Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sarah Geisler"'
Autor:
Rachelle Driscoll, Lucas Hampton, Neeta A. Abraham, J. Douglas Larigan, Nadine F. Joseph, Juan C. Hernandez-Vega, Sarah Geisler, Fu-Chia Yang, Matthew Deninger, David T. Tran, Natasha Khatri, Bruno M. D. C. Godinho, Garth A. Kinberger, Daniel R. Montagna, Warren D. Hirst, Catherine L. Guardado, Kelly E. Glajch, H. Moore Arnold, Corrie L. Gallant-Behm, Andreas Weihofen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Huntington's disease (HD) is a progressive neurodegenerative disorder caused by CAG trinucleotide repeat expansions in exon 1 of the HTT gene. In addition to germline CAG expansions, somatic repeat expansions in neurons also contribute to HD
Externí odkaz:
https://doaj.org/article/708fdef928c448a8ad36da3b5a637de6
Autor:
Kathleen M McAvoy, Hameetha Rajamohamed Sait, Galina Marsh, Michael Peterson, Taylor L Reynolds, Jake Gagnon, Sarah Geisler, Prescott Leach, Chris Roberts, Ellen Cahir-McFarland, Richard M Ransohoff, Andrea Crotti
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220125 (2019)
BIN1 is the most important risk locus for Late Onset Alzheimer's Disease (LOAD), after ApoE. BIN1 AD-associated SNPs correlate with Tau deposition as well as with brain atrophy. Furthermore, the level of neuronal-specific BIN1 isoform 1 protein is de
Externí odkaz:
https://doaj.org/article/b219eafc69c04bee8793168a9f96f48d
Autor:
Jenna E. Smith, Juan R. Alvarez-Dominguez, Nicholas Kline, Nathan J. Huynh, Sarah Geisler, Wenqian Hu, Jeff Coller, Kristian E. Baker
Publikováno v:
Cell Reports, Vol 7, Iss 6, Pp 1858-1866 (2014)
High-throughput gene expression analysis has revealed a plethora of previously undetected transcripts in eukaryotic cells. In this study, we investigate >1,100 unannotated transcripts in yeast predicted to lack protein-coding capacity. We show that a
Externí odkaz:
https://doaj.org/article/7aa099a3fc3b41aabeb2f83b1e44b314
Autor:
Sarah Geisler
Publikováno v:
Cell. 174:1329-1331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b5b6405012c126fb326d8e1c6854b4
https://doi.org/10.1016/j.cell.2018.08.051
https://doi.org/10.1016/j.cell.2018.08.051
Autor:
Sarah Geisler
Publikováno v:
Cell. 173:1059-1061
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b8cb75b9e8e582683839f1f7a4cd92
https://doi.org/10.1016/j.cell.2018.05.001
https://doi.org/10.1016/j.cell.2018.05.001
Autor:
Sarah Geisler
Publikováno v:
Cell. 170(5)
Imagine a world where desirable traits are easily programmable. Farmers can select to grow plant varieties that both surprise and delight even the most sophisticated taste buds. Nutrient content and crop yields are improved to fight hunger and malnut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5a0bf94389705b236b193e697a53f2
https://pubmed.ncbi.nlm.nih.gov/28841412
https://pubmed.ncbi.nlm.nih.gov/28841412
Autor:
Jake Gagnon, Michael Peterson, Prescott Leach, Chris Roberts, Andrea Crotti, Hameetha Banu Rajamohamed Sait, Galina Marsh, Taylor L. Reynolds, Sarah Geisler, Kathleen M. McAvoy, Richard M. Ransohoff, Ellen Cahir-McFarland
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220125 (2019)
PLoS ONE
PLoS ONE
BIN1 is the most important risk locus for Late Onset Alzheimer’s Disease (LOAD), after ApoE. BIN1 AD-associated SNPs correlate with Tau deposition as well as with brain atrophy. Furthermore, the level of neuronal-specific BIN1 isoform 1 protein is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059b4e092493e6e0cb6d7a8bbf2b31d6
https://doi.org/10.1371/journal.pone.0220125
https://doi.org/10.1371/journal.pone.0220125
Autor:
Richard M. Ransohoff, Galina Marsh, Taylor L. Reynolds, Andrea Crotti, Michael Peterson, Chris Roberts, Jake Gagnon, Hameetha Banu Rajamohamed Sait, Sarah Geisler, Kathleen M. McAvoy
Publikováno v:
Alzheimer's & Dementia. 15:P285-P285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::309f9a7c494987189fa486647fa67107
https://doi.org/10.1016/j.jalz.2019.06.684
https://doi.org/10.1016/j.jalz.2019.06.684
Autor:
Sarah, Geisler
Publikováno v:
Cell. 178:511
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3dfc823abf90a41fb6c51a689513100
https://doi.org/10.1016/j.cell.2019.07.003
https://doi.org/10.1016/j.cell.2019.07.003
Autor:
Sarah Geisler, Jeff Coller
Publikováno v:
Nature Reviews Molecular Cell Biology. 14:699-712
The increased application of transcriptome-wide profiling approaches has led to an explosion in the number of documented long non-coding RNAs (lncRNAs). While these new and enigmatic players in the complex transcriptional milieu are encoded by a sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b6f27513ae7b10bca84d901052dbd2
https://doi.org/10.1038/nrm3679
https://doi.org/10.1038/nrm3679