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pro vyhledávání: '"Sarah E. Nikolai"'
Publikováno v:
Molecular Endocrinology. 19:1765-1778
Despite the important roles of both prolactin (PRL) and 17beta-estradiol (E2) in normal mammary development as well as in breast cancer, and coexpression of the estrogen receptor (ER) and PRL receptor in many mammary tumors, the interactions between
Publikováno v:
Oncogene. 26(43)
The essential role of prolactin (PRL) in normal mammary gland growth and differentiation has implicated this hormone in the development and progression of breast cancer. Although Stat5 is the best-characterized mediator of PRL signals, PRL also activ
Autor:
Kristin M. Wentworth, Donald W. Kundel, Sarah E. Nikolai, Teresa A. Rose-Hellekant, Eric P. Sandgren
Publikováno v:
The American journal of pathology. 169(5)
Identification of biomarkers that indicate an increased risk of breast cancer or that can be used as surrogates for evaluating treatment efficacy is paramount to successful disease prevention and intervention. An ideal biomarker would be identifiable