Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sarah E. Goulding"'
Publikováno v:
J Cell Sci
The chromosomal passenger protein complex has emerged as a key player in mitosis, with important roles in chromatin modifications, kinetochore-microtubule interactions, chromosome bi-orientation and stability of the bipolar spindle, mitotic checkpoin
Publikováno v:
Journal of Cell Science. 116:4715-4726
DNA topoisomerase II (Topo II) is a major component of mitotic chromosomes and an important drug target in cancer chemotherapy, however, its role in chromosome structure and dynamics remains controversial. We have used RNAi to deplete Topo II in Dros
Publikováno v:
Molecular Biology of the Cell. 12:2308-2327
We provide a detailed description of Golgi stack biogenesis that takes place in vivo during one of the morphogenetic events in the lifespan of Drosophila melanogaster. In early third-instar larvae, small clusters consisting mostly of vesicles and tub
Publikováno v:
Developmental Biology. 221(1):120-131
In Drosophila neurogenesis, proneural genes encode bHLH proteins that are required for neural precursor selection. But many vertebrate homologues are expressed later and are postulated to have multiple roles during neurogenesis. We have isolated a ne
Publikováno v:
Neuron. 25:69-78
In a variety of organisms, early neurogenesis requires the function of basic-helix-loop-helix (bHLH) transcription factors. For the Drosophila PNS, such transcription factors are encoded by the proneural genes (atonal and the achaete–scute complex,
Publikováno v:
Yeast. 12:999-1004
We report a 29,445 bp sequence from the right arm of yeast chromosome XV. It contains the genes MYO2, SNC2, PDR10, SCD5 (also called FTB1), MIP1, VMA4, MRS2, ALA1, KRE5, TEA1, and a homologue of YAL034c. Several discrepancies with previously publishe
Publikováno v:
Molecular and General Genetics MGG. 252:195-206
The endpoints of the large inverted repeat (IR) of chloroplast DNA in flowering plants differ by small amounts between species. To quantify the extent of this movement and define a possible mechanism for IR expansion, DNA sequences across the IR-larg
Autor:
William C. Earnshaw, Sarah E. Goulding
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 27(6)
To ensure accurate chromosome segregation during mitosis, the spindle checkpoint monitors chromosome alignment on the mitotic spindle. Indjeian and colleagues have investigated the precise role of the shugoshin 1 protein (Sgo1p) in this process in bu