A, Overhand, M & van der Weerd, L 2016, ' Bis-pyridylethenyl benzene as novel backbone for amyloid-β binding compounds ', Bioorganic and Medicinal Chemistry, vol. 24, no. 23, pp. 6139-6148 . https://doi.org/10.1016/j.bmc.2016.05.022
Bioorganic and Medicinal Chemistry, 24(23), 6139-6148. Elsevier Limited
Nabuurs, R J A, Kapoerchan, V V, Metaxas, A, Hafith, S, de Backer, M, Welling, M M, Jiskoot, W, van den Nieuwendijk, A M C H, Windhorst, A D, Overkleeft, H S, van Buchem, M A, Overhand, M & van der Weerd, L 2016, ' Bis-pyridylethenyl benzene as novel backbone for amyloid-β binding compounds ', Bioorganic and Medicinal Chemistry, vol. 24, no. 23, pp. 6139-6148 . https://doi.org/10.1016/j.bmc.2016.05.022
Detection of cerebral β-amyloid (Aβ) by targeted contrast agents is of great interest for in vivo diagnosis of Alzheimer's disease (AD). Partly because of their planar structure several bis-styrylbenzenes have been previously reported as potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365063b4bf0a0ae018a5ea2bd3be16bd
http://hdl.handle.net/1887/112175
http://hdl.handle.net/1887/112175
