Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sarah G. Cook"'
Autor:
Carolyn Nicole Brown, Sarah G. Cook, Hillary F. Allen, Kevin C. Crosby, Tarjinder Singh, Steven J. Coultrap, K. Ulrich Bayer
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103184- (2021)
Summary: The Ca2+/Calmodulin-dependent protein kinase II (CaMKII) is a central regulator of synaptic plasticity and has been implicated in various neurological conditions, including schizophrenia. Here, we characterize six different CaMKIIα variants
Externí odkaz:
https://doaj.org/article/99bee0eeeb324359bf2282e2f6ae69cf
Autor:
Olivia R. Buonarati, Sarah G. Cook, Dayton J. Goodell, Nicholas E. Chalmers, Nicole L. Rumian, Jonathan E. Tullis, Susana Restrepo, Steven J. Coultrap, Nidia Quillinan, Paco S. Herson, K. Ulrich Bayer
Publikováno v:
Cell Reports, Vol 30, Iss 1, Pp 1-8.e4 (2020)
Summary: DAPK1 binding to GluN2B was prominently reported to mediate ischemic cell death in vivo. DAPK1 and CaMKII bind to the same GluN2B region, and their binding is mutually exclusive. Here, we show that mutating the binding region on GluN2B (L129
Externí odkaz:
https://doaj.org/article/0747266e16f346cea222f1e38a2efe82
Autor:
Brian G. Hiester, Ashley M. Bourke, Brooke L. Sinnen, Sarah G. Cook, Emily S. Gibson, Katharine R. Smith, Matthew J. Kennedy
Publikováno v:
Cell Reports, Vol 21, Iss 8, Pp 2134-2146 (2017)
The repertoire and abundance of proteins displayed on the surface of neuronal dendrites are tuned by regulated fusion of recycling endosomes (REs) with the dendritic plasma membrane. While this process is critical for neuronal function and plasticity
Externí odkaz:
https://doaj.org/article/c6d4bff6bfc64e148fb2bd02f5186df3
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 658-665.e4 (2019)
Summary: CaMKIIα is a central mediator of bidirectional synaptic plasticity, including long-term potentiation (LTP) and long-term depression (LTD). To study how CaMKIIα movement during plasticity is affected by soluble amyloid-β peptide oligomers
Externí odkaz:
https://doaj.org/article/9b95d3d605894d2dac4c4afc551adfa7
Autor:
Sheetal A. Raithatha, Jillian M. Hagel, Kaveh Matinkhoo, Lisa Yu, David Press, Sarah G. Cook, Govinda Sharma, Dhananjaya D., Glynnis Jensen, Jessica B. Lee, Charlie Cai, Jonathan Gallant, Jaideep S. Bains, Joseph E. Tucker, Peter J. Facchini
The psychedelic compound psilocybin has shown therapeutic benefit in the treatment of numerous psychiatric diseases. A recent randomized clinical trial conducted at Johns Hopkins Bayview Medical Center demonstrated the efficacy of psilocybin-assisted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f670e03ad5c8521c0f565abb4bfbbfa9
https://doi.org/10.1101/2023.05.16.540994
https://doi.org/10.1101/2023.05.16.540994
Publikováno v:
The Journal of biological chemistry. 298(9)
The Ca
The Ca2+/calmodulin-dependent protein kinase II (CaMKII) mediates both long-term potentiation and depression (LTP and LTD) of excitatory synapses, two opposing forms of synaptic plasticity induced by strong versus weak stimulation of NMDA-type glutam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e76cc1d19a953e12b8b5dc47d9f63632
https://doi.org/10.1101/2022.01.03.474759
https://doi.org/10.1101/2022.01.03.474759
Publikováno v:
Science Advances
Molecular signal computation within the CaMKII holoenzyme determines the direction of synaptic plasticity.
Higher brain functions are thought to require synaptic frequency decoding that can lead to long-term potentiation (LTP) or depression (LTD
Higher brain functions are thought to require synaptic frequency decoding that can lead to long-term potentiation (LTP) or depression (LTD
Autor:
Kevin C. Crosby, Carolyn N. Brown, K. Ulrich Bayer, Tarjinder Singh, Sarah G. Cook, Steven J. Coultrap, Hillary F. Allen
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103184-(2021)
iScience
iScience
Summary The Ca2+/Calmodulin-dependent protein kinase II (CaMKII) is a central regulator of synaptic plasticity and has been implicated in various neurological conditions, including schizophrenia. Here, we characterize six different CaMKIIα variants
Autor:
Matthew J. Kennedy, Brian G. Hiester, Emily S. Gibson, Katharine R. Smith, Brooke L. Sinnen, Ashley M. Bourke, Sarah G. Cook
Publikováno v:
Cell Reports, Vol 21, Iss 8, Pp 2134-2146 (2017)
The repertoire and abundance of proteins displayed on the surface of neuronal dendrites are tuned by regulated fusion of recycling endosomes (REs) with the dendritic plasma membrane. While this process is critical for neuronal function and plasticity