Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Sarah Gold"'
Autor:
Sarah Gold, BA, Christina Huang, BS, Rakan Radi, MD, Pranav Gupta, MBBS, Eric I. Felner, MD, MS, Jeehea Sonya Haw, MD, Krista Childress, MD, Nancy Sokkary, MD, Vin Tangpricha, MD, PhD, Michael Goodman, MD, MPH, Howa Yeung, MD, MSc
Publikováno v:
International Journal of Women's Dermatology, Vol 9, Iss 3, p e106 (2023)
Background:. Differences of sex development (DSD or disorders of sex development) are uncommon congenital conditions, characterized by atypical development of chromosomal, gonadal, or anatomic sex. Objective:. Dermatologic care is an important compon
Externí odkaz:
https://doaj.org/article/fd123ebd3e3747e6adb3b34a5fdb9ac9
Autor:
Lili Li, Meiling Gao, Jie Li, Xuping Xie, Hui Zhao, Yanan Wang, Xin Xu, Shulong Zu, Chunfeng Chen, Dingyi Wan, Jing Duan, Jingfeng Wang, Saba R. Aliyari, Sarah Gold, Jicai Zhang, Cheng-Feng Qin, Pei-Yong Shi, Heng Yang, Genhong Cheng
Publikováno v:
EBioMedicine, Vol 87, Iss , Pp 104401- (2023)
Summary: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the global coronavirus disease 2019 (COVID-19) pandemic, contains a unique, four amino acid (aa) “PRRA” insertion in the spike (S) protein t
Externí odkaz:
https://doaj.org/article/d6247f0c099b48f4b49d012bbd677740
Autor:
Joseph C Ward, Lidia Lasecka-Dykes, Chris Neil, Oluwapelumi O Adeyemi, Sarah Gold, Niall McLean-Pell, Caroline Wright, Morgan R Herod, David Kealy, Emma Warner, Terry Jackson, Donald P King, Tobias J Tuthill, David J Rowlands, Nicola J Stonehouse
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010589 (2022)
Non-coding regions of viral RNA (vRNA) genomes are critically important in the regulation of gene expression. In particular, pseudoknot (PK) structures, which are present in a wide range of RNA molecules, have a variety of roles. The 5' untranslated
Externí odkaz:
https://doaj.org/article/8c98451b274449f58dae2fd9d06a9bcd
Autor:
Lidia Lasecka-Dykes, Fiona Tulloch, Peter Simmonds, Garry A. Luke, Paolo Ribeca, Sarah Gold, Nick J. Knowles, Caroline F. Wright, Jemma Wadsworth, Mehreen Azhar, Donald P. King, Tobias J. Tuthill, Terry Jackson, Martin D. Ryan
Publikováno v:
mSphere, Vol 6, Iss 4 (2021)
Some RNA structures formed by the genomes of RNA viruses are critical for viral replication. Our study shows that of 46 conserved RNA structures located within the regions of the foot-and-mouth disease virus (FMDV) genome that encode the nonstructura
Externí odkaz:
https://doaj.org/article/10ab9e2361ee4beeb6c7650dd1ec484e
Autor:
Nina Sun, Chunfeng Li, Xiao-Feng Li, Yong-Qiang Deng, Tao Jiang, Na-Na Zhang, Shulong Zu, Rong-Rong Zhang, Lili Li, Xiang Chen, Ping Liu, Sarah Gold, Ning Lu, Peishuang Du, Jingfeng Wang, Cheng-Feng Qin, Genhong Cheng
Publikováno v:
Cell Reports, Vol 33, Iss 5, Pp 108342- (2020)
Summary: Influenza A virus (IAV) infection stimulates a type I interferon (IFN-I) response in host cells that exerts antiviral effects by inducing the expression of hundreds of IFN-stimulated genes (ISGs). However, most ISGs are poorly studied for th
Externí odkaz:
https://doaj.org/article/055d815fdcd045f9bdf0a1d1abf381ad
Autor:
Gareth Shimmon, Abhay Kotecha, Jingshan Ren, Amin S Asfor, Joseph Newman, Stephen Berryman, Eleanor M Cottam, Sarah Gold, Toby J Tuthill, Donald P King, Emiliana Brocchi, Andrew M Q King, Ray Owens, Elizabeth E Fry, David I Stuart, Alison Burman, Terry Jackson
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201853 (2018)
Foot-and-mouth disease (FMD) affects economically important livestock and is one of the most contagious viral diseases. The most commonly used FMD diagnostic assay is a sandwich ELISA. However, the main disadvantage of this ELISA is that it requires
Externí odkaz:
https://doaj.org/article/af497286ece043398ed1c76b8d22136a
Autor:
Morgan R Herod, Sarah Gold, Lidia Lasecka-Dykes, Caroline Wright, Joseph C Ward, Thomas C McLean, Sophie Forrest, Terry Jackson, Tobias J Tuthill, David J Rowlands, Nicola J Stonehouse
Publikováno v:
PLoS Pathogens, Vol 13, Iss 10, p e1006666 (2017)
The RNA genomes of picornaviruses are translated into single polyproteins which are subsequently cleaved into structural and non-structural protein products. For genetic economy, proteins and processing intermediates have evolved to perform distinct
Externí odkaz:
https://doaj.org/article/f00aa72db3d24648882e712bc8e4d3ea
Autor:
Nayab Malik, Abhay Kotecha, Sarah Gold, Amin Asfor, Jingshan Ren, Juha T Huiskonen, Tobias J Tuthill, Elizabeth E Fry, David I Stuart
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006607 (2017)
Foot-and-mouth disease virus (FMDV) belongs to the Aphthovirus genus of the Picornaviridae, a family of small, icosahedral, non-enveloped, single-stranded RNA viruses. It is a highly infectious pathogen and is one of the biggest hindrances to the int
Externí odkaz:
https://doaj.org/article/2489ccc75fb848c19048fd8c378c778d
Autor:
Elisabetta Groppelli, Hazel C Levy, Eileen Sun, Mike Strauss, Clare Nicol, Sarah Gold, Xiaowei Zhuang, Tobias J Tuthill, James M Hogle, David J Rowlands
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006197 (2017)
Picornaviruses are non-enveloped RNA viruses that enter cells via receptor-mediated endocytosis. Because they lack an envelope, picornaviruses face the challenge of delivering their RNA genomes across the membrane of the endocytic vesicle into the cy
Externí odkaz:
https://doaj.org/article/319e73edff604deca97edacbdc918568
Autor:
Anusha Panjwani, Mike Strauss, Sarah Gold, Hannah Wenham, Terry Jackson, James J Chou, David J Rowlands, Nicola J Stonehouse, James M Hogle, Tobias J Tuthill
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004294 (2014)
Non-enveloped viruses must deliver their viral genome across a cell membrane without the advantage of membrane fusion. The mechanisms used to achieve this remain poorly understood. Human rhinovirus, a frequent cause of the common cold, is a non-envel
Externí odkaz:
https://doaj.org/article/240f4074114e4f3b884aa622f49c189a