Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sarah E. Bergholtz"'
Autor:
Sarah E Bergholtz, Sophia R Kurnot, Melissa DeJonckheere, Sarah T Hawley, Scott R Owens, Cathryn J Lapedis
Publikováno v:
American Journal of Clinical Pathology. 159:437-447
Objectives To characterize the attitudes of treating clinicians toward pathology explanation clinics (PECs). Methods Clinicians from a tertiary care academic medical center were asked, “How interested would you be in having your patient meet with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a26f945cd657d86e0d29b55c24b6b3d
https://doi.org/10.1093/ajcp/aqac175
https://doi.org/10.1093/ajcp/aqac175
Autor:
W. Marston Linehan, Daniel R. Crooks, Sarah E. Bergholtz, Youfeng Yang, Daniel W. Bak, Bhargav Srinivas Arimilli, Eranthie Weerapana, Jordan L. Meier, Minervo Perez
Publikováno v:
J Biol Chem
An important context in which metabolism influences tumorigenesis is the genetic cancer syndrome hereditary leiomyomatosis and renal cell carcinoma (HLRCC), a disease in which mutation of the tricarboxylic acid cycle enzyme fumarate hydratase (FH) ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ffd15cce25c684298a84c21bee956e3
https://doi.org/10.1074/jbc.ac120.014993
https://doi.org/10.1074/jbc.ac120.014993
Autor:
Sarah E. Bergholtz, Anthony Omole, Yihang Jing, Thomas Zengeya, Jordan L. Meier, Euna Yoo, Rhushi A. Kulkarni
Publikováno v:
Chembiochem
Lysine malonylation is a recently characterized posttranslational modification involved in the regulation of energy metabolism and gene expression. One unique feature of this posttranslational modification is its potential susceptibility to decarboxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf31f42b3af0ed5589e9a696280dc3f
https://europepmc.org/articles/PMC10262540/
https://europepmc.org/articles/PMC10262540/
Autor:
Chandrasekhar Mushti, W. Marston Linehan, Sarah E. Bergholtz, Daniel R. Crooks, Stephen J. Lockett, Jordan L. Meier, Andrew N. Lane, Chloe A. Briney, Rolf E. Swenson, Teresa W.-M. Fan, Rhushikesh A. Kulkarni
Publikováno v:
Chembiochem
Dysregulated metabolism can fuel cancer by altering the production of bioenergetic building blocks and directly stimulating oncogenic gene expression programs. However, relatively few optical methods for the direct study of metabolites in cells exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6353c0f687f5f886003f7d495884a4
https://doi.org/10.1002/cbic.201800651
https://doi.org/10.1002/cbic.201800651
Lysine malonylation is a recently characterized posttranslational modification involved in the regulation of energy metabolism and gene expression. Two unique features of this posttranslational modification are its negative charge and potential susce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f51ee5571fe3e4b234a92dbbbd3b5e0
https://doi.org/10.1101/2020.08.23.263285
https://doi.org/10.1101/2020.08.23.263285
Autor:
Sarah E. Bergholtz, Daniel W. Bak, Youfeng Yang, W. Marston Linehan, Minervo Perez, Jordan L. Meier, Eranthie Weerapana, Daniel R. Crooks
Metabolism and signaling intersect in the genetic cancer syndrome hereditary leiomyomatosis and renal cell carcinoma (HLRCC), a disease in which mutation of the TCA cycle enzyme fumarate hydratase (FH) causes hyperaccumulation of fumarate. This elect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a14a67594aea988add9b2bdd24411f59
https://doi.org/10.1101/2020.06.25.171843
https://doi.org/10.1101/2020.06.25.171843
Autor:
W. Marston Linehan, Susana S. Najera, Chloe A. Briney, Sarah E. Bergholtz, Jordan L. Meier, Minervo Perez
Publikováno v:
ACS Chem Biol
Metabolites regulate protein function via covalent and non-covalent interactions. However, manipulating these interactions in living cells remains a major challenge. Here we report a chemical strategy for inducing cysteine S-succination, a non-enzyma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30cf262dda0ca54f2b1b292361d3e91d
https://doi.org/10.1101/2020.01.11.902973
https://doi.org/10.1101/2020.01.11.902973
Autor:
Stephen D. Fox, Michael P. Washburn, Laurence Florens, Abigail L. Thorpe, Sarah E. Bergholtz, Jose L Montano, Thorkell Andresson, Jordan L. Meier, Mihaela E. Sardiu, Kellie D. Nance, Qishan Lin, Michaella J. Levy, David C. Montgomery
Publikováno v:
Cell Chem Biol
The plant cell cycle is tightly regulated by factors that integrate endogenous cues and environmental signals to adapt plant growth to changing conditions. Under drought, cell division in young leaves is blocked by an active mechanism, reducing the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d08368445f1a8fab7a08e3060173edd
https://europepmc.org/articles/PMC8237707/
https://europepmc.org/articles/PMC8237707/
Autor:
Eranthie Weerapana, Chloe A. Briney, Arissa E Bavari, Laurence Florens, Sarah E. Bergholtz, Rhushikesh A. Kulkarni, Michaella J. Levy, Michael P. Washburn, Daniel W. Bak, Darmood Wei, Aktan Alpsoy, Jonathan H. Shrimp, W. Marston Linehan, Emily C. Dykhuizen, Jordan L. Meier, Abigail L. Thorpe, Norma Frizzell
Hereditary cancer disorders often provide an important window into novel mechanisms supporting tumor growth and survival. Understanding these mechanisms and developing biomarkers to identify their presence thus represents a vital goal. Towards this g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5640889de2c600f3be01fa9c0a596f25
Autor:
Rhushikesh A. Kulkarni, Sarah E. Bergholtz, Daniel W. Bak, Chloe A. Briney, Jordan L. Meier, W. Marston Linehan, Eranthie Weerapana, David Wei, Jonathan H. Shrimp
Publikováno v:
Cancer Research. 79:2759-2759
Dysregulated metabolism is a feature of many diseases, including cancer. In addition to providing energy and building blocks to growing cells, altered metabolism can assist in tumor growth by producing “oncometabolites”. For example, in hereditar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70c2217d435cc9e55e6b35620eb71dfd
https://doi.org/10.1158/1538-7445.am2019-2759
https://doi.org/10.1158/1538-7445.am2019-2759