Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sarah E Sullivan"'
Autor:
Augustine N. Vu, Santana P. Garcia, Jenny H. Tran, Adrian A. Godoy, Joaquin M. Mesa, Cassidy M. DiTirro, Kinsey L. Kotsch, Sarah E. Sullivan, Vincent J. Tavalez, Kateri A. Ahrendt
Publikováno v:
Journal of Chemical Education. 100:914-920
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e0fd16ce3bbdc505a1be2d30de66682
https://doi.org/10.1021/acs.jchemed.2c01097
https://doi.org/10.1021/acs.jchemed.2c01097
Publikováno v:
Cell and Gene Therapy Insights. 5:455-463
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d8bf67c2291194d29fef28913251757
https://doi.org/10.18609/cgti.2019.050
https://doi.org/10.18609/cgti.2019.050
Autor:
Alexander Meissner, Andreas R. Pfenning, Philip L. De Jager, Tracy L. Young-Pearse, David A. Bennett, Jishu Xu, Cristin McCabe, Elizabeta Gjoneska, Hans-Ulrich Klein, Julie A. Schneider, Anna Tang, Bradley E. Bernstein, Robert V. Smith, Li-Huei Tsai, Sara Mostafavi, Sarah E. Sullivan, Belinda J. Kaskow
Publikováno v:
Nature neuroscience
Nature Neuroscience
Nature Neuroscience
Accumulation of tau and amyloid-β are two pathologic hallmarks of Alzheimer’s disease (AD). We conducted an epigenome-wide association study using the H3K9 acetylation (H3K9ac) mark in 669 aged human prefrontal cortices: in contrast to amyloid-β,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e699f60e53102cfc147beb23c6ae66
http://europepmc.org/articles/PMC6516529
http://europepmc.org/articles/PMC6516529
Autor:
Jun Hao, Dong Lin, Colin Collins, Xinpei Ci, Xin Dong, Hui Xue, Stephen Yiu Chuen Choi, Anne Haegert, Sarah E Sullivan, Yong Wang, Yuzhuo Wang, Rebecca Wu
Publikováno v:
International journal of cancerREFERENCES. 148(2)
Prostate cancer (PCa) progression is driven by androgen receptor (AR) signaling. Unfortunately, androgen-deprivation therapy and the use of even more potent AR pathway inhibitors (ARPIs) cannot bring about a cure. ARPI resistance (ie, castration-resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056d95613a9e68d98f6a581f8587068a
https://pubmed.ncbi.nlm.nih.gov/33038264
https://pubmed.ncbi.nlm.nih.gov/33038264
Autor:
Sarah E. Sullivan, Mariko Taga, Tracy L. Young-Pearse, Valentina N. Lagomarsino, Philip L. De Jager, Jishu Xu, Mei-Chen Liao, Robert V. Smith, David A. Bennett, Charles C. White
Publikováno v:
Human Molecular Genetics. 28:718-735
Large-scale ‘omic’ studies investigating the pathophysiological processes that lead to Alzheimer's disease (AD) dementia have identified an increasing number of susceptibility genes, many of which are poorly characterized and have not previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c6b50b5a7c163d074b71281055c440
https://doi.org/10.1093/hmg/ddy376
https://doi.org/10.1093/hmg/ddy376
Autor:
Lei Yu, Lori B. Chibnik, Tracy L. Young-Pearse, Julie A. Schneider, Robert V. Smith, Sarah E. Sullivan, Philip L. De Jager, Aviv Regev, David A. Bennett, Jishu Xu, David E. Root, Sara Mostafavi, Cristin McCabe, Ellis Patrick, Mariko Taga, Elizabeth M. Bradshaw, Shinya Tasaki, Chris Gaiteri, Hans-Ulrich Klein, Vitalina Komashko, Charles C. White
Publikováno v:
Nature neuroscience
There is a need for new therapeutic targets with which to prevent Alzheimer’s disease (AD), a major contributor to aging-related cognitive decline. Here, we report the construction and validation of a molecular network of the aging human frontal co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadec1e1dc11bdb004f9c2ecce294822
http://europepmc.org/articles/PMC6599633
http://europepmc.org/articles/PMC6599633
Autor:
Julie A. Schneider, Cristin McCabe, Anna Tang, Bradley E. Bernstein, Robert V. Smith, Sarah E. Sullivan, Li-Huei Tsai, Tracy L. Young-Pearse, Alexander Meissner, Andreas R. Pfenning, Elizabeta Gjoneska, Sara Mostafavi, David A. Bennett, Philip L. De Jager, Hans-Ulrich Klein, Jishu Xu, Belinda J. Kaskow
SummaryAccumulation of tau and amyloid-β are two pathologic hallmarks of Alzheimer’s disease (AD). Here, we conducted an epigenome-wide association study using the H3K9 acetylation (H3K9Ac) mark in 669 aged human prefrontal cortices: in contrast t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5e8ca1d943e09914d129ab63de3d12
Autor:
Elizabeth M. Bradshaw, Lori B. Chibnik, Tracy L. Young-Pearse, Philip L. De Jager, Sara Mostafavi, Jishu Xu, Aviv Regev, Sarah E. Sullivan, Lei Yu, Mariko Taga, Julie A. Schneider, Robert V. Smith, Charles C. White, Vitalina Komashko, David A. Bennett, David E. Root, Hans-Ulrich Klein, Shinya Tasaki, Chris Gaiteri, Ellis Patrick, Cristin McCabe
The fact that only symptomatic therapies of small effect are available for Alzheimer’s disease (AD) today highlights the need for new therapeutic targets with which to prevent a major contributor to aging-related cognitive decline. Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8755c3f0ad9b707b4ff7e3bfc34117
https://doi.org/10.1101/205807
https://doi.org/10.1101/205807
Publikováno v:
Journal of Biological Chemistry. 289:15374-15383
Aberrant amyloid β (Aβ) production plays a causal role in Alzheimer disease pathogenesis. A major cellular pathway for Aβ generation is the activity-dependent endocytosis and proteolytic cleavage of the amyloid precursor protein (APP). However, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9592200ff19ffcb3df12231094f57bb8
https://doi.org/10.1074/jbc.m113.541003
https://doi.org/10.1074/jbc.m113.541003
Autor:
Sarah E. Sullivan, Sara Mostafavi, Tracy Pearse, David A. Bennett, Philip L. De Jager, Charles L. White, Chris Gaiteri
Publikováno v:
Alzheimer's & Dementia. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cf0d57a01851bdf4727c1ad23eb59c9
https://doi.org/10.1016/j.jalz.2016.06.381
https://doi.org/10.1016/j.jalz.2016.06.381