Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Sarah E. McClelland"'
Autor:
Nadeem Shaikh, Alice Mazzagatti, Simone De Angelis, Sarah C. Johnson, Bjorn Bakker, Diana C. J. Spierings, René Wardenaar, Eleni Maniati, Jun Wang, Michael A. Boemo, Floris Foijer, Sarah E. McClelland
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-24 (2022)
Abstract Background A major driver of cancer chromosomal instability is replication stress, the slowing or stalling of DNA replication. How replication stress and genomic instability are connected is not known. Aphidicolin-induced replication stress
Externí odkaz:
https://doaj.org/article/605dfc366d034220a1dfc1ef067430aa
Publikováno v:
Molecular Cytogenetics, Vol 12, Iss 1, Pp 1-21 (2019)
Abstract Many cancers possess an incorrect number of chromosomes, a state described as aneuploidy. Aneuploidy is often caused by Chromosomal Instability (CIN), a process of continuous chromosome mis-segregation. CIN is believed to endow tumours with
Externí odkaz:
https://doaj.org/article/51e07b647894455c91fc83d94fe3dc60
Autor:
Laura Tovini, Sarah E. McClelland
Publikováno v:
Biomolecules, Vol 9, Iss 2, p 44 (2019)
It has recently emerged that human chromosomes vary between one another in terms of features that impact their behaviour during impaired chromosome segregation, leading to non-random aneuploidy in the daughter cell population. During the process of c
Externí odkaz:
https://doaj.org/article/c0b003e64f8f4568838e43554d5c586d
Autor:
Laura Tovini, Sarah C Johnson, Molly A Guscott, Alexander M Andersen, Diana Carolina Johanna Spierings, René Wardenaar, Floris Foijer, Sarah E McClelland
Publikováno v:
The EMBO Journal. 42(10)
Cancer cells display persistent underlying chromosomal instability, with individual tumour types intriguingly exhibiting characteristic subsets of whole, and subchromosomal aneuploidies. Few methods to induce specific aneuploidies will exist, hamperi
Autor:
Sarah E. McClelland, Kit Curtius, Jun Wang, Frances R. Balkwill, Catherine M. Green, Mary-Anne Durin, Daniela Moralli, Eleni Maniati, Jennifer R. McGuinness, Tanya N. Soliman, Daniel Muliaditan, Nadeem Shaikh, Naoka Tamura
RNA seq pathway analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67690e0b13e619347066864020b93530
https://doi.org/10.1158/0008-5472.22425388.v1
https://doi.org/10.1158/0008-5472.22425388.v1
Autor:
Sarah E. McClelland, Kit Curtius, Jun Wang, Frances R. Balkwill, Catherine M. Green, Mary-Anne Durin, Daniela Moralli, Eleni Maniati, Jennifer R. McGuinness, Tanya N. Soliman, Daniel Muliaditan, Nadeem Shaikh, Naoka Tamura
Movie of MT assembly rate assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714217f5b76eb1cc561df6e3a02c6503
https://doi.org/10.1158/0008-5472.22425400.v1
https://doi.org/10.1158/0008-5472.22425400.v1
Autor:
Sarah E. McClelland, Kit Curtius, Jun Wang, Frances R. Balkwill, Catherine M. Green, Mary-Anne Durin, Daniela Moralli, Eleni Maniati, Jennifer R. McGuinness, Tanya N. Soliman, Daniel Muliaditan, Nadeem Shaikh, Naoka Tamura
One supplemental movie, four supplemental tables, six supplemental figures, supplemental methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6566f6f1837e15d04f4078c6406fbc4e
https://doi.org/10.1158/0008-5472.22425403
https://doi.org/10.1158/0008-5472.22425403
Autor:
Sarah E. McClelland, Kit Curtius, Jun Wang, Frances R. Balkwill, Catherine M. Green, Mary-Anne Durin, Daniela Moralli, Eleni Maniati, Jennifer R. McGuinness, Tanya N. Soliman, Daniel Muliaditan, Nadeem Shaikh, Naoka Tamura
Chromosomal instability (CIN) comprises continual gain and loss of chromosomes or parts of chromosomes and occurs in the majority of cancers, often conferring poor prognosis. Because of a scarcity of functional studies and poor understanding of how g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd122023cd13740acfec05108e2c3bb
https://doi.org/10.1158/0008-5472.c.6512023
https://doi.org/10.1158/0008-5472.c.6512023
Autor:
Charles Swanton, Zoltan Szallasi, Andrea L. Richardson, Iain B. Tan, Patrick Tan, David Endesfelder, Sarah E. McClelland, Qiyuan Li, Aron C. Eklund, Nicolai J. Birkbak
Supplementary Table 1 from Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1656962ab8da98ab86827944886e3f7f
https://doi.org/10.1158/0008-5472.22388762.v1
https://doi.org/10.1158/0008-5472.22388762.v1
Autor:
Charles Swanton, Zoltan Szallasi, Andrea L. Richardson, Iain B. Tan, Patrick Tan, David Endesfelder, Sarah E. McClelland, Qiyuan Li, Aron C. Eklund, Nicolai J. Birkbak
Supplementary Figure 4 from Paradoxical Relationship between Chromosomal Instability and Survival Outcome in Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be149452f26c9118d62ca080d190d6d
https://doi.org/10.1158/0008-5472.22388774.v1
https://doi.org/10.1158/0008-5472.22388774.v1