Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sarah E. Glazer"'
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Traditionally, immunotherapy agent selection and treatment strategies are guided by biopsy-based histological information. However, biopsies are limited in that they are invasive, provide static information regarding the tumor immune microenvironment
Externí odkaz:
https://doaj.org/article/3935760ddf504351af89200c37e2dea0
Autor:
Margie N. Sutton, Sarah E. Glazer, Riccardo Muzzioli, Ping Yang, Seth T. Gammon, David Piwnica-Worms
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract B7-H3 (CD276) has two isoforms (2Ig and 4Ig), no confirmed cognate receptor, and physiological functions that remain elusive. While differentially expressed on many solid tumors correlating with poor survival, mechanisms of how B7-H3 signals
Externí odkaz:
https://doaj.org/article/04ec9168b1b746a6b5ec8181d0f2e8fa
Autor:
Bhasker Radaram, Sarah E. Glazer, Ping Yang, Chia-Wei Li, Mien-Chie Hung, Seth T. Gammon, Mian Alauddin, David Piwnica-Worms
Publikováno v:
ACS Omega. 8:17181-17194
Autor:
Margie Nicole Sutton, Sarah E. Glazer, Riccardo Muzzioli, Ping Yang, Seth T. Gammon, David Piwnica-Worms
Publikováno v:
Cancer Research. 83:6416-6416
B7-H3 (CD276) is a member of the B7 family of immune regulators, but unlike the immune checkpoint targets that have revolutionized cancer therapy, blockade has resulted in mixed outcomes. B7-H3 has 2Ig and 4Ig isoforms, has no known direct ligand, an