Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sarah G. Whaley"'
Autor:
Sarah G. Whaley, Kelly E. Caudle, Lucia Simonicova, Qing Zhang, W. Scott Moye-Rowley, P. David Rogers
Publikováno v:
mSphere, Vol 3, Iss 1 (2018)
ABSTRACT The high prevalence of fluconazole resistance among clinical isolates of Candida glabrata has greatly hampered the utility of fluconazole for the treatment of invasive candidiasis. Fluconazole resistance in this yeast is almost exclusively d
Externí odkaz:
https://doaj.org/article/29a87add80ba496aa18e8316ed68c869
Autor:
Munhyung Bae, David R. Andes, Cameron R. Currie, Sarah G. Whaley, Gleb Pishchany, Emily Mevers, Charles O. Rock, Jon Clardy, Mônica Tallarico Pupo
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Org Lett
Universidade de São Paulo (USP)
instacron:USP
Org Lett
Herein is a report on the molecular exchange occurring between multilateral symbiosis partners – a tit-for-tat exchange that led to the characterization of two new metabolites, conocandin B (fungal-derived) and dentigerumycin F (bacterial-derived).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac5ba69a50a16eb4bf32caa5435d8ab
https://doi.org/10.1021/acs.orglett.1c00068
https://doi.org/10.1021/acs.orglett.1c00068
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef758924c387a4c9495bee7a5b988d55
https://doi.org/10.1096/fasebj.2022.36.s1.r4125
https://doi.org/10.1096/fasebj.2022.36.s1.r4125
Publikováno v:
The Journal of Biological Chemistry
Bacterial fatty acid synthesis in Escherichia coli is initiated by the condensation of an acetyl-CoA with a malonyl-acyl carrier protein (ACP) by the β-ketoacyl-ACP synthase III enzyme, FabH. E. coli ΔfabH knockout strains are viable because of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403bca77b66efe2dad00899b24173d60
https://pubmed.ncbi.nlm.nih.gov/34801557
https://pubmed.ncbi.nlm.nih.gov/34801557
Autor:
Charles O. Rock, Sarah G. Whaley
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00daf2d5a582a1a5a329f359cf525d46
https://doi.org/10.1096/fasebj.2021.35.s1.03136
https://doi.org/10.1096/fasebj.2021.35.s1.03136
Autor:
Bivash Mandal, P. David Rogers, Dileep R. Janagam, George C. Wood, Pavan Balabathula, Sarah G. Whaley, Laura A. Thoma, Nivesh K. Mittal
Publikováno v:
Pharmaceutics
Volume 12
Issue 3
Pharmaceutics, Vol 12, Iss 3, p 247 (2020)
Volume 12
Issue 3
Pharmaceutics, Vol 12, Iss 3, p 247 (2020)
We formulated and tested a targeted nanodrug delivery system to help treat life-threatening invasive fungal infections, such as cryptococcal meningitis. Various designs of iron oxide nanoparticles (IONP) (34&ndash
40 nm) coated with bovine serum
40 nm) coated with bovine serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea7e7264e9adf63c3955e5f69c10903
Publikováno v:
The Journal of Biological Chemistry
Branched-chain amino acids (primarily isoleucine) are important regulators of virulence and are converted to precursor molecules used to initiate fatty acid synthesis in Staphylococcus aureus. Defining how bacteria control their membrane phospholipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236fe395a0a42b53733d52f9ba48e296
https://doi.org/10.1016/j.jbc.2021.101255
https://doi.org/10.1016/j.jbc.2021.101255
Autor:
Andrew T. Nishimoto, Edward P. Garvey, Sarah G. Whaley, Robert J. Schotzinger, Christopher M. Yates, P. David Rogers, William J. Hoekstra, Nathan P. Wiederhold, Qing Zhang
Publikováno v:
Antimicrobial agents and chemotherapy. 63(10)
VT-1161 and VT-1598 are promising investigational tetrazole antifungals that have shown in vitro and in vivo activity against Candida and other fungi. Candida glabrata is a problematic opportunistic pathogen that is associated with high mortality in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5045cc9547070ceb215a66698c6667
https://pubmed.ncbi.nlm.nih.gov/31383660
https://pubmed.ncbi.nlm.nih.gov/31383660
Publikováno v:
J Biol Chem
Oleate hydratases (OhyAs) belong to a large family of bacterial proteins catalyzing the hydration or isomerization of double bonds in unsaturated fatty acids. A Staphylococcus aureus gene (Sa0102) is predicted to encode an OhyA. Here, we recombinantl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aded6177a61844a0beab985b01ce6d54
https://pubmed.ncbi.nlm.nih.gov/31018965
https://pubmed.ncbi.nlm.nih.gov/31018965
Autor:
Sarah G. Whaley, Charles O. Rock
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fde4cd602896efc835a0747e34bf58f
https://doi.org/10.1096/fasebj.2020.34.s1.06665
https://doi.org/10.1096/fasebj.2020.34.s1.06665