E002 Management of adults with systemic lupus erythematosus (SLE) in 2021: a multi-centre audit within Wales as part of an ongoing quality improvement exercise

Autor: Sarah E Wright, Patrick O'Beirn, Ceril Rhys-Dillon

Publikováno v: Rheumatology. 62

Background/Aims Significant changes to working practices within rheumatology have occurred since the beginning of the COVID-19 pandemic: virtual consultations have now become commonplace. This audit was undertaken as part of ongoing quality improveme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::119ce4fe457c937973270c89d22a5cb5
https://doi.org/10.1093/rheumatology/kead104.251

Conformational Change in Molecular Crystals: Impact of Solvate Formation and Importance of Conformational Free Energies

Autor: Sarah E. Wright, Jason C. Cole, Aurora J. Cruz-Cabeza

Publikováno v: Wright, S E, Cole, J C & Cruz-cabeza, A J 2021, ' Conformational Change in Molecular Crystals: Impact of Solvate Formation and Importance of Conformational Free Energies ', Crystal Growth & Design . https://doi.org/10.1021/acs.cgd.1c00833

Changes in molecular conformation and its relationship with crystal polymorphism have been well documented in previous work. To the best of our knowledge, however, the effect of solvate formation on molecular conformation has never been explored. Usi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774764ce66f7f71e9d41107f78998a20
https://doi.org/10.1021/acs.cgd.1c00833

Transforming Computed Energy Landscapes into Experimental Realities: The Role of Structural Rugosity

Autor: Riccardo Montis, Aurora J. Cruz-Cabeza, Roger J. Davey, Grahame Woollam, Sarah E. Wright

Publikováno v: Cruz-cabeza, A J, Montis, R, Davey, R J, Wright, S E & Woollam, G R 2020, ' Transforming Computed Energy Landscapes into Experimental Realities – the Role of Structural Rugosity ', Angewandte Chemie International Edition, vol. 59, no. 46, pp. 20357-20360 . https://doi.org/10.1002/anie.202006939
Angewandte Chemie (International Ed. in English)

We exploit the possible link between structural surface roughness and difficulty of crystallisation. Polymorphs with smooth surfaces may nucleate and crystallise more readily than polymorphs with rough surfaces. The concept is applied to crystal stru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002c139840877a1f8983a85a9787c9a3
https://doi.org/10.1002/ange.202006939

Can solvated intermediates inform us about nucleation pathways? The case of β-pABA

Autor: David H. Bowskill, H. Abdullahi, D. Tulegenov, E. Taylor, Sarah E. Wright, Ghazala Sadiq, Isaac J. Sugden, Roger J. Davey, Aurora J. Cruz-Cabeza

Publikováno v: Cruz-cabeza, A J, Taylor, E, Sugden, I J, Bowskill, D H, Wright, S E, Abdullahi, H, Tulegenov, D, Sadiq, G & Davey, R J 2020, ' Can solvated intermediates inform us about nucleation pathways? The case of β-pABA ', CrystEngComm . https://doi.org/10.1039/D0CE00970A, https://doi.org/10.1039/d0ce00970a
Wright, S 2020, ' Can solvated intermediates inform us about nucleation pathways? The case of β-pABA ', CrystEngComm . https://doi.org/10.1039/d0ce00970a

Classical nucleation theory teaches the idea that molecular clusters form and grow in solution and that depending on prevailing conditions there is a chance for some to grow large enough to overcome the interfacial energy penalty and become mature cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee3ca70447cb6baa9b3229233baa5fd
http://hdl.handle.net/10044/1/84540

When Therapy might be Needed

Autor: Sarah E. Wright

Publikováno v: Redefining Trauma ISBN: 9780429269110

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89a1be6861d874cb4de626ae79b58ce3
https://doi.org/10.4324/9780429269110-15