Výsledky vyhledávání - "Sarah G, Crist"

Akademický článek

Estradiol regulation of nucleotidases in female reproductive tract epithelial cells and fibroblasts.

Autor: Zheng Shen, John V Fahey, Jack E Bodwell, Marta Rodriguez-Garcia, Richard M Rossoll, Sarah G Crist, Mickey V Patel, Charles R Wira

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e69854 (2013)

The use of topical and oral adenosine derivatives in HIV prevention that need to be maintained in tissues and cells at effective levels to prevent transmission prompted us to ask whether estradiol could influence the regulation of catabolic nucleotid

Externí odkaz: https://doaj.org/article/d68a385c19bd45718b5c61300c4b24ac

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Akademický článek

Effect of tenofovir on nucleotidases and cytokines in HIV-1 target cells.

Autor: Nabanita Biswas, Marta Rodriguez-Garcia, Sarah G Crist, Zheng Shen, Jack E Bodwell, John V Fahey, Charles R Wira

Publikováno v: PLoS ONE, Vol 8, Iss 10, p e78814 (2013)

Tenofovir (TFV) has been widely used for pre-exposure prophylaxis of HIV-1 infection with mixed results. While the use of TFV in uninfected individuals for prevention of HIV-1 acquisition is actively being investigated, the possible consequences of T

Externí odkaz: https://doaj.org/article/ab9e523dd40142d8a85d66cf29917621

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Akademický článek

Estradiol reduces susceptibility of CD4+ T cells and macrophages to HIV-infection.

Autor: Marta Rodriguez-Garcia, Nabanita Biswas, Mickey V Patel, Fiona D Barr, Sarah G Crist, Christina Ochsenbauer, John V Fahey, Charles R Wira

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e62069 (2013)

The magnitude of the HIV epidemic in women requires urgent efforts to find effective preventive methods. Even though sex hormones have been described to influence HIV infection in epidemiological studies and regulate different immune responses that m

Externí odkaz: https://doaj.org/article/b0205a82c121439f8baf73d42dbab8fb

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Modulation of Hepatocyte Growth Factor Secretion in Human Female Reproductive Tract Stromal Fibroblasts by Poly (I:C) and Estradiol

Autor: Richard M. Rossoll, Kimberly D. Coleman, Charles R. Wira, John V. Fahey, Jacqueline A. Wright, Sarah G. Crist, Mimi Ghosh

Publikováno v: American Journal of Reproductive Immunology. 67:44-53

Citation Coleman KD, Ghosh M, Crist SG, Wright JA, Rossoll RM, Wira CR, Fahey JV. Modulation of Hepatocyte Growth Factor secretion in human female reproductive tract stromal fibroblasts by poly (I:C) and estradiol. Am J Reprod Immunol 2012; 67: 44–

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cea9843d88a647d4e0c2e5cd99b54de1
https://doi.org/10.1111/j.1600-0897.2011.01063.x

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Control of murine gammaherpesvirus infection is independent of NK cells

Autor: Edward J. Usherwood, Sarah K. Meadows, Sarah C. Bellfy, Charles L. Sentman, Sarah G. Crist

Publikováno v: European Journal of Immunology. 35:2956-2961

Numerous studies have shown that NK cells are important in controlling the early stages of infection with alpha- or betaherpesviruses. In contrast, little is known about the impact of NK cells on gammaherpesvirus infections. We tested mice with defec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186a382e9a9a89c9d98d08b75ec810a6
https://doi.org/10.1002/eji.200526245

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T-Cell Responses to the M3 Immune Evasion Protein of Murid Gammaherpesvirus 68 Are Partially Protective and Induced with Lytic Antigen Kinetics

Autor: Ondine Silvia, James P. Stewart, Sarah G. Crist, Douglas C. Donovan, Edward J. Usherwood, Joshua J. Obar

Publikováno v: Journal of Virology. 78:10829-10832

DNA vaccination with theM3gene, encoding an immune evasion molecule expressed during both the acute lytic and persistent phases of murid gammaherpesvirus 68 infection, yielded a significantly lower titer of virus in the lung than controls. The protec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95dd6900d531715f267e6aca339f677
https://doi.org/10.1128/jvi.78.19.10829-10832.2004

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Different Functional Capacities of Latent and Lytic Antigen-Specific CD8 T Cells in Murine Gammaherpesvirus Infection

Autor: Sarah G. Crist, Edward J. Usherwood, David C. Gondek, Joshua J. Obar

Publikováno v: The Journal of Immunology. 172:1213-1219

Gammaherpesviruses can persist in the host in the face of an aggressive immune response. T cells recognize Ags expressed in both the productive and latent phases of the virus life cycle, however little is known about their relative roles in the long-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e082b991dbfd731bb3d4a95dd0248929
https://doi.org/10.4049/jimmunol.172.2.1213

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Effects of tenofovir on cytokines and nucleotidases in HIV-1 target cells and the mucosal tissue environment in the female reproductive tract

Autor: Charles R. Wira, Zheng Shen, Jack E. Bodwell, John V. Fahey, Nabanita Biswas, Marta Rodriguez-Garcia, Sarah G. Crist

Publikováno v: Antimicrobial agents and chemotherapy. 58(11)

Tenofovir (TFV) is a reverse transcriptase inhibitor used in microbicide preexposure prophylaxis trials to prevent HIV infection. Recognizing that changes in cytokine/chemokine secretion and nucleotidase biological activity can influence female repro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619114af116cf47ce8c556d422abde89
https://pubmed.ncbi.nlm.nih.gov/25136003

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