Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sarah G. Injac"'
Autor:
Mari Kogiso, Lin Qi, Yuchen Du, Frank K. Braun, Huiyuan Zhang, L. Frank Huang, Lei Guo, Yulun Huang, Wan-Yee Teo, Holly Lindsay, Sibo Zhao, Sarah G. Injac, Zhen Liu, Vidya Mehta, Diep Tran, Feng Li, Patricia A. Baxter, Jack M. Su, Laszlo Perlaky, D. Williams Parsons, Murali Chintagumpala, Adekunle Adesina, Yongcheng Song, Xiao-Nan Li
Publikováno v:
Translational Oncology, Vol 18, Iss , Pp 101368- (2022)
Clinical outcomes in patients with WHO grade II/III astrocytoma, oligodendroglioma or secondary glioblastoma remain poor. Isocitrate dehydrogenase 1 (IDH1) is mutated in > 70% of these tumors, making it an attractive therapeutic target. To determine
Externí odkaz:
https://doaj.org/article/caa882369eb742c39053f6d150c8b83b
Autor:
Kim Linton, Francesco Forconi, David Lewis, John Riches, Dima El-Sharkawi, Mary Gleeson, Sarah G Injac, Srinand Nandakumar, May Tan, Ganesh Cherala, Graham P Collins
Publikováno v:
HemaSphere, Vol 7, p e593178d (2023)
Externí odkaz:
https://doaj.org/article/9acaa144c8144371b3f619cf6d905249
Autor:
Kim Linton, Jeanette Doorduijn, Dima El-Sharkawi, Rogier Mous, Francesco Forconi, David Lewis, Mary Gleeson, John Riches, Pam Mckay, Wendy Stevens, Sarah G Injac, Graham P Collins
Publikováno v:
HemaSphere, Vol 7, p e29005fd (2023)
Externí odkaz:
https://doaj.org/article/4fa81feb4baf430caea07404ff60ee9d
Autor:
Stephen C. Mack, Benjamin Deneen, Kelsey C. Bertrand, Claudia L. Kleinman, Nada Jabado, Joanna Yi, Richard J. Gilbertson, Sameer Agnihotri, Kristian W. Pajtler, Donald W. Parsons, Susan M. Blaney, Murali M. Chintagumpala, Thomas F. Westbrook, Irtisha Singh, H. Courtney Hodges, Charles Y. Lin, Stefan M. Pfister, Daisuke Kawauchi, Felix Sahm, Luz A. De León, Peter R. Wang, Madeline Ngo, Sarah G. Injac, Baoli Hu, Robert Kupp, Kathleen Kong, Kristen L. Karlin, Calla Olson, Yuen San Chan, Ann-Catherine J. Stanton, Brian J. Golbourn, Dana Tlais, Alisha Kardian, Minerva Solis, Austin J. Stuckert, Bryan Rivas, Selin Jessa, Hsiao-Chi Chen, Srinidhi Varadharajan, Yanhua Zhao, Amir Arabzade
93 gene signature that characterizes ZFTA-Rela mouse and human tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2455a45bb7a7160f6ff2e0c7dedb37da
https://doi.org/10.1158/2159-8290.22539655.v1
https://doi.org/10.1158/2159-8290.22539655.v1
Autor:
Stephen C. Mack, Benjamin Deneen, Kelsey C. Bertrand, Claudia L. Kleinman, Nada Jabado, Joanna Yi, Richard J. Gilbertson, Sameer Agnihotri, Kristian W. Pajtler, Donald W. Parsons, Susan M. Blaney, Murali M. Chintagumpala, Thomas F. Westbrook, Irtisha Singh, H. Courtney Hodges, Charles Y. Lin, Stefan M. Pfister, Daisuke Kawauchi, Felix Sahm, Luz A. De León, Peter R. Wang, Madeline Ngo, Sarah G. Injac, Baoli Hu, Robert Kupp, Kathleen Kong, Kristen L. Karlin, Calla Olson, Yuen San Chan, Ann-Catherine J. Stanton, Brian J. Golbourn, Dana Tlais, Alisha Kardian, Minerva Solis, Austin J. Stuckert, Bryan Rivas, Selin Jessa, Hsiao-Chi Chen, Srinidhi Varadharajan, Yanhua Zhao, Amir Arabzade
Figure S2 supporting expression and localization of ZRfus in the mouse IUE model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5100705dc6a0f49c6241a385bfa4fe37
https://doi.org/10.1158/2159-8290.22539676
https://doi.org/10.1158/2159-8290.22539676
Autor:
Stephen C. Mack, Benjamin Deneen, Kelsey C. Bertrand, Claudia L. Kleinman, Nada Jabado, Joanna Yi, Richard J. Gilbertson, Sameer Agnihotri, Kristian W. Pajtler, Donald W. Parsons, Susan M. Blaney, Murali M. Chintagumpala, Thomas F. Westbrook, Irtisha Singh, H. Courtney Hodges, Charles Y. Lin, Stefan M. Pfister, Daisuke Kawauchi, Felix Sahm, Luz A. De León, Peter R. Wang, Madeline Ngo, Sarah G. Injac, Baoli Hu, Robert Kupp, Kathleen Kong, Kristen L. Karlin, Calla Olson, Yuen San Chan, Ann-Catherine J. Stanton, Brian J. Golbourn, Dana Tlais, Alisha Kardian, Minerva Solis, Austin J. Stuckert, Bryan Rivas, Selin Jessa, Hsiao-Chi Chen, Srinidhi Varadharajan, Yanhua Zhao, Amir Arabzade
More than 60% of supratentorial ependymomas harbor a ZFTA–RELA (ZRfus) gene fusion (formerly C11orf95–RELA). To study the biology of ZRfus, we developed an autochthonous mouse tumor model using in utero electroporation (IUE) of the embryonic mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e3a974b88b13a244bee5e4ff38026e0
https://doi.org/10.1158/2159-8290.c.6549148.v1
https://doi.org/10.1158/2159-8290.c.6549148.v1
Autor:
Xiao-Nan Li, Jodi A. Muscal, Stacey Berg, Mark G. Qian, Debra Liao, Adekunle M. Adesina, Patricia A. Baxter, Jack M. Su, Holly Lindsay, Sibo Zhao, Frank Y. Lin, Huiyuan Zhang, Yuchen Du, Linna Zhang, Sarah G. Injac, Frank K. Braun, Lin Qi, Mari Kogiso
Purpose: Pediatric glioblastoma multiforme (pGBM) is a highly aggressive tumor in need of novel therapies. Our objective was to demonstrate the therapeutic efficacy of MLN8237 (alisertib), an orally available selective inhibitor of Aurora A kinase (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add973a53fa03709cc14fba8c29ebe20
https://doi.org/10.1158/1078-0432.c.6526046
https://doi.org/10.1158/1078-0432.c.6526046
Autor:
Xiao-Nan Li, Jodi A. Muscal, Stacey Berg, Mark G. Qian, Debra Liao, Adekunle M. Adesina, Patricia A. Baxter, Jack M. Su, Holly Lindsay, Sibo Zhao, Frank Y. Lin, Huiyuan Zhang, Yuchen Du, Linna Zhang, Sarah G. Injac, Frank K. Braun, Lin Qi, Mari Kogiso
Supplementary Figure S1-S3 Figure S1. Anti-proliferative effects of MLN8237 on pGBM cell lines. Paired monolayer (Mono) and neurosphere (NS) of IC-4687GBM, IC-3752GBM and ICR0315GBM were seeded at 2,000 cells/well and exposed to MLN8237 (1 - 4,000 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf825c071ffe844120a4e784048d90e
https://doi.org/10.1158/1078-0432.22465520.v1
https://doi.org/10.1158/1078-0432.22465520.v1