Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sarah Höfs"'
Autor:
Selene Mogavero, Sarah Höfs, Alexa N. Lauer, Rita Müller, Sascha Brunke, Stefanie Allert, Franziska Gerwien, Sabrina Groth, Edward Dolk, Duncan Wilson, Thomas Gutsmann, Bernhard Hube
Publikováno v:
Toxins, Vol 14, Iss 12, p 874 (2022)
Candida albicans produces an important virulence factor, the hypha-associated Ece1-derived secreted peptide toxin candidalysin, which is crucial for the establishment of mucosal and systemic infections. C. albicans has also long been known to be hemo
Externí odkaz:
https://doaj.org/article/fe0ef4d748e54acaa7575ef1142cb32f
Autor:
Simona Ioana Iancu, Shirley X. Tang, Manohursingh Runglall, Antje Häder, Julian R. Naglik, Betty Hebecker, Toni M. Förster, Duncan Wilson, Robert T. Wheeler, Remi L. Gratacap, Jon Robbins, Oliver Bader, Sarah Höfs, Ernesto Cota, Gema Vizcay, Jonathan P. Richardson, Nessim Kichik, Mariana Blagojevic, Ting Luo, Olaf Kniemeyer, Julia Wernecke, Bernhard Hube, Thomas Krüger, David L. Moyes, Selene Mogavero, Celia Murciano, Lydia Kasper, Oliver Kurzai, Thomas Gutsmann, Selvam Thavaraj
Publikováno v:
Nature 532(7597), 64-68 (2016). doi:10.1038/nature17625
Nature
Moyes, D L, Wilson, D, Richardson, J P, Mogavero, S, Tang, S X, Wernecke, J, Hofs, S, Gratacap, R L, Robbins, J, Runglall, M, Murciano, C, Blagojevic, M, Thavaraj, S, Forster, T M, Hebecker, B, Kasper, L, Vizcay-Barrena, G, Iancu, S I, Kichik, N, Hader, A, Kurzai, O, Luo, T, Kruger, T, Kniemeyer, O, Cota, E, Bader, O, Bader, O, Wheeler, R T, Gutsmann, T, Hube, B & Naglik, J R 2016, ' Candidalysin is a fungal peptide toxin critical for mucosal infection ', NATURE, vol. 532, no. 7597, pp. 64-68 . https://doi.org/10.1038/nature17625
Nature
Moyes, D L, Wilson, D, Richardson, J P, Mogavero, S, Tang, S X, Wernecke, J, Hofs, S, Gratacap, R L, Robbins, J, Runglall, M, Murciano, C, Blagojevic, M, Thavaraj, S, Forster, T M, Hebecker, B, Kasper, L, Vizcay-Barrena, G, Iancu, S I, Kichik, N, Hader, A, Kurzai, O, Luo, T, Kruger, T, Kniemeyer, O, Cota, E, Bader, O, Bader, O, Wheeler, R T, Gutsmann, T, Hube, B & Naglik, J R 2016, ' Candidalysin is a fungal peptide toxin critical for mucosal infection ', NATURE, vol. 532, no. 7597, pp. 64-68 . https://doi.org/10.1038/nature17625
Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial pathogens which disrupt epithelial barrier function, damage cells and activate or modulate host immune responses. Such toxins have not been identified previous
Publikováno v:
Journal of Microbiology. 54:149-169
The interaction between Candida albicans and its host cells is characterized by a complex interplay between the expression of fungal virulence factors, which results in adherence, invasion and cell damage, and the host immune system, which responds b