Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sarah G. Bradshaw"'
Autor:
Sarah G. Bradshaw, Patricia A. Fair, Se Hun Yun, Gregory D. Bossart, Margie M. Peden-Adams, Deborah E. Keil, Kurunthachalam Kannan, Meagan A M Mollenhauer, Erin Driscoll
Publikováno v:
Journal of Immunotoxicology. 8:17-29
In the first part of a series of studies to account for perfluorooctane sulfonate (PFOS)-induced sheep red blood cell (SRBC)-specific immunoglobulin M (IgM) antibody suppression in mice, a survey of clinical and immunotoxicological endpoints was exam
Publikováno v:
Clinical Immunology. 129:19-30
Transgenic overexpression of Fli-1 in normal mice leads to SLE-like disease and increased expression was reported in SLE-affected human and murine lymphocytes. Reducing Fli-1 expression in MRL/lpr mice decreased antibody production, proteinuria, rena
Autor:
Ashley J. Snider, Toshihiko Kawamori, Gary S. Gilkeson, Yusuf A. Hannun, Sarah G. Bradshaw, K. Alexa Orr, Lina M. Obeid
Publikováno v:
The FASEB Journal. 23:143-152
The bioactive lipid sphingosine-1-phosphate (S1P) is emerging as an important mediator of immune and inflammatory responses. S1P formation is catalyzed by sphingosine kinase (SK), of which the SK1 isoenzyme is activated by tumor necrosis alpha (TNF-
Autor:
Ivan Molano, Dennis K. Watson, Demetri D. Spyropoulos, Xian K. Zhang, Omar Moussa, Gary S. Gilkeson, Amanda C. LaRue, Sarah G. Bradshaw
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 181(3)
Fli-1 belongs to the Ets transcription factor family and is expressed primarily in hematopoietic cells, including most cells active in immunity. To assess the role of Fli-1 in lymphocyte development in vivo, we generated mice that express a truncated