Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sarah El Chamy Maluf"'
Autor:
Sarah El Chamy Maluf, Marcelo Yudi Icimoto, Pollyana Maria Saud Melo, Alexandre Budu, Rita Coimbra, Marcos Leoni Gazarini, Adriana Karaoglanovic Carmona
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background The intra-erythrocytic development of the malaria parasite Plasmodium falciparum depends on the uptake of a number of essential nutrients from the host cell and blood plasma. It is widely recognized that the parasite imports low m
Externí odkaz:
https://doaj.org/article/87efd33c13dc411baf4741971195b93b
Autor:
Camila S. Barbosa, Anees Ahmad, Sarah El Chamy Maluf, Igor M. R. Moura, Guilherme E. Souza, Giovanna A. H. Guerra, Roberto R. Moraes Barros, Marcos L. Gazarini, Anna C. C. Aguiar, Antonio C. B. Burtoloso, Rafael V. C. Guido
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 814 (2022)
Malaria is a parasitic disease caused by protozoan parasites from the genus Plasmodium. Plasmodium falciparum is the most prevalent species worldwide and the causative agent of severe malaria. The spread of resistance to the currently available antim
Externí odkaz:
https://doaj.org/article/5cb56a9f4ef64e86a78520d3a1c23120
Autor:
Carolina C. Hoff, Mauro F. Azevedo, Adriana B. Thurler, Sarah El Chamy Maluf, Pollyana M. S. Melo, Maday Alonso del Rivero, Jorge González-Bacerio, Adriana K. Carmona, Alexandre Budu, Marcos L. Gazarini
Publikováno v:
Pathogens, Vol 10, Iss 11, p 1452 (2021)
Plasmodium falciparum, the most virulent of the human malaria parasite, is responsible for high mortality rates worldwide. We studied the M1 alanyl-aminopeptidase of this protozoan (PfA-M1), which is involved in the final stages of hemoglobin cleavag
Externí odkaz:
https://doaj.org/article/a0d20a6310e044c2a2d8837dadf331db
Autor:
Alexandre Budu, Pollyana S. Melo, Marcelo Y. Icimoto, Sarah El Chamy Maluf, Marcos L. Gazarini, Rita de Cassia Sinigaglia Galli Coimbra, Adriana K. Carmona
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-10 (2020)
Malaria Journal
Malaria Journal
Background The intra-erythrocytic development of the malaria parasite Plasmodium falciparum depends on the uptake of a number of essential nutrients from the host cell and blood plasma. It is widely recognized that the parasite imports low molecular
Autor:
Carolina C, Hoff, Mauro F, Azevedo, Adriana B, Thurler, Sarah El Chamy, Maluf, Pollyana M S, Melo, Maday Alonso, Del Rivero, Jorge, González-Bacerio, Adriana K, Carmona, Alexandre, Budu, Marcos L, Gazarini
Publikováno v:
Pathogens
Plasmodium falciparum, the most virulent of the human malaria parasite, is responsible for high mortality rates worldwide. We studied the M1 alanyl-aminopeptidase of this protozoan (PfA-M1), which is involved in the final stages of hemoglobin cleavag
Autor:
Andrea Soares-Costa, Thaysa Paschoalin, Alexandre Budu, Mauro F Azevedo, Sarah El Chamy Maluf, Pollyana M.S. Melo, Piero Bagnaresi, Marcos L. Gazarini, Flávio Henrique-Silva, Adriana K. Carmona
Publikováno v:
Parasitology International. 67:233-236
Malaria is a disease caused by Plasmodium parasites that affects hundreds of millions of people. Plasmodium proteases are involved in invasion, erythrocyte egress and degradation of host proteins. Falcipains are well-studied cysteine peptidases locat
Autor:
Pollyana M.S. Melo, Marcos L. Gazarini, Adriana B Thurler, Mauro F Azevedo, Jorge González-Bacerio, Sarah El Chamy Maluf, Adriana K. Carmona, Alexandre Budu, Carolina Caldas Hoff, Maday Alonso del Rivero
Publikováno v:
Pathogens
Volume 10
Issue 11
Pathogens, Vol 10, Iss 1452, p 1452 (2021)
Volume 10
Issue 11
Pathogens, Vol 10, Iss 1452, p 1452 (2021)
Plasmodium falciparum, the most virulent of the human malaria parasite, is responsible for high mortality rates worldwide. We studied the M1 alanyl-aminopeptidase of this protozoan (PfA-M1), which is involved in the final stages of hemoglobin cleavag
Autor:
Fellipe Bronze dos Santos, Taíse Fernanda da Silva Ferrara, Marcos L. Gazarini, Piero Bagnaresi, Alexandre Budu, Mauro F Azevedo, Marcelo Marcondes Ferreira Machado, Adriana K. Carmona, Mayrim M. Gomes Smaul, Sarah El Chamy Maluf, Georgina N. Montagna
Publikováno v:
Biochemical and biophysical research communications. 503(2)
Calcium signaling has an essential role in fundamental processes of Plasmodium life cycle, including migration, cell invasion and parasite development. Two important players in calcium homeostasis, the Histidine Triad (HIT) protein that is implicated
Autor:
Marcos L. Gazarini, Fernando de Pilla Varotti, Pollyana M.S. Melo, Sarah El Chamy Maluf, Rodrigo L. O. R. Cunha, Adriana K. Carmona
Publikováno v:
Parasitology International. 65:20-22
Hypervalent organotellurium compounds (organotelluranes) have shown several promising applications, including their use as potent and selective cysteine protease inhibitors and antiprotozoal agents. Here, we report the antimalarial activities of thre
Autor:
Juliana C. Ferreira, Maday Alonso del Rivero, Ernesto Moreno, Yanira Méndez, Alexandre Budu, Isabelle Florent, Adriana K. Carmona, Daniel G. Rivera, Jorge González-Bacerio, Isel Pascual, Sarah El Chamy Maluf, Pollyana M.S. Melo, Marcos L. Gazarini
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2017, 25 (17), pp.4628-4636. ⟨10.1016/j.bmc.2017.06.047⟩
Bioorganic and Medicinal Chemistry, 2017, 25 (17), pp.4628-4636. ⟨10.1016/j.bmc.2017.06.047⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2017, 25 (17), pp.4628-4636. ⟨10.1016/j.bmc.2017.06.047⟩
Bioorganic and Medicinal Chemistry, 2017, 25 (17), pp.4628-4636. ⟨10.1016/j.bmc.2017.06.047⟩
Malaria is a global human parasitic disease mainly caused by the protozoon Plasmodium falciparum. Increased parasite resistance to current drugs determines the relevance of finding new treatments against new targets. A novel target is the M1 alanyl-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8cf2c310fce75bf76903a0c5f1d778
https://hal.archives-ouvertes.fr/hal-02134397
https://hal.archives-ouvertes.fr/hal-02134397