Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sarah E. Mondello"'
Publikováno v:
Frontiers in Neuroscience, Vol 8 (2014)
Neuroprosthetic approaches have tremendous potential for the treatment of injuries to the brain and spinal cord by inducing appropriate neural activity in otherwise disordered circuits. Substantial work has demonstrated that stimulation applied to bo
Externí odkaz:
https://doaj.org/article/05cbf6dbc49e466a85e0016d4743a7da
Publikováno v:
Experimental Neurology. 357:114178
Spinal cord injuries lead to permanent physical impairment despite most often being anatomically incomplete disruptions of the spinal cord. Remaining connections between the brain and spinal cord create the potential for inducing neural plasticity to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c161c1f7fb0288f80c7b0dc0dfd5e2
https://doi.org/10.1016/j.expneurol.2022.114178
https://doi.org/10.1016/j.expneurol.2022.114178
Autor:
Soshi Samejima, Aiva M. Ievins, Adrien Boissenin, Nicholas M. Tolley, Abed Khorasani, Sarah E. Mondello, Chet T. Moritz
Publikováno v:
Journal of neuroscience methods. 366
Although there is currently no cure for paralysis due to spinal cord injury (SCI), the highest treatment priority is restoring arm and hand function for people with cervical SCI. Preclinical animal models provide an opportunity to test innovative tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c02adc0a46c57ed79e94a2084ee6396
https://pubmed.ncbi.nlm.nih.gov/34863839
https://pubmed.ncbi.nlm.nih.gov/34863839
Autor:
Gregory D. Horwitz, Amanda E. Fischedick, Chet T. Moritz, Michael D. Sunshine, Sam J. Dreyer, Sarah E. Mondello, Polina Anikeeva, Philip J. Horner
Publikováno v:
Journal of Neurophysiology. 120:795-811
Electrical intraspinal microstimulation (ISMS) at various sites along the cervical spinal cord permits forelimb muscle activation, elicits complex limb movements and may enhance functional recovery after spinal cord injury. Here, we explore optogenet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71f27d281cc04f3aa0fe62ffdff5251
https://doi.org/10.1152/jn.00461.2017
https://doi.org/10.1152/jn.00461.2017
Publikováno v:
J Neurotrauma
Transfer of information across a spinal lesion is required for many aspects of recovery across diverse motor systems. Our understanding of axonal plasticity and which subpopulations of neurons may contribute to bridging substrates following injury, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a9d7ab9eab9c765f79b227776bfad3
https://pubmed.ncbi.nlm.nih.gov/31774025
https://pubmed.ncbi.nlm.nih.gov/31774025
Publikováno v:
J Neurosci Methods
Background Fluorogold (FG) is used by many groups to retrogradely trace nervous system pathways. Fluorogold, while a robust tracer, also is neurotoxic and causes tissue damage at the injection site and leads to motor deficits. New method In the curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54875fb82bafd0bc5d5b21b4f11c6a92
https://doi.org/10.1016/j.jneumeth.2016.06.004
https://doi.org/10.1016/j.jneumeth.2016.06.004
Autor:
Chet T. Moritz, Philip J. Horner, Amanda E. Fischedick, Sarah E. Mondello, B.D. Pedigo, Michael D. Sunshine
Publikováno v:
Exp Neurol
To date, relatively few studies have used optogenetic stimulation to address basic science and therapeutic questions within the spinal cord. Even less have reported optogenetic stimulation in the rat spinal cord. This is likely due to a lack of acces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6e2954c3fc6d403cc050e530ee9628
https://doi.org/10.1016/j.expneurol.2020.113480
https://doi.org/10.1016/j.expneurol.2020.113480
Autor:
Amanda E. Fischedick, Michael D. Sunshine, Chet T. Moritz, Philip J. Horner, Sarah E. Mondello
Publikováno v:
Journal of neurotrauma. 32(24)
Cervical spinal cord contusion is the most common human spinal cord injury, yet few rodent models replicate the pathophysiological and functional sequela of this injury. Here, we modified an electromechanical injury device and characterized the behav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002a25e3d8df0bebef5c3a843ef4e089
https://pubmed.ncbi.nlm.nih.gov/25929319
https://pubmed.ncbi.nlm.nih.gov/25929319
Autor:
Chet T. Moritz, Eun Ah Chang, Jose B. Cibelli, Samuel E. Nutt, Steven T. Suhr, Sarah E. Mondello, Philip J. Horner, Laura O. Schlosser
Publikováno v:
Experimental neurology. 248
Neural progenitor cells (NPCs) have shown modest potential and some side effects (e.g. allodynia) for treatment of spinal cord injury (SCI). In only a few cases, however, have NPCs shown promise at the chronic stage. Given the 1.275 million people li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fdf8901871fb9d91ed7b18dceba551a
https://pubmed.ncbi.nlm.nih.gov/23891888
https://pubmed.ncbi.nlm.nih.gov/23891888