Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sarah El Chamy, Maluf"'
Autor:
Sarah El Chamy Maluf, Marcelo Yudi Icimoto, Pollyana Maria Saud Melo, Alexandre Budu, Rita Coimbra, Marcos Leoni Gazarini, Adriana Karaoglanovic Carmona
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background The intra-erythrocytic development of the malaria parasite Plasmodium falciparum depends on the uptake of a number of essential nutrients from the host cell and blood plasma. It is widely recognized that the parasite imports low m
Externí odkaz:
https://doaj.org/article/87efd33c13dc411baf4741971195b93b
Autor:
Camila S. Barbosa, Anees Ahmad, Sarah El Chamy Maluf, Igor M. R. Moura, Guilherme E. Souza, Giovanna A. H. Guerra, Roberto R. Moraes Barros, Marcos L. Gazarini, Anna C. C. Aguiar, Antonio C. B. Burtoloso, Rafael V. C. Guido
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 814 (2022)
Malaria is a parasitic disease caused by protozoan parasites from the genus Plasmodium. Plasmodium falciparum is the most prevalent species worldwide and the causative agent of severe malaria. The spread of resistance to the currently available antim
Externí odkaz:
https://doaj.org/article/5cb56a9f4ef64e86a78520d3a1c23120
Autor:
Carolina C. Hoff, Mauro F. Azevedo, Adriana B. Thurler, Sarah El Chamy Maluf, Pollyana M. S. Melo, Maday Alonso del Rivero, Jorge González-Bacerio, Adriana K. Carmona, Alexandre Budu, Marcos L. Gazarini
Publikováno v:
Pathogens, Vol 10, Iss 11, p 1452 (2021)
Plasmodium falciparum, the most virulent of the human malaria parasite, is responsible for high mortality rates worldwide. We studied the M1 alanyl-aminopeptidase of this protozoan (PfA-M1), which is involved in the final stages of hemoglobin cleavag
Externí odkaz:
https://doaj.org/article/a0d20a6310e044c2a2d8837dadf331db
Autor:
Alexandre Budu, Pollyana S. Melo, Marcelo Y. Icimoto, Sarah El Chamy Maluf, Marcos L. Gazarini, Rita de Cassia Sinigaglia Galli Coimbra, Adriana K. Carmona
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-10 (2020)
Malaria Journal
Malaria Journal
Background The intra-erythrocytic development of the malaria parasite Plasmodium falciparum depends on the uptake of a number of essential nutrients from the host cell and blood plasma. It is widely recognized that the parasite imports low molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f3a41c48bb0fb7b74cc4fed7be7f3a
http://link.springer.com/article/10.1186/s12936-020-03377-4
http://link.springer.com/article/10.1186/s12936-020-03377-4
Autor:
Carolina C, Hoff, Mauro F, Azevedo, Adriana B, Thurler, Sarah El Chamy, Maluf, Pollyana M S, Melo, Maday Alonso, Del Rivero, Jorge, González-Bacerio, Adriana K, Carmona, Alexandre, Budu, Marcos L, Gazarini
Publikováno v:
Pathogens
Plasmodium falciparum, the most virulent of the human malaria parasite, is responsible for high mortality rates worldwide. We studied the M1 alanyl-aminopeptidase of this protozoan (PfA-M1), which is involved in the final stages of hemoglobin cleavag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5776111638b225106e2acc873201cc63
https://pubmed.ncbi.nlm.nih.gov/34832608
https://pubmed.ncbi.nlm.nih.gov/34832608
Autor:
Andrea Soares-Costa, Thaysa Paschoalin, Alexandre Budu, Mauro F Azevedo, Sarah El Chamy Maluf, Pollyana M.S. Melo, Piero Bagnaresi, Marcos L. Gazarini, Flávio Henrique-Silva, Adriana K. Carmona
Publikováno v:
Parasitology International. 67:233-236
Malaria is a disease caused by Plasmodium parasites that affects hundreds of millions of people. Plasmodium proteases are involved in invasion, erythrocyte egress and degradation of host proteins. Falcipains are well-studied cysteine peptidases locat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7ccfece094de8ffc60480d03e71e888
https://doi.org/10.1016/j.parint.2017.12.005
https://doi.org/10.1016/j.parint.2017.12.005
Autor:
Pollyana M.S. Melo, Marcos L. Gazarini, Adriana B Thurler, Mauro F Azevedo, Jorge González-Bacerio, Sarah El Chamy Maluf, Adriana K. Carmona, Alexandre Budu, Carolina Caldas Hoff, Maday Alonso del Rivero
Publikováno v:
Pathogens
Volume 10
Issue 11
Pathogens, Vol 10, Iss 1452, p 1452 (2021)
Volume 10
Issue 11
Pathogens, Vol 10, Iss 1452, p 1452 (2021)
Plasmodium falciparum, the most virulent of the human malaria parasite, is responsible for high mortality rates worldwide. We studied the M1 alanyl-aminopeptidase of this protozoan (PfA-M1), which is involved in the final stages of hemoglobin cleavag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33aadb9879f3ec998c8b3dc3770050d5
https://doi.org/10.3390/pathogens10111452
https://doi.org/10.3390/pathogens10111452
Autor:
Fellipe Bronze dos Santos, Taíse Fernanda da Silva Ferrara, Marcos L. Gazarini, Piero Bagnaresi, Alexandre Budu, Mauro F Azevedo, Marcelo Marcondes Ferreira Machado, Adriana K. Carmona, Mayrim M. Gomes Smaul, Sarah El Chamy Maluf, Georgina N. Montagna
Publikováno v:
Biochemical and biophysical research communications. 503(2)
Calcium signaling has an essential role in fundamental processes of Plasmodium life cycle, including migration, cell invasion and parasite development. Two important players in calcium homeostasis, the Histidine Triad (HIT) protein that is implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1de3029709ad0de055f32fae84811f2
https://pubmed.ncbi.nlm.nih.gov/29913151
https://pubmed.ncbi.nlm.nih.gov/29913151
Autor:
Marcos L. Gazarini, Fernando de Pilla Varotti, Pollyana M.S. Melo, Sarah El Chamy Maluf, Rodrigo L. O. R. Cunha, Adriana K. Carmona
Publikováno v:
Parasitology International. 65:20-22
Hypervalent organotellurium compounds (organotelluranes) have shown several promising applications, including their use as potent and selective cysteine protease inhibitors and antiprotozoal agents. Here, we report the antimalarial activities of thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a27ed96bc3f6e03207b81190aef0aa3
https://doi.org/10.1016/j.parint.2015.09.006
https://doi.org/10.1016/j.parint.2015.09.006
Autor:
Juliana C. Ferreira, Maday Alonso del Rivero, Ernesto Moreno, Yanira Méndez, Alexandre Budu, Isabelle Florent, Adriana K. Carmona, Daniel G. Rivera, Jorge González-Bacerio, Isel Pascual, Sarah El Chamy Maluf, Pollyana M.S. Melo, Marcos L. Gazarini
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2017, 25 (17), pp.4628-4636. ⟨10.1016/j.bmc.2017.06.047⟩
Bioorganic and Medicinal Chemistry, 2017, 25 (17), pp.4628-4636. ⟨10.1016/j.bmc.2017.06.047⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2017, 25 (17), pp.4628-4636. ⟨10.1016/j.bmc.2017.06.047⟩
Bioorganic and Medicinal Chemistry, 2017, 25 (17), pp.4628-4636. ⟨10.1016/j.bmc.2017.06.047⟩
Malaria is a global human parasitic disease mainly caused by the protozoon Plasmodium falciparum. Increased parasite resistance to current drugs determines the relevance of finding new treatments against new targets. A novel target is the M1 alanyl-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8cf2c310fce75bf76903a0c5f1d778
https://hal.archives-ouvertes.fr/hal-02134397
https://hal.archives-ouvertes.fr/hal-02134397
