Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sarah Glewis"'
Autor:
Sarah Glewis, Mei Krishnasamy, Senthil Lingaratnam, Sam Harris, Craig Underhill, Chloe Georgiou, Mark Warren, Robert Campbell, Maarten IJzerman, Mussab Fagery, Ian Campbell, Jennifer H. Martin, Jeanne Tie, Marliese Alexander, Michael Michael
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 12, Pp 2700-2708 (2023)
Abstract This study explored the acceptability of a novel pharmacist‐led pharmacogenetics (PGx) screening program among patients with cancer and healthcare professionals (HCPs) taking part in a multicenter clinical trial of PGx testing (PACIFIC‐P
Externí odkaz:
https://doaj.org/article/4034bb7ba4d84e32bda0fff26aa22e13
Autor:
Sarah Glewis, Marliese Alexander, Senthil Lingaratnam, Benjamin Lee, Ian Campbell, Mei Krishnasamy, Maarten IJzerman, Mussab Fagery, Sam Harris, Chloe Georgiou, Craig Underhill, Mark Warren, Robert Campbell, Jennifer Martin, Jeanne Tie, Michael Michael
Publikováno v:
Acta Oncologica. 61:1136-1139
Pharmacogenomics guided dosing for fluoropyrimidine and irinotecan chemotherapies for patients with cancer (PACIFIC-PGx): study protocol of a multicentre clinical trial
Autor:
Sarah Glewis, Marliese Alexander, Muhammad N. H. Khabib, Annabelle Brennan, Smaro Lazarakis, Jennifer Martin, Jeanne Tie, Senthil Lingaratnam, Michael Michael
Publikováno v:
Br J Cancer
BACKGROUND: Serious and potentially life-threatening toxicities can occur following 5-fluorouracil/capecitabine exposure. Patients carrying Dihydropyrimidine Dehydrogenase (DPYD) variant alleles associated with decreased enzymatic function are at a g
Autor:
Sarah Glewis, Senthil Lingaratnam, Mei Krishnasamy, Jennifer H Martin, Jeanne Tie, Marliese Alexander, Michael Michael
Publikováno v:
Journal of Oncology Pharmacy Practice. :107815522311675
Background Despite robust evidence and international guidelines, to support routine pharmacogenetic (PGx) testing, integration in practice has been limited. This study explored clinicians’ views and experiences of pre-treatment DPYD and UGT1A1 gene
Autor:
Sam Maleki, Sarah Glewis, Tsien Fua, Chen Liu, Danny Rischin, Marliese Alexander, Lumine Na, Senthil Lingaratnam
Publikováno v:
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 30(5)
Patient understanding of medicines information and adherence to medication instructions are important variables for ensuring optimal cancer care. This randomised controlled trial (RCT) aimed to evaluate the impact of an outpatient clinical pharmacy s
Autor:
Antoine Sedrak, Karen Luetsch, Marliese Alexander, Cherie Chiang, Sarah Glewis, Senthil Lingaratnam
Publikováno v:
Research in socialadministrative pharmacy : RSAP. 17(3)
Background Patients diagnosed with cancer are often treated with high dose glucocorticosteroids, increasing their risk of developing hyperglycaemia or steroid-induced diabetes, which can be reduced by regular monitoring of blood glucose levels. Commu
Autor:
Marliese Alexander, Hui-Li Wong, Michael Michael, Michael Jefford, Benjamin Lee, Prudence A. Francis, Sarah Glewis, Jeanne Tie, Danny Rischin, Senthil Lingaratnam
Publikováno v:
Journal of Clinical Oncology. 39:e18644-e18644
e18644 Background: Polymorphisms in the DPYD gene, which encodes for dihydropyrimidine dehydrogenase (DPD), may impair DPD metabolism of fluoropyrimidines (FP) and cause life-threatening toxicities. The European Medicines Agency (EMA) recommend testi