Výsledky vyhledávání - "Sarah E. Gibbons"

Development of an online drug-drug interaction resource to support safe prescription of oncolytics

Autor: Jasmine L.M. Martin, Sarah E. Gibbons, K. McAllister, David M. Burger, Saye Khoo, Nielka P. van Erp, Kaylee R.M. Ferrier, Nienke A.G. Lankheet, Frank G A Jansman

Publikováno v: Journal of Clinical Oncology, 36(15 suppl.):e18574. AMER SOC CLINICAL ONCOLOGY

e18574Background: Patients treated for cancer are at high risk of drug-drug interactions (DDI), which affects nearly 60% of patients on therapy. We developed a freely available DDI resource (www.ca...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7f5ce204ee431ecff01181c9ee3a71
https://doi.org/10.1200/jco.2018.36.15_suppl.e18574

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Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen

Autor: Susan M. Drake, Erasmus Smit, Sarah E. Gibbons, David Back, Patricia A. Cane, Adil Isaac, David White, Saye Khoo, Stephen Taylor

Publikováno v: Journal of Antimicrobial Chemotherapy. 54:498-502

To evaluate the steady-state blood plasma (BP), CSF and seminal plasma (SP) pharmacokinetics (PK) of twice-daily indinavir 400 mg and lopinavir/ritonavir.Ten HIV-1-positive men on lopinavir/ritonavir participated in a PK study. PK sampling was perfor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2be61b86ca57007892d6bc4b41cdd0
https://doi.org/10.1093/jac/dkh357

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Dose escalation or immediate full dose when switching from efavirenz to nevirapine-based highly active antiretroviral therapy in HIV-1-infected individuals?

Autor: Sarah E. Gibbons, Sundhiya Mandalia, Anton Pozniak, David Back, Darmishta Parmar, Mark T. Nelson, Nicola Smith, Brian Gazzard, Carl Fletcher, Alan Winston

Publikováno v: AIDS. 18:572-574

Efavirenz induces the metabolism of co-administered drugs through the induction of CYP 3A4. It is often necessary to switch from efavirenz to nevirapine because of intolerance or toxicity. In a pharmacokinetic study we determined whether to dose-esca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b6d51ded73a95e7d896af19ca335fa
https://doi.org/10.1097/00002030-200402200-00029

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Akademický článek

Lopinavir/ritonavir combined with twice-daily 400 mg indinavir: pharmacokinetics and pharmacodynamics in blood, CSF and semen.

Autor: Adil Isaac, Stephen Taylor, Patricia Cane, Erasmus Smit, Sarah E. Gibbons, David J. White, Susan M. Drake, Saye Khoo, David J. Back

Publikováno v: Journal of Antimicrobial Chemotherapy (JAC); Aug2004, Vol. 54 Issue 2, p498-502, 5p

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