Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sarah E. Little-Letsinger"'
Autor:
Cody McGrath, Sarah E. Little-Letsinger, Gabriel M. Pagnotti, Buer Sen, Zhihui Xie, Gunes Uzer, Guniz B. Uzer, Xiaopeng Zong, Martin A. Styner, Janet Rubin, Maya Styner
Publikováno v:
Obesity Facts, Pp 1-13 (2024)
Introduction: Longitudinal effect of diet-induced obesity on bone is uncertain. Prior work showed both no effect and a decrement in bone density or quality when obesity begins prior to skeletal maturity. We aimed to quantify long-term effects of obes
Externí odkaz:
https://doaj.org/article/e65a38454ea74e49b05eba95071a34e4
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The skeletal and immune systems are intricately intertwined within the bone marrow microenvironment, a field of study termed osteoimmunology. Osteoimmune interactions are key players in bone homeostasis and remodeling. Despite the critical role of th
Externí odkaz:
https://doaj.org/article/46fd003e48724f0caaeeb00b40f4e41a
Autor:
Sarah E Little-Letsinger
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0288212 (2023)
A reliable, widely available method to detect osteoporosis prior to fracture is needed. Serum levels of C-reactive protein may independently predict low bone mineral density (BMD) and high fracture risk. Existing empirical data focus on sexually and/
Externí odkaz:
https://doaj.org/article/b4c8dfbd0cfb4846b15d172bd8ad4683
Autor:
Cody McGrath, Sarah E. Little-Letsinger, Jeyantt Srinivas Sankaran, Buer Sen, Zhihui Xie, Martin A. Styner, Xiaopeng Zong, Weiqin Chen, Janet Rubin, Eric L. Klett, Rosalind A. Coleman, Maya Styner
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
Exercise, typically beneficial for skeletal health, has not yet been studied in lipodystrophy, a condition characterized by paucity of white adipose tissue, with eventual diabetes, and steatosis. We applied a mouse model of global deficiency of Bscl2
Externí odkaz:
https://doaj.org/article/90c8fb2686cb4275a153c4d436770c40
Autor:
Sarah E. Little-Letsinger, Ayland C. Letsinger, Jon P. Elizondo, Brianne M. Breidenbach, Harry A. Hogan, J. Timothy Lightfoot, Susan A. Bloomfield
Publikováno v:
Medicine & Science in Sports & Exercise.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b873265627c5eb0a2eba1e70e40b242
https://doi.org/10.1249/mss.0000000000003218
https://doi.org/10.1249/mss.0000000000003218
Autor:
Clinton T. Rubin, Maya Styner, Eric L. Klett, Sarah E. Little-Letsinger, Gabriel M. Pagnotti, Cody McGrath, Janet Rubin, Brian O. Diekman
Publikováno v:
Seminars in Cell & Developmental Biology. 123:22-35
Aging induces alterations in bone structure and strength through a multitude of processes, exacerbating common aging- related diseases like osteoporosis and osteoarthritis. Cellular hallmarks of aging are examined, as related to bone and the marrow m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3679ffc92695acdf74fb924b8b9d29ab
https://doi.org/10.1016/j.semcdb.2021.08.011
https://doi.org/10.1016/j.semcdb.2021.08.011
Autor:
AYLAND C. LETSINGER, FANG YANG, RANI MENON, SARAH E. LITTLE-LETSINGER, JORGE Z. GRANADOS, BRIANNE BREIDENBACH, ANJUSHREE R. IYER, TATIANA CASTRO PADOVANI, EDWARD C. NAGEL, ARUL JAYARAMAN, J. TIMOTHY LIGHTFOOT
Publikováno v:
Medicine and science in sports and exercise. 54(9)
Chronic overfeeding via a high-fat/high-sugar (HFHS) diet decreases wheel running and substantially alters the gut metabolome of C57BL/6J mice. In this study, we tested the hypothesis that fecal microbial transplants can modulate the effect of diet o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4612538ef7c3d4a18ba0b4ff6fcf182
https://pubmed.ncbi.nlm.nih.gov/35969165
https://pubmed.ncbi.nlm.nih.gov/35969165
Publikováno v:
J Appl Physiol (1985)
Chronic inflammation leads to bone loss and fragility. Proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) consistently promote bone resorption. Dietary modulation of proinflammatory cytokines is an accepted therapeutic approach to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bd8318a955829a078497656429ce6b
https://doi.org/10.1152/japplphysiol.00848.2020
https://doi.org/10.1152/japplphysiol.00848.2020
Autor:
Sarah E. Little-Letsinger, Zhihui Xie, Maya Styner, Cody McGrath, Amel Dudakovic, Janet Rubin, Buer Sen, Andre J. van Wijnen, Jeyantt S. Sankaran
Publikováno v:
JBMR Plus
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
Use of the selective estrogen receptor modulator Tamoxifen (TAM) is a mainstay to induce conditional expression of Cre recombinase in transgenic laboratory mice. To excise β‐cateninfl/fl in 28‐day‐old male and female Prrx1‐CreER/β‐catenin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c1bec988d0de26592641a970824d13
https://doi.org/10.1002/jbm4.10450
https://doi.org/10.1002/jbm4.10450
Autor:
Buer Sen, Janet Rubin, Amel Dudakovic, Cody McGrath, Zhihui Xie, Maya Styner, Sarah E. Little-Letsinger, Andre J. Wijnen, Jeyantt S. Sankaran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::113879552003d8b8b5b250c94503ebe8
https://doi.org/10.1002/jbm4.10450/v2/response1
https://doi.org/10.1002/jbm4.10450/v2/response1
