Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sarah Haebe"'
Autor:
Deepak Bararia, Johannes A. Hildebrand, Sebastian Stolz, Sarah Haebe, Stefan Alig, Christopher P. Trevisani, Francisco Osorio-Barrios, Michael D. Bartoschek, Michael Mentz, Alessandro Pastore, Erik Gaitzsch, Michael Heide, Vindi Jurinovic, Katharina Rautter, Jay Gunawardana, Muhammed B. Sabdia, Monika Szczepanowski, Julia Richter, Wolfram Klapper, Abner Louissaint, Jr., Christina Ludwig, Sebastian Bultmann, Heinrich Leonhardt, Sebastian Eustermann, Karl-Peter Hopfner, Wolfgang Hiddemann, Michael von Bergwelt-Baildon, Christian Steidl, Robert Kridel, Joshua W.D. Tobin, Maher K. Gandhi, David M. Weinstock, Marc Schmidt-Supprian, Menyhárt B. Sárosi, Martina Rudelius, Verena Passerini, Josef Mautner, Oliver Weigert
Publikováno v:
Cell Reports, Vol 31, Iss 5, Pp - (2020)
Summary: Tumor cells orchestrate their microenvironment. Here, we provide biochemical, structural, functional, and clinical evidence that Cathepsin S (CTSS) alterations induce a tumor-promoting immune microenvironment in follicular lymphoma (FL). We
Externí odkaz:
https://doaj.org/article/0a5e722ca6e94029b574353537c7475f
Autor:
Angela Garding, Nupur Bhattacharya, Sarah Haebe, Frederike Müller, Dieter Weichenhan, Irina Idler, Katja Ickstadt, Stephan Stilgenbauer, Daniel Mertens
Publikováno v:
Haematologica, Vol 98, Iss 2 (2013)
Chronic lymphocytic leukemia is characterized by the accumulation of B cells that are resistant to apoptosis. This resistance is induced by pro-survival stimuli from the microenvironment. TCL1 and ATM are central to the pathogenesis of the disease an
Externí odkaz:
https://doaj.org/article/80d888482661497582b471507377c554
Autor:
Michael Mentz, William Keay, Carolin Dorothea Strobl, Martina Antoniolli, Louisa Adolph, Michael Heide, Axel Lechner, Sarah Haebe, Elisa Osterode, Robert Kridel, Christoph Ziegenhain, Lucas Esteban Wange, Johannes Adrian Hildebrand, Tanaya Shree, Elisabeth Silkenstedt, Annette M. Staiger, German Ott, Heike Horn, Monika Szczepanowski, Julia Richter, Ronald Levy, Andreas Rosenwald, Wolfgang Enard, Ursula Zimber-Strobl, Michael von Bergwelt-Baildon, Wolfgang Hiddemann, Wolfram Klapper, Marc Schmidt-Supprian, Martina Rudelius, Deepak Bararia, Verena Passerini, Oliver Weigert
Publikováno v:
Leukemia 36, 2281–2292 (2022)
The variable clinical course of follicular lymphoma (FL) is determined by the molecular heterogeneity of tumor cells and complex interactions within the tumor microenvironment (TME). IL-4 producing follicular helper T cells (TFH) are critical compone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52b2cd1ee1154f74b7bbd0cba9836e2
https://doi.org/10.1038/s41375-022-01641-x
https://doi.org/10.1038/s41375-022-01641-x
Autor:
Tanaya Shree, Kelly L. Mooney, Stefano Testa, Brock A. Martin, Steven R. Long, Ronald Levy, Matthew J. Frank, Debra K. Czerwinski, Sarah Haebe
Publikováno v:
Cancer Cytopathology. 130:231-237
Background Fine-needle aspiration (FNA) is used to diagnose malignancies, recurrences, and metastases. The procedure is quick and well tolerated and can be facilitated by ultrasound guidance. Methods This article describes the authors' experience in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06eb5193de4d6734faa8d53d58eacf7a
https://doi.org/10.1002/cncy.22531
https://doi.org/10.1002/cncy.22531
Autor:
Susan M. Grimes, Heon Seok Kim, Sharmili Roy, Anuja Sathe, Carlos I. Ayala, Alison F. Almeda-Notestine, Sarah Haebe, Tanaya Shree, Ronald Levy, Billy T. Lau, Hanlee P. Ji
In this proof-of-concept study, we developed a single cell method that identifies somatic alterations found in coding regions of mRNAs and integrates these mutation genotypes with their matching cell transcriptomes. We used nanopore adaptive sampling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8df5a8376e4c8a444fc7f04f4a9b71a
https://doi.org/10.1101/2022.11.22.517284
https://doi.org/10.1101/2022.11.22.517284
Autor:
Sarah Haebe, Tanaya Shree, Grady Day, Debra K. Czerwinski, Anuja Sathe, Susan M. Grimes, Steven R. Long, Brock Martin, Michael G. Ozawa, Hanlee P. Ji, Ronald Levy
Publikováno v:
Blood. 140:9211-9212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fc0c3e1885c4272a20363fbea163a70
https://doi.org/10.1182/blood-2022-164763
https://doi.org/10.1182/blood-2022-164763
Autor:
Alfred C. Feller, Harald Stein, Wolfram Klapper, Andreas Rosenwald, Vindi Jurinovic, Michael Unterhalt, Verena Passerini, William David Keay, Christiane Pott, Annette M. Staiger, Stefan Alig, German Ott, Heike Horn, Sarah Haebe, Erik Gaitzsch, Mohammad Shahrokh Esfahani, Ash A. Alizadeh, Natyra Tahiri, Martin Dreyling, Johannes C. Hellmuth, Christian Schmidt, Eva Hoster, Martin-Leo Hansmann, Oliver Weigert, Wolfgang Hiddemann, Anna-Katharina Zoellner
Publikováno v:
Blood Adv
High-dose therapy and autologous stem cell transplantation (HDT/ASCT) is an effective salvage treatment for eligible patients with follicular lymphoma (FL) and early progression of disease (POD). Since the introduction of rituximab, HDT/ASCT is no lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3143b3993776c71324f3558a99a9033c
https://doi.org/10.1182/bloodadvances.2020002546
https://doi.org/10.1182/bloodadvances.2020002546
Autor:
Jeffrey A. Norton, Andrew S. Lee, Benedikt Westphalen, Sarah Haebe, Wen Jiang, Wan Xing Hong, Ronald Levy
Publikováno v:
Clin Cancer Res
The unprecedented benefits of immunotherapy in advanced malignancies have resulted in increased interests in exploiting immune stimulatory agents in earlier-stage solid tumors in the neoadjuvant setting. However, systemic delivery of immunotherapies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5efb10bee828a3d46f0850b81b3921
https://doi.org/10.1158/1078-0432.ccr-19-3642
https://doi.org/10.1158/1078-0432.ccr-19-3642
Autor:
Valentine Murigneux, J. Lynn Fink, Colm Keane, Oliver Weigert, Santiyagu M. Savarimuthu Francis, Frank Vari, Simone Birch, Maher K. Gandhi, Christian Steidl, Robert Kridel, Thanh Hoang, Wolfram Klapper, Li Huang, Nicholas Matigian, Li Li, Michelle N. Wykes, Laurie H. Sehn, Peter Mollee, Joshua W.D. Tobin, Sarah Haebe, Soi Cheng Law, Jay Gunawardana, Justina Lee, Vindi Jurinovic
Publikováno v:
Journal of Clinical Oncology
PURPOSE Understanding the immunobiology of the 15% to 30% of patients with follicular lymphoma (FL) who experience progression of disease within 24 months (POD24) remains a priority. Solid tumors with low levels of intratumoral immune infiltration ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9050ac90c771dd0d74aa693b2b9263db
http://europepmc.org/articles/PMC6881104
http://europepmc.org/articles/PMC6881104
Autor:
Sarah Haebe, William Keay, Stefan Alig, Anne‐Wiebe Mohr, Larissa K. Martin, Michael Heide, Ramona Secci, Stefan Krebs, Helmut Blum, Andreas Moosmann, Abner Louissaint, David M. Weinstock, Silvia Thoene, Michael Bergwelt‐Baildon, Jürgen Ruland, Deepak Bararia, Oliver Weigert
Publikováno v:
Br. J. Haematol., DOI: 10.1111/bjh.17990 (2021)
Relapsed follicular lymphoma (FL) can arise from common progenitor cells (CPCs). Conceptually, CPC-defining mutations are somatic alterations shared by the initial and relapsed tumours, mostly B-cell leukaemia/lymphoma 2 (BCL2)/immunoglobulin heavy l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ef3be7bb1f38ad9f5a64d20620c7a3
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63936
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63936