Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Sarah Farmer"'
Autor:
Veronica Pini, Virginie Mariot, Julie Dumonceaux, John Counsell, Helen C. O’Neill, Sarah Farmer, Francesco Conti, Francesco Muntoni
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Among the mutations arising in the DMD gene and causing Duchenne Muscular Dystrophy (DMD), 10–15% are multi-exon duplications. There are no current therapeutic approaches with the ability to excise large multi-exon duplications, leaving th
Externí odkaz:
https://doaj.org/article/f9737f98c68e4dc1b4e5032db9cf3319
Autor:
Jennifer K. Frediani, Joshua M. Levy, Anuradha Rao, Leda Bassit, Janet Figueroa, Miriam B. Vos, Anna Wood, Robert Jerris, Van Leung-Pineda, Mark D. Gonzalez, Beverly B. Rogers, Maud Mavigner, Raymond F. Schinazi, Nils Schoof, Jesse J. Waggoner, Russell R. Kempker, Paulina A. Rebolledo, Jared W. O’Neal, Cheryl Stone, Ann Chahroudi, Claudia R. Morris, Allie Suessmith, Julie Sullivan, Sarah Farmer, Amanda Foster, John D. Roback, Thanuja Ramachandra, CaDeidre Washington, Kristie Le, Maria C. Cordero, Annette Esper, Eric J. Nehl, Yun F. Wang, Erika A. Tyburski, Greg S. Martin, Wilbur A. Lam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract While there has been significant progress in the development of rapid COVID-19 diagnostics, as the pandemic unfolds, new challenges have emerged, including whether these technologies can reliably detect the more infectious variants of concer
Externí odkaz:
https://doaj.org/article/30016094be9f470888a58161d2407fd5
Autor:
Eric Nehl, Stacy Heilman, David Ku, David Gottfried, Sarah Farmer, Robert Mannino, Erika Tyburski, Julie Sullivan, Allison Suessmith, Leda Bassit, Janet Figueroa, Anna Wood, Traci Leong, Anuradha Rao, Beverly Rogers, Robert Jerris, Sunita Park, Mark Gonzalez, Jennifer Frediani, Claudia Morris, Joshua Levy, Nils Schoof, Maud Mavigner, John Roback, Kristen Herzegh, Natia Saakadze, Jess Ingersoll, Narayana Cheedarla, Andrew Neish, Bradley Hanberry, Christopher Porter, Annette Esper, Russell Kempker, Paulina Rebolledo, Pamela McGuinness, Frederick Balagadde, Rebecca Gore, Ainat Koren, Nira Pollock, Eugene Rogers, Karl Simin, Nathaniel Hafer, Mary Ann Picard, Chiara Ghezzi, David McManus, Bryan Buchholz, Christina Rostad, Viviana Claveria, Thanuja Ramachandra, Yun F. Wang, CaDeidre Washington, Cheryl Stone, Mark Griffiths, Ray Schinazi, Ann Chahroudi, Miriam Vos, Oliver Brand, Greg Martin, Wilbur Lam
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 2, Pp 142-151 (2021)
Faced with the COVID-19 pandemic, the US system for developing and testing technologies was challenged in unparalleled ways. This article describes the multi-institutional, transdisciplinary team of the “RADxSM Tech Test Verification Core” and it
Externí odkaz:
https://doaj.org/article/97dd1f4fe14142b5900fb67b6edd4cb6
Autor:
Catia Caetano, Oliver Limbo, Sarah Farmer, Steffi Klier, Claire Dovey, Paul Russell, Robertus Antonius Maria de Bruin
Publikováno v:
Cell Reports, Vol 9, Iss 6, Pp 2279-2289 (2014)
Expression of a G1/S regulon of genes that are required for DNA replication is a ubiquitous mechanism for controlling cell proliferation; moreover, the pathological deregulated expression of E2F-regulated G1/S genes is found in every type of cancer.
Externí odkaz:
https://doaj.org/article/2e06dcf3965e4590949425e03f73f6db
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61059 (2013)
G1/S transcriptional regulation in the budding yeast Saccharomyces cerevisiae depends on three main transcriptional components, Swi4, Swi6 and Mbp1. These proteins constitute two transcription factor complexes that regulate over 300 G1/S transcripts,
Externí odkaz:
https://doaj.org/article/904b6e83827246618078d823bf5c4c10
Autor:
Bilge Argunhan, Sarah Farmer, Wing-Kit Leung, Yaroslav Terentyev, Neil Humphryes, Tomomi Tsubouchi, Hiroshi Toyoizumi, Hideo Tsubouchi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65875 (2013)
Meiotic recombination plays an essential role in the proper segregation of chromosomes at meiosis I in many sexually reproducing organisms. Meiotic recombination is initiated by the scheduled formation of genome-wide DNA double-strand breaks (DSBs).
Externí odkaz:
https://doaj.org/article/080c5430a0214f34915880afabff701b
Autor:
Sarah Farmer, Eun-Jin Erica Hong, Wing-Kit Leung, Bilge Argunhan, Yaroslav Terentyev, Neil Humphryes, Hiroshi Toyoizumi, Hideo Tsubouchi
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39724 (2012)
Budding yeast Pch2 protein is a widely conserved meiosis-specific protein whose role is implicated in the control of formation and displacement of meiotic crossover events. In contrast to previous studies where the function of Pch2 was implicated in
Externí odkaz:
https://doaj.org/article/ac797ae5b34447bd944501e558b75e2f
Autor:
Sarah Farmer, Eun-Jin Erica Hong, Wing-Kit Leung, Bilge Argunhan, Yaroslav Terentyev, Neil Humphryes, Hiroshi Toyoizumi, Hideo Tsubouchi
Publikováno v:
PLoS ONE, Vol 7, Iss 10 (2012)
Externí odkaz:
https://doaj.org/article/0ec5f91fa42e4421b6e40c3d9c1a720d
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20948 (2011)
Meiosis, a specialized cell division with a single cycle of DNA replication round and two consecutive rounds of nuclear segregation, allows for the exchange of genetic material between parental chromosomes and the formation of haploid gametes. The st
Externí odkaz:
https://doaj.org/article/3f38cecdbae24c8bb100d25c1a9ebfc6
Publikováno v:
International Journal of E-Planning Research. 11:1-15
In the era of COVID-19 planners, and more broadly, city administrators and policy makers, have learned to cope with the accelerated pace of change, the broad band of uncertainty, and the need for rapid decision-making strategies. This, in the context