Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sarah F. Stuart"'
Autor:
Sarah F. Stuart, Peter Curpen, Adele J. Gomes, Michelle C. Lan, Shuai Nie, Nicholas A. Williamson, George Kannourakis, Andrew P. Morokoff, Adrian A. Achuthan, Rodney B. Luwor
Publikováno v:
Brain Sciences, Vol 14, Iss 1, p 89 (2024)
Glioblastoma is highly proliferative and invasive. However, the regulatory cytokine networks that promote glioblastoma cell proliferation and invasion into other areas of the brain are not fully defined. In the present study, we define a critical rol
Externí odkaz:
https://doaj.org/article/67b463ca5fd74a849d24bbbf4752968b
Autor:
Sarah F. Stuart, Ayenachew Bezawork-Geleta, Zammam Areeb, Juliana Gomez, Vanessa Tsui, Ahmad Zulkifli, Lucia Paradiso, Jordan Jones, Hong P. T. Nguyen, Tracy L. Putoczki, Paul V. Licciardi, George Kannourakis, Andrew P. Morokoff, Adrian A. Achuthan, Rodney B. Luwor
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3356 (2023)
Glioblastoma cells adapt to changes in glucose availability through metabolic plasticity allowing for cell survival and continued progression in low-glucose concentrations. However, the regulatory cytokine networks that govern the ability to survive
Externí odkaz:
https://doaj.org/article/746896258fcb47fa865cf5f0a4cfda65
Autor:
Ahmad Zulkifli, Fiona H. Tan, Zammam Areeb, Sarah F. Stuart, Juliana Gomez, Lucia Paradiso, Rodney B. Luwor
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7114 (2021)
Cetuximab is a common treatment option for patients with wild-type K-Ras colorectal carcinoma. However, patients often display intrinsic resistance or acquire resistance to cetuximab following treatment. Here we generate two human CRC cells with acqu
Externí odkaz:
https://doaj.org/article/3674d11604b24b92b1be3d47a5ec2eaa
Autor:
Juliana Gomez, Zammam Areeb, Sarah F. Stuart, Hong P. T. Nguyen, Lucia Paradiso, Ahmad Zulkifli, Sonakshi Madan, Vijay Rajagopal, Magdalene K. Montgomery, Hui K. Gan, Andrew M. Scott, Jordan Jones, Andrew H. Kaye, Andrew P. Morokoff, Rodney B. Luwor
Publikováno v:
Cancers, Vol 13, Iss 6, p 1198 (2021)
Reticulocalbin 1 (RCN1) is an endoplasmic reticulum (ER)-residing protein, involved in promoting cell survival during pathophysiological conditions that lead to ER stress. However, the key upstream receptor tyrosine kinase that regulates RCN1 express
Externí odkaz:
https://doaj.org/article/4e7ab66647e94fccb77f168917810ebd
Autor:
Juliana Gomez, Ahmad Zulkifli, Zammam Areeb, Fiona H Tan, Rodney B. Luwor, Lucia Paradiso, Sarah F. Stuart
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7114, p 7114 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences
Volume 22
Issue 13
Cetuximab is a common treatment option for patients with wild-type K-Ras colorectal carcinoma. However, patients often display intrinsic resistance or acquire resistance to cetuximab following treatment. Here we generate two human CRC cells with acqu
Autor:
Hong P. T. Nguyen, Ahmad Zulkifli, Zammam Areeb, Sarah F. Stuart, Jordan Jones, Lucia Paradiso, Andrew H. Kaye, Vijay Rajagopal, Sonakshi Madan, Hui K Gan, Magdalene K. Montgomery, Juliana Gomez, Andrew P. Morokoff, Andrew M. Scott, Rodney B. Luwor
Publikováno v:
Cancers
Volume 13
Issue 6
Cancers, Vol 13, Iss 1198, p 1198 (2021)
Volume 13
Issue 6
Cancers, Vol 13, Iss 1198, p 1198 (2021)
Simple Summary A key molecule, EGFRvIII has been shown to provide several growth advantages for brain tumors. However, we have found a new mechanism in which the EGFRvIII provides increased survival to brain cancer cells when under sub-optimal condit
Autor:
Sarah F. Stuart, Jordan Jones, Alice J. West, Hong P. T. Nguyen, Andrew H. Kaye, Ahmad Zulkifli, Rodney B. Luwor, Zammam Areeb, Andrew P. Morokoff, Lucia Paradiso, Juliana Gomez
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Despite aggressive treatment with temozolomide and radiotherapy and extensive research into alternative therapies there has been little improvement in Glioblastoma patient survival. Median survival time remains between 12 and 15 months mainly due to
Actin requires the chaperonin containing TCP1 (CCT), a hexadecameric ATPase essential for cell viability in eukaryotes, to fold to its native state. Following binding of unfolded actin to CCT, the cavity of the chaperone closes and actin is folded an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eea6c390a0e23b4aaa426b123dc9479
https://europepmc.org/articles/PMC3012972/
https://europepmc.org/articles/PMC3012972/