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pro vyhledávání: '"Sarah E. Hosch"'
Autor:
Tyler M. Parsons, Katie L. Buelow, Alaa Hanna, Marisa A. Brake, Crystal Poma, Sarah E. Hosch, Randal J. Westrick, Luis G. Villa-Diaz, George D. Wilson, Gerard J. Madlambayan
Publikováno v:
Br J Cancer
BACKGROUND: Bone-marrow-derived haematopoietic stem and progenitor cells (HSPCs) are a prominent part of the highly complex tumour microenvironment (TME) where they localise within tumours and maintain haematopoietic potency. Understanding the role H
Autor:
Carey N. Lumeng, Sarah E. Hosch, Mohammad Pashmforoush, Jaap G. Neels, Lisa A. Lesniewski, Miriam Scadeng, Carl de Luca, Alan R. Saltiel, Jerrold M. Olefsky, Shian Huey Chiang
Publikováno v:
Nature medicine. 13(4)
Cbl-associated protein (Cap) is a member of a phosphatidylinositol 3-kinase-independent pathway for insulin-stimulated translocation of the glucose transporter GLUT4. Despite this positive role of Cap in glucose uptake, here we show that deletion of
Publikováno v:
Cell Metabolism. 4:5-6
Adiponectin, an adipocyte secretory hormone, has been causally linked to insulin resistance in the metabolic syndrome and diabetes. A recent paper (Mao et al., 2006) shows that the APPL1 adaptor protein binds to the intracellular domain of adiponecti