Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sarah Elschenbroich"'
Autor:
Axel Ducret, Ian James, Sabine Wilson, Martina Feilke, Andreas Tebbe, Nikolaj Dybowski, Sarah Elschenbroich, Martin Klammer, Adele Blackler, Wei-Li Liao, Yuan Tian, Thomas Friess, Birgit Bossenmaier, Gabriele Dietmann, Christoph Schaab, Todd Hembrough, Maurizio Ceppi
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213892 (2019)
Human protein biomarker discovery relies heavily on pre-clinical models, in particular established cell lines and patient-derived xenografts, but confirmation studies in primary tissue are essential to demonstrate clinical relevance. We describe in t
Externí odkaz:
https://doaj.org/article/7a868f37ec724ad9b8d88559716f55cb
Autor:
Sebastian K Wandinger, Idoya Lahortiga, Kris Jacobs, Martin Klammer, Nicole Jordan, Sarah Elschenbroich, Marc Parade, Edgar Jacoby, Joannes T M Linders, Dirk Brehmer, Jan Cools, Henrik Daub
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146100 (2016)
The four members of the epidermal growth factor receptor (EGFR/ERBB) family form homo- and heterodimers which mediate ligand-specific regulation of many key cellular processes in normal and cancer tissues. While signaling through the EGFR has been ex
Externí odkaz:
https://doaj.org/article/26db43b838524974a1a9f9e2ce99ecbe
Autor:
Taneli Heikkinen, J. Nikolaj Dybowski, Larry Park, Fernando E. Padovan-Neto, Amyaouch Bradaia, John F. Harms, Vahri Beaumont, Miklós Tóth, Esther Steidl, Sheng Zhong, Margaret M. Zaleska, Kristian Wadel, Ladislav Mrzljak, Kimmo Lehtimäki, Karen M. Ward, Shreaya Chakroborty, Sarah Elschenbroich, Christer Halldin, Andrea Varrone, Christopher J. Schmidt, Afshin Ghavami, WenJin Xu, Ignacio Munoz-Sanjuan, Mei Kwan, Jose Beltran, Bruno Buisson, Christoph Schaab, Jim Rosinski, Daniel J. Lavery, Anthony R. West, Jenny Häggkvist, Melanie Gleyzes, Hai Lin
Publikováno v:
Neuron. 92:1220-1237
Summary Huntington's disease (HD) symptoms are driven to a large extent by dysfunction of the basal ganglia circuitry. HD patients exhibit reduced striatal phoshodiesterase 10 (PDE10) levels. Using HD mouse models that exhibit reduced PDE10, we demon
Autor:
Anthony O. Gramolini, Sarah Elschenbroich, Thomas Kislinger, Patricia Shaw, Igor Jurisica, Paul C. Boutros, Vladimir Ignatchenko, Steve E. Kalloger, Blaise A. Clarke
Publikováno v:
Journal of Proteome Research. 10:2286-2299
Epithelial ovarian cancer (EOC) is the most common gynecological cancer and the ninth most common cancer overall. Major problems associated with EOC include poorly characterized disease progression, disease heterogeneity, lack of early detection mark
Autor:
Sarah Elschenbroich, Thomas Kislinger
Publikováno v:
Mol. BioSyst.. 7:292-303
Mass Spectrometry-based proteomics is now considered a relatively established strategy for protein analysis, ranging from global expression profiling to the identification of protein complexes and specific post-translational modifications. Recently,
Autor:
Thomas Kislinger, Yunee Kim, Gaurav Basu, Breanne N. Gjurich, Julius O. Nyalwidhe, O. John Semmes, Vladimir Ignatchenko, Orlay Lopez-Perez, Raymond S. Lance, Christopher E. Wilkins, Sarah Elschenbroich, Jeffrey A. Medin, Alex Ignatchenko, Richard R. Drake
Publikováno v:
Journal of Proteome Research. 9:2109-2116
It is expected that clinically obtainable fluids that are proximal to organs contain a repertoire of secreted proteins and shed cells reflective of the physiological state of that tissue and thus represent potential sources for biomarker discovery, i
Publikováno v:
Expert Review of Proteomics. 7:141-154
Defining the cell surface proteome has profound importance for understanding cell differentiation and cell–cell interactions, as well as numerous pathogenic abnormalities. Owing to their hydrophobic nature, plasma membrane proteins that reside on t
Autor:
Anthony O. Gramolini, Thomas Kislinger, Vladimir Ignatchenko, Parveen Sharma, Gerold Schmitt-Ulms, Sarah Elschenbroich
Publikováno v:
Journal of Proteome Research. 8:4860-4869
High resolution peptide separation is pivotal for successful shot-gun proteomics. The need for capable techniques propels invention and improvement of ever more sophisticated approaches. Recently, Agilent Technologies has introduced the OFFGEL fracti
Autor:
Sarah Elschenbroich, Jan Cools, Sebastian K. Wandinger, Kris Jacobs, Martin Klammer, Idoya Lahortiga, Edgar Jacoby, Dirk Brehmer, Henrik Daub, Joannes T. M. Linders, Marc Parade, Nicole Jordan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 1, p e0146100 (2016)
PLoS ONE, Vol 11, Iss 1, p e0146100 (2016)
The four members of the epidermal growth factor receptor (EGFR/ERBB) family form homo- and heterodimers which mediate ligand-specific regulation of many key cellular processes in normal and cancer tissues. While signaling through the EGFR has been ex
Autor:
Thomas Kislinger, Yunee Kim, Anthony O. Gramolini, Lusia Sepiashvili, Parveen Sharma, Sarah Elschenbroich
Publikováno v:
Methods in Molecular Biology ISBN: 9781617791383
Chaney and Jacobson first introduced the colloidal silica-bead protocol for the coating of cellular plasma membranes in the early 1980s. Since then, this method has been successfully incorporated into a wide range of in vitro and in vivo applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524901cb102d346705874955a3f7454d
https://doi.org/10.1007/978-1-61779-139-0_16
https://doi.org/10.1007/978-1-61779-139-0_16