Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Sarah Gerlo"'
Autor:
Jozefien De Clercq, Marie-Angélique De Scheerder, Sophie Vanherrewege, Els Caluwé, Nathalie Moreels, Danny Delooze, Annemieke Dhondt, Marc Coppens, Stefaan J. Vandecasteele, Sabine D. Allard, Coca Necsoi, Stéphane De Wit, Sarah Gerlo, Linos Vandekerckhove
Publikováno v:
Journal of Virus Eradication, Vol 10, Iss 3, Pp 100392- (2024)
Background: The events during acute HIV infection (AHI) set the stage for the subsequent course of the disease. Early initiation of antiretroviral therapy (ART) has been associated with favorable immunovirological outcomes, yet the precise impact of
Externí odkaz:
https://doaj.org/article/c7fb9b05746642adbee12a5ccc8b7cb0
Autor:
Delphine Diana Acar, Wojciech Witkowski, Magdalena Wejda, Ruifang Wei, Tim Desmet, Bert Schepens, Sieglinde De Cae, Koen Sedeyn, Hannah Eeckhaut, Daria Fijalkowska, Kenny Roose, Sandrine Vanmarcke, Anne Poupon, Dirk Jochmans, Xin Zhang, Rana Abdelnabi, Caroline S. Foo, Birgit Weynand, Dirk Reiter, Nico Callewaert, Han Remaut, Johan Neyts, Xavier Saelens, Sarah Gerlo, Linos Vandekerckhove
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104960- (2024)
Summary: Background: SARS-CoV-2-neutralizing antibodies (nABs) showed great promise in the early phases of the COVID-19 pandemic. The emergence of resistant strains, however, quickly rendered the majority of clinically approved nABs ineffective. This
Externí odkaz:
https://doaj.org/article/d61b439c0eca42cfae0b6e3405d320a1
Autor:
Jozefien De Clercq, Marie-Angélique De Scheerder, Virginie Mortier, Chris Verhofstede, Stefaan J. Vandecasteele, Sabine D. Allard, Coca Necsoi, Stéphane De Wit, Sarah Gerlo, Linos Vandekerckhove
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundDespite the beneficial effects of antiretroviral therapy (ART) initiation during acute HIV infection (AHI), residual immune activation remains a hallmark of treated HIV infection.MethodsPlasma concentrations of 40 mediators were measured lo
Externí odkaz:
https://doaj.org/article/bf29fbebcf7e4ae69d0b09795c182563
Autor:
Bram Van Den Eeckhout, Marlies Ballegeer, Jozefien De Clercq, Elianne Burg, Xavier Saelens, Linos Vandekerckhove, Sarah Gerlo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15770 (2023)
IL-1R integrates signals from IL-1α and IL-1β, and it is widely expressed across tissues and immune cell types. While the expression pattern and function of IL-1R within the innate immune system is well studied, its role in adaptive immunity, parti
Externí odkaz:
https://doaj.org/article/156ce21a434b42feb713b538afc44d85
Autor:
Jolien Van Cleemput, Willem van Snippenberg, Laurens Lambrechts, Amélie Dendooven, Valentino D’Onofrio, Liesbeth Couck, Wim Trypsteen, Jan Vanrusselt, Sebastiaan Theuns, Nick Vereecke, Thierry P. P. van den Bosch, Martin Lammens, Ann Driessen, Ruth Achten, Ken R. Bracke, Wim Van den Broeck, Jan Von der Thüsen, Hans Nauwynck, Jo Van Dorpe, Sarah Gerlo, Piet Maes, Janneke Cox, Linos Vandekerckhove
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Here the authors provide a detailed virological analysis of thirteen postmortem COVID-19 cases, including presence of replication-competent SARS-CoV-2 in extrapulmonary organs and tissue-specific patterns of SARS-CoV-2 genome diversity of an immunoco
Externí odkaz:
https://doaj.org/article/d7ddc26aed524990a6ce3aa009110d7b
Autor:
Magdalena Sips, Sarah Gerlo, Laura De Clercq, Esteban A. Gomez, Romain A. Colas, Jesmond Dalli, Linos Vandekerckhove
Publikováno v:
Immunity, Inflammation and Disease, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract Introduction: To date, with no prophylactic human immunodeficiency virus (HIV) vaccine available, HIV incidence rates remain undefeated. Despite full virological suppression, HIV+ individuals exhibit a higher rate of cardiovascular disorders
Externí odkaz:
https://doaj.org/article/bb8a17d4101f4c3cb52dad01a8588d6a
Autor:
Bram Van Den Eeckhout, Leander Huyghe, Sandra Van Lint, Elianne Burg, Stéphane Plaisance, Frank Peelman, Anje Cauwels, Gilles Uzé, Niko Kley, Sarah Gerlo, Jan Tavernier
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/d36241b88658437b966c5cf4b40f4553
Autor:
Jolien Van Cleemput, Willem van Snippenberg, Laurens Lambrechts, Amélie Dendooven, Valentino D’Onofrio, Liesbeth Couck, Wim Trypsteen, Jan Vanrusselt, Sebastiaan Theuns, Nick Vereecke, Thierry P. P. van den Bosch, Martin Lammens, Ann Driessen, Ruth Achten, Ken R. Bracke, Wim Van den Broeck, Jan Von der Thüsen, Hans Nauwynck, Jo Van Dorpe, Sarah Gerlo, Piet Maes, Janneke Cox, Linos Vandekerckhove
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/9f77ef830b194c9b9a8e8fd6596e4eaf
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
The three-signal paradigm tries to capture how the innate immune system instructs adaptive immune responses in three well-defined actions: (1) presentation of antigenic peptides in the context of MHC molecules, which allows for a specific T cell resp
Externí odkaz:
https://doaj.org/article/5dcb4c29975e4a7d942bd5f443baa384
Autor:
Wojciech Witkowski, Sarah Gerlo, Evelien De Smet, Magdalena Wejda, Delphine Acar, Steven Callens, Stefan Heytens, Elizaveta Padalko, Hanne Vercruysse, Piet Cools, Linos Vandekerckhove
Publikováno v:
Vaccines, Vol 10, Iss 2, p 260 (2022)
Despite the high efficacy of the BNT162b2 vaccine in the general population, data on its immunogenicity among frail elderly individuals are limited. Recently, levels of anti-SARS-CoV-2 spike IgG antibodies and serum neutralization titers were confirm
Externí odkaz:
https://doaj.org/article/6a156e6f19be4d06b35559162ea215d2