Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sarah E. Little-Letsinger"'
Autor:
Cody McGrath, Sarah E. Little-Letsinger, Gabriel M. Pagnotti, Buer Sen, Zhihui Xie, Gunes Uzer, Guniz B. Uzer, Xiaopeng Zong, Martin A. Styner, Janet Rubin, Maya Styner
Publikováno v:
Obesity Facts, Pp 1-13 (2024)
Introduction: Longitudinal effect of diet-induced obesity on bone is uncertain. Prior work showed both no effect and a decrement in bone density or quality when obesity begins prior to skeletal maturity. We aimed to quantify long-term effects of obes
Externí odkaz:
https://doaj.org/article/e65a38454ea74e49b05eba95071a34e4
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The skeletal and immune systems are intricately intertwined within the bone marrow microenvironment, a field of study termed osteoimmunology. Osteoimmune interactions are key players in bone homeostasis and remodeling. Despite the critical role of th
Externí odkaz:
https://doaj.org/article/46fd003e48724f0caaeeb00b40f4e41a
Autor:
Cody McGrath, Sarah E. Little-Letsinger, Jeyantt Srinivas Sankaran, Buer Sen, Zhihui Xie, Martin A. Styner, Xiaopeng Zong, Weiqin Chen, Janet Rubin, Eric L. Klett, Rosalind A. Coleman, Maya Styner
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
Exercise, typically beneficial for skeletal health, has not yet been studied in lipodystrophy, a condition characterized by paucity of white adipose tissue, with eventual diabetes, and steatosis. We applied a mouse model of global deficiency of Bscl2
Externí odkaz:
https://doaj.org/article/90c8fb2686cb4275a153c4d436770c40
Autor:
Sarah E. Little-Letsinger, Ayland C. Letsinger, Jon P. Elizondo, Brianne M. Breidenbach, Harry A. Hogan, J. Timothy Lightfoot, Susan A. Bloomfield
Publikováno v:
Medicine & Science in Sports & Exercise.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b873265627c5eb0a2eba1e70e40b242
https://doi.org/10.1249/mss.0000000000003218
https://doi.org/10.1249/mss.0000000000003218
Autor:
Clinton T. Rubin, Maya Styner, Eric L. Klett, Sarah E. Little-Letsinger, Gabriel M. Pagnotti, Cody McGrath, Janet Rubin, Brian O. Diekman
Publikováno v:
Seminars in Cell & Developmental Biology. 123:22-35
Aging induces alterations in bone structure and strength through a multitude of processes, exacerbating common aging- related diseases like osteoporosis and osteoarthritis. Cellular hallmarks of aging are examined, as related to bone and the marrow m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3679ffc92695acdf74fb924b8b9d29ab
https://doi.org/10.1016/j.semcdb.2021.08.011
https://doi.org/10.1016/j.semcdb.2021.08.011
Autor:
AYLAND C. LETSINGER, FANG YANG, RANI MENON, SARAH E. LITTLE-LETSINGER, JORGE Z. GRANADOS, BRIANNE BREIDENBACH, ANJUSHREE R. IYER, TATIANA CASTRO PADOVANI, EDWARD C. NAGEL, ARUL JAYARAMAN, J. TIMOTHY LIGHTFOOT
Publikováno v:
Medicine and science in sports and exercise. 54(9)
Chronic overfeeding via a high-fat/high-sugar (HFHS) diet decreases wheel running and substantially alters the gut metabolome of C57BL/6J mice. In this study, we tested the hypothesis that fecal microbial transplants can modulate the effect of diet o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4612538ef7c3d4a18ba0b4ff6fcf182
https://pubmed.ncbi.nlm.nih.gov/35969165
https://pubmed.ncbi.nlm.nih.gov/35969165
Publikováno v:
J Appl Physiol (1985)
Chronic inflammation leads to bone loss and fragility. Proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) consistently promote bone resorption. Dietary modulation of proinflammatory cytokines is an accepted therapeutic approach to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bd8318a955829a078497656429ce6b
https://doi.org/10.1152/japplphysiol.00848.2020
https://doi.org/10.1152/japplphysiol.00848.2020
Autor:
Sarah E. Little-Letsinger, Zhihui Xie, Maya Styner, Cody McGrath, Amel Dudakovic, Janet Rubin, Buer Sen, Andre J. van Wijnen, Jeyantt S. Sankaran
Publikováno v:
JBMR Plus
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
Use of the selective estrogen receptor modulator Tamoxifen (TAM) is a mainstay to induce conditional expression of Cre recombinase in transgenic laboratory mice. To excise β‐cateninfl/fl in 28‐day‐old male and female Prrx1‐CreER/β‐catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c1bec988d0de26592641a970824d13
https://doi.org/10.1002/jbm4.10450
https://doi.org/10.1002/jbm4.10450
Autor:
Buer Sen, Janet Rubin, Amel Dudakovic, Cody McGrath, Zhihui Xie, Maya Styner, Sarah E. Little-Letsinger, Andre J. Wijnen, Jeyantt S. Sankaran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::113879552003d8b8b5b250c94503ebe8
https://doi.org/10.1002/jbm4.10450/v2/response1
https://doi.org/10.1002/jbm4.10450/v2/response1
Publikováno v:
Curr Osteoporos Rep
PURPOSE OF REVIEW: To highlight recent basic, translational, and clinical work demonstrating exercise and diet regulation of marrow adipose tissue (MAT) and bone, and how this informs current understanding of the relationship between marrow adiposity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af684244ae6639ddedeafa52d04174ee
https://pubmed.ncbi.nlm.nih.gov/33068251
https://pubmed.ncbi.nlm.nih.gov/33068251