Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sarah E. Cleary"'
Autor:
Daria Sokolova, Tara C. Lurshay, Jack S. Rowbotham, Georgia Stonadge, Holly A. Reeve, Sarah E. Cleary, Tim Sudmeier, Kylie A. Vincent
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Cleaner synthesis of amines remains a key challenge in organic chemistry because of their prevalence in pharmaceuticals, agrochemicals and synthetic building blocks. Here, we report a different paradigm for chemoselective hydrogenation of ni
Externí odkaz:
https://doaj.org/article/8edcc78d71dd4cfc9cd2538d818cff90
Autor:
Sarah E. Cleary, Sofia Kazantzi, Joshua A. Trenchard, Martin Monedero, Jack W. Allman, Tara C. Lurshay, Xu Zhao, Michael B. C. Kenny, Holly A. Reeve
Publikováno v:
Frontiers in Catalysis, Vol 3 (2023)
Introduction: This work was carried out to understand if a heterogeneous biocatalytic hydrogenation system could be implemented in a slurry mode continuous flow reactor, as a “slot-in” alternative to a metal/carbon catalyst with minimal process o
Externí odkaz:
https://doaj.org/article/90770aebfeba40f59bb5f9e04e0c55a4
Autor:
Miguel A. Ramirez, Shiny Joseph Srinivasan, Sarah E. Cleary, Peter M. T. Todd, Holly A. Reeve, Kylie A. Vincent
Publikováno v:
Frontiers in Catalysis, Vol 2 (2022)
Hydrogenase-mediated reduction of flavin mononucleotide by H2 is exploited to enable cleaner application of nitroreductase enzymes for reduction of aromatic nitro functional groups. This turns the overall reaction into a biocatalytic hydrogenation. U
Externí odkaz:
https://doaj.org/article/db6d00e74b944c4ea118b2308a13893a
Publikováno v:
Frontiers in Chemical Engineering, Vol 3 (2021)
Translation of redox biocatalysis into a commercial hydrogenation flow reactor, with in-built electrolytic H2 generation, was achieved using immobilized enzyme systems. Carbon-supported biocatalysts were first tested in batch mode, and were then tran
Externí odkaz:
https://doaj.org/article/8d75439194f1431c857625154a81d777
Autor:
Yasmin, Raya Al Maskari, Carmel M. McEniery, Sarah E. Cleary, Ye Li, Keith Siew, Nichola L. Figg, Ashraf W. Khir, John R. Cockcroft, Ian B. Wilkinson, Kevin M. O’Shaughnessy
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Stiffening of the aorta is an important independent risk factor for myocardial infarction and stroke. Yet its genetics is complex and little is known about its molecular drivers. We have identified for the first time, tagSNPs in the genes fo
Externí odkaz:
https://doaj.org/article/f4f9722e6a394997bed126349eb17c39
Publikováno v:
J Org Chem
The Lewis acid-promoted generation of destabilized vinyl cations from β-hydroxy diazo ketones leads to an energetically favorable 1,2-shift across the alkene followed by an irreversible C-H insertion to give cyclopentenone products. This reaction se
Publikováno v:
Frontiers in Chemical Engineering, Vol 3 (2021)
Translation of redox biocatalysis into a commercial hydrogenation flow reactor, with in-built electrolytic H2 generation, was achieved using immobilized enzyme systems. Carbon-supported biocatalysts were first tested in batch mode, and were then tran
Publikováno v:
Children and Youth Services Review. 88:205-210
Recruitment and retention of foster parents, as well as the potential for disruption and dissolution of adoptions, pose significant problems for child welfare systems and the well-being of children they serve. Parent satisfaction and commitment are t
Publikováno v:
Journal of Public Child Welfare. 12:492-513
High rates of children involved with the child welfare system are prescribed psychotropics. In response, federal legislation has mandated state child welfare agencies to develop policies to improve...
Publikováno v:
Chemical Science. 8:6810-6814
We report a Lewis acid catalyzed reaction sequence involving a 1,2-shift and subsequent C-H insertion that gives monocyclic and fused bicyclic cyclopentenone products. This reaction sequence, which is initiated by treating β-hydroxy-α-diazo ketones