Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Sarah Gwynne"'
Autor:
Somnath Mukherjee, Christopher N. Hurt, Richard Adams, Andrew Bateman, Kevin M. Bradley, Sarah Bridges, Stephen Falk, Gareth Griffiths, Sarah Gwynne, Christopher M. Jones, Philip J. Markham, Tim Maughan, Lisette S. Nixon, Ganesh Radhakrishna, Rajarshi Roy, Simon Schoenbuchner, Hamid Sheikh, Emiliano Spezi, Maria Hawkins, Thomas D.L. Crosby
Publikováno v:
EClinicalMedicine, Vol 61, Iss , Pp 102059- (2023)
Summary: Background: The utility of early metabolic response assessment to guide selection of the systemic component of definitive chemoradiotherapy (dCRT) for oesophageal cancer is uncertain. Methods: In this multi-centre, randomised, open-label, ph
Externí odkaz:
https://doaj.org/article/138ca15545ee408b9e0a95d7b868e614
Publikováno v:
Oncology Reviews, Vol 2, Iss 1, Pp 53-60 (2011)
The survival rate for stage 3 and 4 melanoma is very poor. In the absence of effective treatments for metastatic disease focus has shifted to the adjuvant setting. While we are now able to identify those who are at high risk of recurrence the role of
Externí odkaz:
https://doaj.org/article/c8220817b5ee4a7f8b8f7d5c35387e67
Autor:
Andrew Godkin, Awen Gallimore, Robert Hills, Richard Harrop, Daniel Blount, Sarah Gwynne, Robert Jones, Alison Brewster, Richard Adams, Hayley Bridgeman, Kathryn Smart, Amanda Thomson, David Roberts, Anja Bloom, Tom Pembroke, Martin Scurr
Purpose: Anticancer T-cell responses can control tumors, but immunosuppressive mechanisms in vivo prevent their function. The role of regulatory T cells (Tregs) in metastatic colorectal cancer is unclear. We have previously shown depletion of Tregs e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1f48485911346057d5a28de4595efc
https://doi.org/10.1158/1078-0432.c.6525245
https://doi.org/10.1158/1078-0432.c.6525245
Autor:
Andrew Godkin, Awen Gallimore, Robert Hills, Richard Harrop, Daniel Blount, Sarah Gwynne, Robert Jones, Alison Brewster, Richard Adams, Hayley Bridgeman, Kathryn Smart, Amanda Thomson, David Roberts, Anja Bloom, Tom Pembroke, Martin Scurr
Supplementary Figure 1. CONSORT diagram. Supplementary Figure 2. 5T4 peptide pools and matrix system. Supplementary Figure 3. B-cell number in response to cyclophosphamide. Supplementary Figure 4. Expression of activation markers in T-cell subsets du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccf646f32661490d9797c502cb70e8a
https://doi.org/10.1158/1078-0432.22462886.v1
https://doi.org/10.1158/1078-0432.22462886.v1
Autor:
Somnath Mukherjee, Christopher Nicholas Hurt, Richard A. Adams, Andrew Bateman, Kevin Bradley, Sarah Bridges, Stephen Falk, Gareth Griffiths, Sarah Gwynne, Christopher Jones, Philip Markham, Tim Maughan, Lisette Nixon, Ganesh Radhakrishna, Rajarshi Roy, Simon Schoenbuchner, Hamid Sheikh, Emiliano Spezi, Maria Hawkins, Tom Crosby
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ca8ed5984fa1dc6a837fdc8a8f3c067
https://doi.org/10.2139/ssrn.4380032
https://doi.org/10.2139/ssrn.4380032
Autor:
S. Prosser, Hanna Rahbek Mortensen, Sarah Gwynne, M. A Hawkins, Ganesh Radhakrishna, O. Nicholas
Publikováno v:
Nicholas, O, Prosser, S, Mortensen, H R, Radhakrishna, G, Hawkins, M A & Gwynne, S H 2021, ' The Promise of Proton Beam Therapy for Oesophageal Cancer : A Systematic Review of Dosimetric and Clinical Outcomes ', Clinical Oncology, vol. 33, no. 8, pp. e339-e358 . https://doi.org/10.1016/j.clon.2021.04.003
Aims Due to its physical advantages over photon radiotherapy, proton beam therapy (PBT) has the potential to improve outcomes from oesophageal cancer. However, for many tumour sites, high-quality evidence supporting PBT use is limited. We carried out
Autor:
Simon Gollins, Rajarshi Roy, Maria A. Hawkins, Gareth Griffiths, Tim Maughan, Lisette Sheena Nixon, Chris Nicholas Hurt, Ruby Ray, Stephen Falk, Andrew Bateman, Tom Crosby, Sarah Gwynne, Ricky A. Sharma, Somnath Mukherjee, Catrin Cox, Ganesh Radhakrishna, David Sebag-Montefiore, Joanne Canham, Heike I. Grabsch, Nick Maynard
Publikováno v:
European Journal of Cancer
European Journal of Cancer, 153, 153-161. ELSEVIER SCI LTD
European Journal of Cancer, 153, 153-161. ELSEVIER SCI LTD
Aim This is the first randomised study to evaluate toxicity and survival outcomes of two neoadjuvant chemoradiotherapy (CRT) regimens for patients with localised oesophageal adenocarcinoma (OAC) or gastro-oesophageal junction (GOJ) adenocarcinoma. Th
Autor:
Annie Keane, Tom Crosby, Kate Cleary, Olivier Joseph, Ganesh Radhakrishna, Maria A. Hawkins, Sue Campbell, Sarah Gwynne, O. Nicholas
Publikováno v:
The Patient - Patient-Centered Outcomes Research. 14:545-553
Neoadjuvant chemoradiotherapy for oesophageal cancer significantly improves overall survival but is associated with severe post-operative complications. Proton beam therapy may reduce these toxicities by sparing normal tissues compared with standard
Autor:
Richard Webster, Tom Crosby, Sarah Gwynne, A. Selby, C. Bowden, O. Nicholas, Paul D. Lewis, S. Mukherjee, Owen Bodger, Gareth Jones, Maria A. Hawkins, G. Radhakrishna
Publikováno v:
Clinical Oncology. 32:828-834
Aims NeoSCOPE is a trial of two different neoadjuvant chemoradiotherapy regimens for resectable oesophageal cancer and was the first multicentre trial in the UK to incorporate four-dimensional computed tomography (4D-CT) into radiotherapy planning. D
Autor:
Mutahar Ali Tunio, Craig Barrington, Mau-Don Phan, Sarah Gwynne, Mark Davies, Rhiannon Harries
Publikováno v:
Clinical Oncology. 34:e18