Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sarah E van Rossum-Fikkert"'
Autor:
Maarten W Paul, Arshdeep Sidhu, Yongxin Liang, Sarah E van Rossum-Fikkert, Hanny Odijk, Alex N Zelensky, Roland Kanaar, Claire Wyman
Publikováno v:
eLife, Vol 10 (2021)
Breast cancer type two susceptibility protein (BRCA2) is an essential protein in genome maintenance, homologous recombination (HR), and replication fork protection. Its function includes multiple interaction partners and requires timely localization
Externí odkaz:
https://doaj.org/article/b6b37d495f8f43f28cdbe0c08ec1c3b6
Autor:
Humberto Sanchez, Sarah E van Rossum-Fikkert, Nick L L van der Zon, Claire Wyman, Bram Verhagen, Malgorzata Grosbart, Arshdeep Sidhu, Dejan Ristic
Publikováno v:
Nucleic Acids Research
Nucleic acids research, 48(17)
Nucleic Acids Research, 48(17), 9649-9659. Oxford University Press
Nucleic acids research, 48(17)
Nucleic Acids Research, 48(17), 9649-9659. Oxford University Press
BRCA2 is a key breast cancer associated protein that is predicted to have interspersed regions of intrinsic disorder. Intrinsic disorder coupled with large size likely allows BRCA2 to sample a broad range of conformational space. We expect that the r
Autor:
Maarten W. Paul, Claire Wyman, Yongxin Liang, Roland Kanaar, Hanny Odijk, Sarah E van Rossum-Fikkert, Arshdeep Sidhu, Alex N. Zelensky
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28befe30d4df0f904f14a6d0bf2b6eb9
https://doi.org/10.7554/elife.67926.sa2
https://doi.org/10.7554/elife.67926.sa2
Autor:
Roland Kanaar, Claire Wyman, Hanny Odijk, Arshdeep Sidhu, Sarah E van Rossum-Fikkert, Yongxin Liang, Maarten W. Paul, Alex N. Zelensky
Publikováno v:
eLife
eLife, 10:e67926. eLife Sciences Publications
eLife, Vol 10 (2021)
eLife, 10:e67926. eLife Sciences Publications
eLife, Vol 10 (2021)
Breast cancer type two susceptibility protein (BRCA2) is an essential protein in genome maintenance, homologous recombination (HR), and replication fork protection. Its function includes multiple interaction partners and requires timely localization
Autor:
Claire Wyman, Maarten W. Paul, Sarah E van Rossum-Fikkert, Alex N. Zelensky, Arshdeep Sidhu, Roland Kanaar, Hanny Odijk, Yongxin Liang
BRCA2 is an essential protein in genome maintenance, homologous recombination and replication fork protection. Its function includes multiple interaction partners and requires timely localization to relevant sites in the nucleus. We investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4cb9bb0470c876f422d65a79ff68e6
https://doi.org/10.1101/2021.03.02.433541
https://doi.org/10.1101/2021.03.02.433541
Autor:
Humberto Sanchez, Claire Wyman, Sarah E van Rossum-Fikkert, Maarten W. Paul, Malgorzata Grosbart, Adriaan B Houtsmuller, Joyce H.G. Lebbink, Roland Kanaar
Publikováno v:
Nucleic Acids Research, 45(8), 4507-4518. Oxford University Press
Nucleic Acids Research
Nucleic Acids Research
The tumor suppressor BRCA2 is a large multifunctional protein mutated in 50–60% of familial breast cancers. BRCA2 interacts with many partners and includes multiple regions with potentially disordered structure. In homology directed DNA repair BRCA
Autor:
Claire Wyman, Iztok Vidic, Alex N. Zelensky, Dejan Ristic, Sarah E. van Rossum-Fikkert, Humberto Sanchez, Roland Kanaar, Jeroen Essers
Publikováno v:
Nucleic Acids Research; Vol 41
Nucleic Acids Research
Nucleic Acids Research, 41(13), 6475-6489. Oxford University Press
Nucleic Acids Research
Nucleic Acids Research, 41(13), 6475-6489. Oxford University Press
Caffeine is a widely used inhibitor of the protein kinases that play a central role in the DNA damage response. We used chemical inhibitors and genetically deficient mouse embryonic stem cell lines to study the role of DNA damage response in stable i
Autor:
Byron E. E. Martina, Nic Masters, Akbar Dastjerdi, Víctor Rodríguez Prieto, Albert D. M. E. Osterhaus, Willem Schaftenaar, Sarah Chapman, Lauren L. Howard, Paul D. Ling, Sarah E. van Rossum-Fikkert, Erin Latimer, Petra B. van den Doel
Publikováno v:
BMC Public Health
Background: Elephants are classified as critically endangered animals by the International Union for Conservation of Species (IUCN). Elephant endotheliotropic herpesvirus (EEHV) poses a large threat to breeding programs of captive Asian elephants by
Autor:
Byron E. E. Martina, Petra B. van den Doel, Nic Masters, Víctor Rodríguez Prieto, Erin Latimer, Sarah E. van Rossum-Fikkert, Lauren L. Howard, Paul D. Ling, Akbar Dastjerdi, Albert D. M. E. Osterhaus, Sarah Chapman, Willem Schaftenaar
Publikováno v:
BMC Veterinary Research
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
BMC Veterinary Research, 11. BioMed Central Ltd.
E-Prints Complutense. Archivo Institucional de la UCM
instname
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
BMC Veterinary Research, 11. BioMed Central Ltd.
E-Prints Complutense. Archivo Institucional de la UCM
instname
Background Elephants are classified as critically endangered animals by the International Union for Conservation of Species (IUCN). Elephant endotheliotropic herpesvirus (EEHV) poses a large threat to breeding programs of captive Asian elephants by c
Autor:
Eri Kinoshita, Claire Wyman, Humberto Sanchez, Aryandi Kertokalio, Sarah E. van Rossum-Fikkert
Publikováno v:
Biochimie, 113C, 47-53. Elsevier
The MRE11-RAD50-NBS1 (MRN) complex has several distinct functions in DNA repair including important roles in both non-homologous end-joining (NHEJ) and homologous recombination (HR). The biochemical activities of MR(N) have been well characterized im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dec84664465e58f5b7a912cc8984e88
https://pure.eur.nl/en/publications/2d49fe03-257d-43bb-bb39-572183443506
https://pure.eur.nl/en/publications/2d49fe03-257d-43bb-bb39-572183443506