Zobrazeno 1 - 10
of 511
pro vyhledávání: '"Sarah E Pinder"'
Autor:
Maartje vanSeijen, Katarzyna Jóźwiak, Sarah E Pinder, Allison Hall, Savitri Krishnamurthy, Jeremy SJ Thomas, Laura C Collins, Jonathan Bijron, Joost Bart, Danielle Cohen, Wen Ng, Ihssane Bouybayoune, Hilary Stobart, Jan Hudecek, Michael Schaapveld, Alastair Thompson, Esther H Lips, Jelle Wesseling, The Grand Challenge PRECISION consortium.
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 3, Pp 233-242 (2021)
Abstract The prognostic value of cytonuclear grade in ductal carcinoma in situ (DCIS) is debated, partly due to high interobserver variability and the use of multiple guidelines. The aim of this study was to evaluate interobserver agreement in gradin
Externí odkaz:
https://doaj.org/article/018d235b3e01461b8b9e9bd581a263c5
Autor:
Robert C Stein, Janet A Dunn, John MS Bartlett, Amy F Campbell, Andrea Marshall, Peter Hall, Leila Rooshenas, Adrienne Morgan, Christopher Poole, Sarah E Pinder, David A Cameron, Nigel Stallard, Jenny L Donovan, Christopher McCabe, Luke Hughes-Davies, Andreas Makris, on behalf of the OPTIMA Trial Management Group
Publikováno v:
Health Technology Assessment, Vol 20, Iss 10 (2016)
Background: There is uncertainty about the chemotherapy sensitivity of some oestrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancers. Multiparameter assays that measure the expression of several tumour
Externí odkaz:
https://doaj.org/article/577852a5b41847748a6b9015ea7410ba
Autor:
Iain D. Lyburn, Robert Scott, Eleanor Cornford, Pascaline Bouzy, Nicholas Stone, Charlene Greenwood, Ihsanne Bouybayoune, Sarah E. Pinder, Keith Rogers
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27686- (2024)
Rationale and objectives: The potential of breast microcalcification chemistry to provide clinically valuable intelligence is being increasingly studied. However, acquisition of crystallographic details has, to date, been limited to high brightness,
Externí odkaz:
https://doaj.org/article/39581af5426a4809bc943cab839807a9
Autor:
Sarah B. Gosling, Emily L. Arnold, Samantha K. Davies, Hannah Cross, Ihssane Bouybayoune, Doriana Calabrese, Jayakrupakar Nallala, Sarah E. Pinder, Liping Fu, Esther H. Lips, Lorraine King, Jeffrey Marks, Allison Hall, Lars J. Grimm, Thomas Lynch, Donna Pinto, Hilary Stobart, E. Shelley Hwang, Jelle Wesseling, Kalotina Geraki, Nicholas Stone, Iain D. Lyburn, Charlene Greenwood, Keith D. Rogers, Grand Challenge PRECISION Consortium
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Ductal carcinoma in-situ (DCIS) accounts for 20–25% of all new breast cancer diagnoses. DCIS has an uncertain risk of progression to invasive breast cancer and a lack of predictive biomarkers may result in relatively high levels (~ 75%) of
Externí odkaz:
https://doaj.org/article/0c736cfe79ab4053ba3ef0858002ace5
Autor:
Alejandro Martinez Chibly, Alice Shia, Radia Johnson, Michael S. Hwang, Marc Hafner, Ciara Metcalfe, Kalpit Shah, Michal Slyper, Chris Bolen, Sarah E. Pinder, Alastair M. Thompson, Steven Gendreau, Peter Schmid
Publikováno v:
Cancer Research. 83:PD10-06
Background: Endocrine therapy (ET) is the mainstay of ER+ BC treatment. However; up to 20% of ER+ BC tumors progress into metastatic disease and develop ET resistance, underscoring the need for combination therapies. Preclinical data suggest that com
Autor:
Stuart A. McIntosh, Charlotte E. Coles, David Dodwell, Kenneth Elder, Jessica Foster, Claire Gaunt, Amanda Kirkham, Iain Lyburn, Jenna Morgan, Sangeetha Paramasivan, Sarah E. Pinder, Sarah Pirrie, Shelley Potter, Tracy Roberts, Nisha Sharma, Hilary Stobart, Elizabeth Southgate, Sian Taylor-Phillips, Matthew Wallis, Daniel Rea
Publikováno v:
Cancer Research. 83:OT3-20
Background: Mammographic screening programmes reduce breast cancer mortality, but detect many small tumours with favourable biological features which may not progress during a woman’s lifetime. Screen-detected cancers are treated with standard surg
Autor:
Ayaka Katayama, Jane Starczynski, Michael S Toss, Abeer M Shaaban, Elena Provenzano, Cecily M Quinn, Grace Callagy, Colin A Purdie, Rebecca Millican‐Slater, David Purnell, Leena Chagla, Tetsunari Oyama, Sarah E Pinder, Steve Chan, Ian Ellis, Andrew H S Lee, Emad A Rakha
Publikováno v:
Histopathology. 81:511-519
Chromosome 17 alterations affect the assessment of HER2 gene amplification in breast cancer (BC), but its clinical significance remains unclear. This study aimed to identify the prevalence of centromere enumeration probe 17 (CEP17) alterations, and i
Autor:
Gregory Verghese, Mengyuan Li, Fangfang Liu, Amit Lohan, Nikhil Cherian Kurian, Swati Meena, Patrycja Gazinska, Aekta Shah, Aasiyah Oozeer, Terry Chan, Mark Opdam, Sabine Linn, Cheryl Gillett, Elena Alberts, Thomas Hardiman, Samantha Jones, Selvam Thavaraj, J Louise Jones, Roberto Salgado, Sarah E Pinder, Swapnil Rane, Amit Sethi, Anita Grigoriadis
Publikováno v:
The Journal of Pathology.
Autor:
Tony Ng, Andrew N.J. Tutt, Paul Ellis, Sergio A. Quezada, Borivoj Vojnovic, Peter Lane, David R. Withers, Uzma Hasan, Leo M. Carlin, Frank McCaughan, Simon Ameer-Beg, Simon P. Poland, Cheryl E. Gillett, Sarah E. Pinder, Stewart G. Martin, Julie Owen, Manuel Rodriguez-Justo, Dominic Patel, Natalie Woodman, Paul R. Barber, Gilbert O. Fruhwirth, Anita Grigoriadis, Felix Wong, Farzana Noor, Patrycja Gazinska, Anthony Cheung, Peter Gordon, Victoria Male, Rachel Evans, James Monypenny, Katherine Lawler, Fabian Flores-Borja, Sheeba Irshad
Cancer cells tend to metastasize first to tumor-draining lymph nodes, but the mechanisms mediating cancer cell invasion into the lymphatic vasculature remain little understood. Here, we show that in the human breast tumor microenvironment (TME), the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17cbad6af0fb559eaeb880531f752848
https://doi.org/10.1158/0008-5472.c.6509700.v1
https://doi.org/10.1158/0008-5472.c.6509700.v1
Autor:
Tony Ng, Andrew N.J. Tutt, Paul Ellis, Sergio A. Quezada, Borivoj Vojnovic, Peter Lane, David R. Withers, Uzma Hasan, Leo M. Carlin, Frank McCaughan, Simon Ameer-Beg, Simon P. Poland, Cheryl E. Gillett, Sarah E. Pinder, Stewart G. Martin, Julie Owen, Manuel Rodriguez-Justo, Dominic Patel, Natalie Woodman, Paul R. Barber, Gilbert O. Fruhwirth, Anita Grigoriadis, Felix Wong, Farzana Noor, Patrycja Gazinska, Anthony Cheung, Peter Gordon, Victoria Male, Rachel Evans, James Monypenny, Katherine Lawler, Fabian Flores-Borja, Sheeba Irshad
Supplementary Methods described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71451bab18944309659219ef275894e1
https://doi.org/10.1158/0008-5472.22416972
https://doi.org/10.1158/0008-5472.22416972