Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sarah E. Martchenko"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The incretin hormone glucagon-like peptide-1 (GLP-1) is secreted by the intestinal L cell in response to nutrient intake. However, GLP-1 secretion also follows a circadian rhythm which is disrupted by the saturated fatty acid palmitate in vi
Externí odkaz:
https://doaj.org/article/554a69a92f394ceb889a286852583454
Autor:
Sarah E. Martchenko, David Prescott, Alexandre Martchenko, Maegan E. Sweeney, Dana J. Philpott, Patricia L. Brubaker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Intestinal functions demonstrate circadian rhythms thought to be entrained, in part, by an organisms’ intrinsic feeding and fasting periods as well as by the intestinal microbiome. Circadian disruption as a result of ill-timed nutrient exp
Externí odkaz:
https://doaj.org/article/df5c745531d4463cbc45706c3cba746e
Autor:
Sarah E. Martchenko, Alexandre Martchenko, Andrew D. Biancolin, Alison Waller, Patricia L. Brubaker
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101340- (2021)
Objective: Recent studies using whole-body clock-disrupted animals identified a disruption in the circadian rhythm of the intestinal L-cell incretin hormone, glucagon-like peptide-1 (GLP-1). Although GLP-1 plays an essential role in metabolism throug
Externí odkaz:
https://doaj.org/article/b12602626be544f7a8428e51c6fa81a9
Autor:
David Prescott, Sarah E. Martchenko, Maegan E. Sweeney, Dana J. Philpott, Patricia L. Brubaker, Alexandre Martchenko
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Intestinal functions demonstrate circadian rhythms thought to be entrained, in part, by an organisms’ intrinsic feeding and fasting periods as well as by the intestinal microbiome. Circadian disruption as a result of ill-timed nutrient exposure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d94dbf976a9e81f4be650df334c9059
http://europepmc.org/articles/PMC8523685
http://europepmc.org/articles/PMC8523685
Autor:
Patricia L. Brubaker, Alexandre Martchenko, Alison S. Waller, Andrew D. Biancolin, Sarah E. Martchenko
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 54, Iss, Pp 101340-(2021)
Molecular Metabolism, Vol 54, Iss, Pp 101340-(2021)
Objective Recent studies using whole-body clock-disrupted animals identified a disruption in the circadian rhythm of the intestinal L-cell incretin hormone, glucagon-like peptide-1 (GLP-1). Although GLP-1 plays an essential role in metabolism through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef4fd2a5480787f322152ac5e41d143
https://pubmed.ncbi.nlm.nih.gov/34520858
https://pubmed.ncbi.nlm.nih.gov/34520858
Publikováno v:
Diabetes. 70
Glucagon-like peptide-1 (GLP-1) is an incretin hormone released by the intestinal L cell in response to nutrient intake. Recent studies identified a circadian rhythm in GLP-1 secretion that is disrupted in whole-body Bmal1 KO mice. However, the exten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dd1605c0f3164de8149eafcd1e94b5d
https://doi.org/10.2337/db21-260-or
https://doi.org/10.2337/db21-260-or
Publikováno v:
Endocrinology
Circadian rhythms are 24-hour biological rhythms within organisms that have developed over evolutionary time due to predefined environmental changes, mainly the light-dark cycle. Interestingly, metabolic tissues, which are largely responsible for est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8a324a961f7fadb343e2e4c776dcd5
https://doi.org/10.1210/endocr/bqaa167
https://doi.org/10.1210/endocr/bqaa167
Autor:
Patricia L. Brubaker, Dana J. Philpott, Maegan E. Sweeney, Patrick Gurges, Alison Waller, Kendra Naismith, Brian J. Cox, Alexandre Martchenko, Sarah E. Martchenko, Ada Admin
The incretin, glucagon-like peptide-1 (GLP-1), is secreted by the intestinal L-cell upon nutrient ingestion. GLP-1 also exhibits a circadian rhythm, with highest release at the onset of the feeding period. Similarly, microbial composition and functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4edbb5536e279b8ad5bd14424dce13e7
https://doi.org/10.2337/figshare.12928334.v1
https://doi.org/10.2337/figshare.12928334.v1
Autor:
Brian J. Cox, Alison S. Waller, Sarah E. Martchenko, Maegan E. Sweeney, Patrick Gurges, Kendra Naismith, Dana J. Philpott, Patricia L. Brubaker, Alexandre Martchenko
Publikováno v:
Diabetes. 69(12)
The incretin glucagon-like peptide 1 (GLP-1) is secreted by the intestinal L cell upon nutrient ingestion. GLP-1 also exhibits a circadian rhythm, with highest release at the onset of the feeding period. Similarly, microbial composition and function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b630cbf1c1e288cead1b264846299a1
https://pubmed.ncbi.nlm.nih.gov/32928871
https://pubmed.ncbi.nlm.nih.gov/32928871
Autor:
Violetta Dimitriadou, Joseph A. Murray, Patricia L. Brubaker, Sarah E. Martchenko, Maegan E. Sweeney
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 373(3)
Long-acting glucagon-like peptide-2 receptor (GLP-2R) agonists are well-established to increase intestinal growth in rodents and, most notably, humans with short bowel syndrome. Most of the trophic effects of GLP-2R agonists are reported to be mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1966a489474d42b3f8a20ee1f9dd1562
https://pubmed.ncbi.nlm.nih.gov/32144124
https://pubmed.ncbi.nlm.nih.gov/32144124