Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sarah Gourmaud"'
Autor:
He N. Xu, Sarah Gourmaud, Allison Podsednik, Xiaofan Li, Huaqing Zhao, Frances E. Jensen, Delia M. Talos, Lin Z. Li
Publikováno v:
Metabolites, Vol 12, Iss 9, p 786 (2022)
A substantial decline in nicotinamide adenine dinucleotide (NAD) has been reported in brain tissue homogenates or neurons isolated from Alzheimer’s disease (AD) models. NAD, together with flavin adenine dinucleotide (FAD), critically supports energ
Externí odkaz:
https://doaj.org/article/231181e9199b4118863cc56773f60861
Autor:
Mariko Taga, François Mouton-Liger, Malha Sadoune, Sarah Gourmaud, Jenny Norman, Marion Tible, Sylvie Thomasseau, Claire Paquet, James A R Nicoll, Delphine Boche, Jacques Hugon
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196983 (2018)
Metabolic disorders including obesity and type 2 diabetes are known to be associated with chronic inflammation and are obvious risk factors for Alzheimer's disease. Recent evidences concerning obesity and diabetes suggest that the metabolic inflammas
Externí odkaz:
https://doaj.org/article/3fccf4e192db43d19c9a1d347149f352
Autor:
Leah M. Jacobs, Frances E. Jensen, Kimberly Sansalone, David J. Irwin, Delia M. Talos, Sarah Gourmaud, Eric D. Marsh, Kathryn A. Davis, Haochang Shou, Timothy H. Lucas
Publikováno v:
Brain
Temporal lobe epilepsy represents a major cause of drug-resistant epilepsy. Cognitive impairment is a frequent comorbidity, but the mechanisms are not fully elucidated. We hypothesized that the cognitive impairment in drug-resistant temporal lobe epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38153b1b6de865f9f62e01cd6d4a7ebb
https://doi.org/10.1093/brain/awz381
https://doi.org/10.1093/brain/awz381
Autor:
Aaron J Barbour, David J. Irwin, Grace Eberwine, Sarah Gourmaud, Frances E. Jensen, Delia M. Talos, Robert Vassar, Nicholas Roberts, William T. O'Brien, David Andrew Stewart
Publikováno v:
Brain : a journal of neurology. 145(1)
The risk of seizures is 10-fold higher in patients with Alzheimer’s disease than the general population, yet the mechanisms underlying this susceptibility and the effects of these seizures are poorly understood. To elucidate the proposed bidirectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c89e339ab7fa4739470687d3cc4934
https://pubmed.ncbi.nlm.nih.gov/35277718
https://pubmed.ncbi.nlm.nih.gov/35277718
Autor:
Jacques Hugon, Claire Paquet, Sarah Gourmaud, Claire Abadie, Sylvie Thomasseau, Priscilla Thomas, Marion Tible
Publikováno v:
Journal of Alzheimer's Disease. 63:665-674
Alzheimer's disease (AD) is characterized by accumulations of amyloid-β (Aβ42) and hyperphosphorylated tau proteins, associated with neuroinflammation, synaptic loss, and neuronal death. Several studies indicate that c-Jun N-terminal kinase (JNK) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c9921d4f366a2871f022cddd86aef6
https://doi.org/10.3233/jad-171099
https://doi.org/10.3233/jad-171099
Autor:
Kathryn A. Davis, Sarah Gourmaud, Timothy H. Lucas, Leah M. Jacobs, Carlos A. Coto, Kuei-Cheng Lim, Delia M. Talos, Frances E. Jensen, Maria Martinez-Lage, Hongyu Sun
Publikováno v:
Annals of Neurology. 83:311-327
OBJECTIVE Temporal lobe epilepsy (TLE) is a chronic epilepsy syndrome defined by seizures and progressive neurological disabilities, including cognitive impairments, anxiety, and depression. Here, human TLE specimens were investigated focusing on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::542bd76ee34e012daa61b396ccfc2066
https://doi.org/10.1002/ana.25149
https://doi.org/10.1002/ana.25149
Autor:
François Mouton-Liger, Claire Paquet, Jacques Hugon, Claire Abadie, Sarah Gourmaud, Eliane F. Meurs
Publikováno v:
Journal of Alzheimer's Disease. 54:1659-1670
In Alzheimer's disease (AD), the amyloid cascade hypothesis proposes that amyloid-beta (Aβ) neurotoxicity leads to neuroinflammation, synaptic loss, and neuronal degeneration. In AD patients, anti-amyloid immunotherapies did not succeed because they
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e666325aad87fe7797d1aad1ad37b530
https://doi.org/10.3233/jad-160509
https://doi.org/10.3233/jad-160509
Autor:
Sarah Gourmaud, James A. R. Nicoll, Malha Sadoune, Jacques Hugon, Mariko Taga, Sylvie Thomasseau, Marion Tible, Jenny Norman, Claire Paquet, François Mouton-Liger, Delphine Boche
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196983 (2018)
PLoS ONE
PLoS ONE
Metabolic disorders including obesity and type 2 diabetes are known to be associated with chronic inflammation and are obvious risk factors for Alzheimer’s disease. Recent evidences concerning obesity and diabetes suggest that the metabolic inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19495bd9bbd87c07c5ae1dbea48e97d
http://europepmc.org/articles/PMC5968403?pdf=render
http://europepmc.org/articles/PMC5968403?pdf=render
Autor:
Sarah Gourmaud, Jacques Hugon, Clarisse Pace, Constantin Bouras, Françoise Gray, Julien Dumurgier, Jean-Louis Laplanche, Eliane F. Meurs, Claire Paquet, François Mouton-Liger
Publikováno v:
Journal of Psychiatry and Neuroscience. 40:151-161
Background: Alzheimer disease is characterized by cognitive decline, senile plaques of β-amyloid (Aβ) peptides, neurofibrillary tangles composed of hyperphosphorylated τ proteins and neuronal loss. Aβ and τ are useful markers in the cerebrospina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4241fa744aa5e58a697dc4fe77a2d275
https://doi.org/10.1503/jpn.140062
https://doi.org/10.1503/jpn.140062
Autor:
Claire Paquet, Delphine Boche, Anne Janin, Guilhem Bousquet, Morad El Bouchtaoui, Sarah Gourmaud
Publikováno v:
Neuropathology. 37:91-93
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30034f13bf34d1c3728ca083038c0f64
https://doi.org/10.1111/neup.12323
https://doi.org/10.1111/neup.12323