Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Sarah E Panzer"'
Autor:
Natalie M Bath, Xiang Ding, Nancy A Wilson, Bret M Verhoven, Brittney A Boldt, Adarsh Sukhwal, Shannon R Reese, Sarah E Panzer, Arjang Djamali, Robert R Redfield
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211865 (2019)
Alloantibody represents a significant barrier in kidney transplant through the sensitization of patients prior to transplant through antibody mediated rejection (ABMR). APRIL BLyS are critical survival factors for mature B lymphocytes plasma cells, t
Externí odkaz:
https://doaj.org/article/029b107867da4ec9ba34a04f8fdd2243
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 7, Pp 581-586 (2022)
Objective Patients with lupus nephritis (LN) have a 26‐fold higher mortality rate compared with their peers. Kidney biopsy, the gold standard diagnostic method for LN, may have an average wait time of more than 50 days. Other gaps in quality proces
Externí odkaz:
https://doaj.org/article/a9288d2c173c43e9a21fde3c0a2cc0a9
Autor:
Sarah E. Panzer, Emily Joachim, Sandesh Parajuli, Weixiong Zhong, Brad C. Astor, Arjang Djamali
Publikováno v:
Kidney International Reports, Vol 4, Iss 4, Pp 582-593 (2019)
Introduction: Transplant glomerulopathy (TG) becomes increasingly prevalent in kidney transplant recipients over time, and it is strongly associated with allograft failure. To date, our prognostic biomarkers and understanding of the processes of immu
Externí odkaz:
https://doaj.org/article/9edb338a57ec4bc5adb0e5155dcea448
Autor:
Zijian Zhang, MD, Nancy A. Wilson, PhD, Raghavan Chinnadurai, PhD, Sarah E. Panzer, MD, Robert R. Redfield, III, MD, Shannon R. Reese, MS, Jacques Galipeau, MD, Arjang Djamali, MD
Publikováno v:
Transplantation Direct, Vol 4, Iss 9, p e387 (2018)
Background. We hypothesized that immunomodulatory properties of mesenchymal stromal cells (MSC) may be considered for desensitization. Methods. Autologous or allogeneic bone marrow derived MSC were infused via tail vein at 0.5 M (0.5 × 106), 1 M, or
Externí odkaz:
https://doaj.org/article/a7033284cd544c1e97cd70df9ace142d
Autor:
Robert R. Redfield, Shannon R. Reese, Sarah E. Panzer, Yabing Huang, Kenna R. Degner, Nancy A. Wilson, Lucille Ptak, Weixiong Zhong, Ding Xiang
Publikováno v:
Transplantation
BACKGROUND Transplant glomerulopathy (TG) is a pathological feature of chronic active antibody-mediated rejection (cAMR) and is associated with renal allograft failure. The specific role of B cells in the pathogenesis of TG is unclear. METHODS We use
Autor:
Sarah E. Panzer
Publikováno v:
Transplantation
Macrophages have emerged at the forefront of research in immunology and transplantation because of recent advances in basic science. New findings have illuminated macrophage populations not identified previously, expanded upon traditional macrophage
Autor:
William J. Burlingham, Bret M Verhoven, Sarah E. Panzer, Lei Shi, Robert R. Redfield, Weixiong Zhong, Xiang Ding, Shannon R. Reese, Arjang Djamali, Nancy A. Wilson, Loren C. Denlinger
Publikováno v:
Kidney360
Background: Extracellular adenosine triphosphate (ATP) binds to purinergic receptors and promotes inflammatory responses. We tested whether oxidized ATP (oATP), P2X7 receptor antagonist can attenuate acute kidney allograft rejection. Methods: Brown N
Autor:
Brandon Renner, V. Michael Holers, Andrew Feemster, Liudmila Kulik, Simon C. Satchell, Diana I. Jalal, Sarah E. Panzer, Paolo Cravedi, Chiara Cantarelli, Zhiying You, Cameron Lee, Jennifer Laskowski, Susan L Kalled, Weixiong Zhong, Samir M. Parikh, Fei Liu, Brad H. Rovin, Howard Trachtman, Joshua M. Thurman
Publikováno v:
Am J Physiol Renal Physiol
Focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) are common forms of idiopathic nephrotic syndrome. The causes of these diseases are incompletely understood, but the response of patients to immunosuppressive therapies sugges
Autor:
Maha Mohamed, Sarah E. Panzer, Sandesh Parajuli, Fahad Aziz, Brenda Muth, Weixiong Zhong, Brad C. Astor, Didier A. Mandelbrot, Arjang Djamali, Emily Joachim, Neetika Garg, Justin Blazel
Publikováno v:
World Journal of Transplantation
BACKGROUND The histopathological findings on the failing kidney allograft in the modern era is not well studied. In this study, we present our experience working with kidney transplant recipients with graft failure within one year of the biopsy. AIM
Autor:
Sarah E. Panzer, Brittney A. Boldt, Robert R Redfield rd, Adarsh Sukhwal, Weixiong Zhong, Xiang Ding, Natalie M. Bath, Nancy A. Wilson, Bret M Verhoven
Publikováno v:
Transplantation
BACKGROUND Highly sensitized candidates on the transplant waitlist remain a significant challenge, as current desensitization protocols have variable success rates of donor-specific antibody (DSA) reduction. Therefore, improved therapies are needed.