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pro vyhledávání: '"Sarah F McComish"'
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Parkinson’s disease (PD) is the second most common neurodegenerative disease and affects approximately 2–3% of the population over the age of 65. PD is characterised by the loss of dopaminergic neurons from the substantia nigra, leading to debili
Externí odkaz:
https://doaj.org/article/7bdb586279e94252903ed3bf776f82f7
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Parkinson's disease (PD), the second most common neurodegenerative disease, is characterised by the motor symptoms of bradykinesia, rigidity and resting tremor and non-motor symptoms of sleep disturbances, constipation, and depression. Pathological h
Externí odkaz:
https://doaj.org/article/40feebbf21934cd7962697846a45c5bc
Autor:
Lucy A Crompton, Sarah F McComish, Tom G J Steward, Daniel J Whitcomb, Jon D Lane, Maeve A Caldwell
Publikováno v:
Brain Communications. 5
This scientific commentary refers to ‘Human stem cell-derived astrocytes exhibit region-specific heterogeneity in their secretory profiles’, by Clarke et al. (https://doi.org/10.1093/brain/awaa258) in Brain.
Autor:
Jack Maughan, Pedro J. Gouveia, Javier Gutierrez Gonzalez, Liam M. Leahy, Ian Woods, Cian O'Connor, Tara McGuire, James R. Garcia, Donagh G. O’ Shea, Sarah F. McComish, Oran D. Kennedy, Maeve A. Caldwell, Adrian Dervan, Jonathan N. Coleman, Fergal J. O'Brien
Publikováno v:
Applied Materials Today. 29:101629
Autor:
Maeve A. Caldwell, Sarah F. McComish
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 373(1750)
Effective and efficient generation of human neural stem cells and subsequently functional neural populations from pluripotent stem cells has facilitated advancements in the study of human development and disease modelling. This review will discuss th