Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sarah Gillaspie"'
Autor:
Chingakham Ranjit Singh, M. Rebecca Glineburg, Chelsea Moore, Naoki Tani, Rahul Jaiswal, Ye Zou, Eric Aube, Sarah Gillaspie, Mackenzie Thornton, Ariana Cecil, Madelyn Hilgers, Azuma Takasu, Izumi Asano, Masayo Asano, Carlos R. Escalante, Akira Nakamura, Peter K. Todd, Katsura Asano
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109376- (2021)
Summary: eIF5-mimic protein (5MP) is a translational regulatory protein that binds the small ribosomal subunit and modulates its activity. 5MP is proposed to reprogram non-AUG translation rates for oncogenes in cancer, but its role in controlling non
Externí odkaz:
https://doaj.org/article/5cad839a14af4e99972d37594a69c639
Autor:
Kuniaki Sato, Takaaki Masuda, Qingjiang Hu, Taro Tobo, Sarah Gillaspie, Atsushi Niida, Mackenzie Thornton, Yousuke Kuroda, Hidetoshi Eguchi, Takashi Nakagawa, Katsura Asano, Koshi Mimori
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 387-402 (2019)
Background: Translational reprogramming through controlled initiation from non-AUG start codons is considered a crucial driving force in tumorigenesis and tumor progression. However, its clinical impact and underlying mechanism are not fully understo
Externí odkaz:
https://doaj.org/article/2de3a6e8311344458ad956e83ed0a466
Autor:
Chelsea Moore, Madelyn Hilgers, Ariana Cecil, Naoki Tani, Akira Nakamura, Katsura Asano, Ye Zou, Rahul Jaiswal, Peter K. Todd, Chingakham Ranjit Singh, Masayo Asano, Sarah Gillaspie, Eric Aube, Izumi Asano, Mackenzie M. Thornton, Azuma Takasu, M. Rebecca Glineburg, Carlos R. Escalante
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109376-(2021)
Cell Rep
Cell Rep
Summary: eIF5-mimic protein (5MP) is a translational regulatory protein that binds the small ribosomal subunit and modulates its activity. 5MP is proposed to reprogram non-AUG translation rates for oncogenes in cancer, but its role in controlling non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650144f6f97c402de64bec1f59bb7541
http://www.sciencedirect.com/science/article/pii/S2211124721007749
http://www.sciencedirect.com/science/article/pii/S2211124721007749
Autor:
Atsushi Niida, Katsura Asano, Sarah Gillaspie, Mackenzie M. Thornton, Takashi Nakagawa, Hidetoshi Eguchi, Koshi Mimori, Qingjiang Hu, Taro Tobo, Kuniaki Sato, Yousuke Kuroda, Takaaki Masuda
Background Translational reprogramming through controlled initiation from non-AUG start codons is considered a crucial driving force in tumorigenesis and tumor progression. However, its clinical impact and underlying mechanism are not fully understoo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b094215c01e6a3886c8fb0d804bbf318
https://europepmc.org/articles/PMC6606960/
https://europepmc.org/articles/PMC6606960/
Autor:
Abbey Anderson, Masayo Asano, Sarah Gillaspie, Ken-ichi Yoshino, Megan Reid, Brytteny Thompson, Gerhard Wagner, Stefan Rothenburg, Chingakham Ranjit Singh, Hisao Masai, Rafael E. Luna, Jerome C. Nietfeld, Alexander Beeser, Hideaki Tagami, Samantha Hustak, Sherry D. Fleming, Hiroyuki Hiraishi, Christian Cox, Akio Nakashima, J.-P. Perchellet, Emily Archer Slone, Caitlin Kozel, Ushio Kikkawa, Katsura Asano, Evangelos Papadopoulos, Chelsea Moore
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 44, iss 18
Nucleic acids research, vol 44, iss 18
ATF4 is a pro-oncogenic transcription factor whose translation is activated by eIF2 phosphorylation through delayed re-initiation involving two uORFs in the mRNA leader. However, in yeast, the effect of eIF2 phosphorylation can be mimicked by eIF5 ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b967ed7ab95a71076403b3e6554978c6
http://europepmc.org/articles/PMC5062967
http://europepmc.org/articles/PMC5062967
Autor:
Chingakham Ranjit Singh, Leiming Tang, Abbey Anderson, Ji Wan, Jacob Morris, Jagpreet S. Nanda, Eric Aube, Hiroyuki Hiraishi, Maud Marques, Leiming Dong, Chelsea Moore, Michael Witcher, Maika Jangal, Shu-Bing Qian, Katsura Asano, Hirohide Saito, Sarah Gillaspie, Ivan Topisirovic, Christian Cox, Yoshihiko Fujita
Publikováno v:
Nucleic Acids Research
In the human genome, translation initiation from non-AUG codons plays an important role in various gene regulation programs. However, mechanisms regulating the non-AUG initiation rate remain poorly understood. Here, we show that the non-AUG initiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b4afcf8b0f87c0a1925167ad924410
https://pubmed.ncbi.nlm.nih.gov/28981728
https://pubmed.ncbi.nlm.nih.gov/28981728
Autor:
Chingakham Ranjit Singh, Katsura Asano, Sarah Gillaspie, Shu-Bing Qian, Abbey Anderson, Ji Wan, Eric Aube, Ivan Topisirovic, Chelsea Moore, Michael Witcher
Publikováno v:
Cancer Research. 77:A12-A12
In eukaryotic translation initiation, both the m7G-capped mRNA and the small ribosomal subunit (SSU) are activated through eukaryotic initiation factors bound to Met-tRNAIMet, which allows formation of the 48S ribosome pre-initiation complex (PIC) wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::795fbac58acbd5eb415a9faae15dcba7
https://doi.org/10.1158/1538-7445.transcontrol16-a12
https://doi.org/10.1158/1538-7445.transcontrol16-a12