Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Sarah E. Rice"'
Autor:
Dana H. Kotler, Mary Alexis Iaccarino, Ross Zafonte, Saurabha Bhatnagar, Greg Robidoux, Sarah E. Rice
Publikováno v:
J Athl Train
ContextCycling crashes are common among recreational and competitive riders and may result in head and bodily trauma. Information is limited regarding the signs and symptoms of head injury (HI) after cycling crashes, medical treatment, and recovery.O
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66669 (2013)
Kinesin-like calmodulin binding protein (KCBP), a Kinesin-14 family motor protein, is involved in the structural organization of microtubules during mitosis and trichome morphogenesis in plants. The molecular mechanism of microtubule bundling by KCBP
Externí odkaz:
https://doaj.org/article/9593d6730af243a18a368c0eac3bc421
Publikováno v:
Journal of Biological Chemistry. 292:16539-16553
Ring-between-ring (RBR) E3 ligases have been implicated in autoimmune disorders and neurodegenerative diseases. The functions of many RBR E3s are poorly defined, and their regulation is complex, involving post-translational modifications and alloster
Autor:
Patricia Wadsworth, Barbara J. Mann, Kathleen G. Bickel, Sarah E. Rice, Joshua S. Waitzman, Taylor A. Poor
Publikováno v:
Cytoskeleton. 74:317-330
Spindle formation in mammalian cells requires precise spatial and temporal regulation of the kinesin-5, Eg5, which generates outward force to establish spindle bipolarity. Our results demonstrate that Eg5 is phosphorylated in cultured cells by Src fa
Autor:
Kyle P. Smith, Eric C. Landahl, Douglas M. Freymann, Pamela J. Focia, Sarah E. Rice, Julian L. Klosowiak, Srinivas Chakravarthy
Publikováno v:
J Struct Biol
Dysfunction in mitochondrial dynamics is believed to contribute to a host of neurological disorders and has recently been implicated in cancer metastasis. The outer mitochondrial membrane adapter protein Miro functions in the regulation of mitochondr
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 83:25-36
While it is currently estimated that 40–50% of eukaryotic proteins are phosphorylated, little is known about the frequency and local effects of phosphorylation near pharmaceutical inhibitor binding sites. In this study, we investigated how frequent
Autor:
Sarah E. Rice
Publikováno v:
Journal of Molecular Biology. 426:2993-2996
Autor:
Sarah E. Rice, Joshua S. Waitzman
Publikováno v:
Biology of the Cell. 106:1-12
Mitotic cell division is the most fundamental task of all living cells. Cells have intricate and tightly regulated machinery to ensure that mitosis occurs with appropriate frequency and high fidelity. A core element of this machinery is the kinesin-5
Autor:
Srinivas Chakravarthy, Pamela J. Focia, Sarah E. Rice, Eric C. Landahl, Douglas M. Freymann, Julian L. Klosowiak
Publikováno v:
EMBO reports. 14:968-974
Miro is a highly conserved calcium-binding GTPase at the regulatory nexus of mitochondrial transport and autophagy. Here we present crystal structures comprising the tandem EF hand and carboxy terminal GTPase (cGTPase) domains of Drosophila Miro. The
Autor:
Michael E. French, Sungjin Park, Sarah E. Rice, Julian L. Klosowiak, Kyle P. Smith, Douglas M. Freymann, Pamela J. Focia
Publikováno v:
Scientific Reports
Hereditary Parkinson’s disease is commonly caused by mutations in the protein kinase PINK1 or the E3 ubiquitin ligase Parkin, which function together to eliminate damaged mitochondria. PINK1 phosphorylates both Parkin and ubiquitin to stimulate ubi