Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Sarah E Lutz"'
Autor:
Sarah E Lutz, Estibaliz González-Fernández, Juan Carlos Chara Ventura, Alberto Pérez-Samartín, Leonid Tarassishin, Hiromitsu Negoro, Naman K Patel, Sylvia O Suadicani, Sunhee C Lee, Carlos Matute, Eliana Scemes
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66657 (2013)
Pannexin1 (Panx1) is a plasma membrane channel permeable to relatively large molecules, such as ATP. In the central nervous system (CNS) Panx1 is found in neurons and glia and in the immune system in macrophages and T-cells. We tested the hypothesis
Externí odkaz:
https://doaj.org/article/bed2e29ae7374fc0a4cdf068daf6cc41
Autor:
Marcelo F Santiago, Jana Veliskova, Naman K Patel, Sarah E Lutz, Dorothee Caille, Anne Charollais, Paolo Meda, Eliana Scemes
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25178 (2011)
Imbalance of the excitatory neurotransmitter glutamate and of the inhibitory neurotransmitter GABA is one of several causes of seizures. ATP has also been implicated in epilepsy. However, little is known about the mechanisms involved in the release o
Externí odkaz:
https://doaj.org/article/7b0f6cc756ee4f15b455190f6469c735
Autor:
Ygor Marinho, Elizabeth S. Villarreal, Sammy Y. Aboagye, David L. Williams, Jun Sun, Claudia L. M. Silva, Sarah E. Lutz, Suellen D. Oliveira
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Schistosomiasis-associated Pulmonary Arterial Hypertension (Sch-PAH) is a life-threatening complication of chronic S. mansoni infection that can lead to heart failure and death. During PAH, the expansion of apoptosis-resistant endothelial cells (ECs)
Externí odkaz:
https://doaj.org/article/82466b06107d45c1b4e65f8c7c13f462
Autor:
Huiting Liao, Zimeng Cai, Haiqi Ye, QianLan Chen, Yan Zhang, Mehran Shaghaghi, Sarah E. Lutz, Weiwei Chen, Kejia Cai
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2023)
BackgroundConventional gadolinium (Gd)-enhanced MRI is currently used for stratifying the lesion activity of multiple sclerosis (MS) despite limited correlation with disability and disease activity. The stratification of MS lesion activity needs furt
Externí odkaz:
https://doaj.org/article/399ba97af9984fa28892b6722b449082
Autor:
Felecia M. Marottoli, Troy N. Trevino, Xue Geng, Zarema Arbieva, Pinal Kanabar, Mark Maienschein-Cline, James C. Lee, Sarah E. Lutz, Leon M. Tai
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Reports of APOE4-associated neurovascular dysfunction during aging and in neurodegenerative disorders has led to ongoing research to identify underlying mechanisms. In this study, we focused on whether the APOE genotype of brain endothelial cells mod
Externí odkaz:
https://doaj.org/article/9a7e56cd472340b895a41bd1b04ee7d1
Autor:
Ryan G. Lim, Chris Quan, Andrea M. Reyes-Ortiz, Sarah E. Lutz, Amanda J. Kedaigle, Theresa A. Gipson, Jie Wu, Gad D. Vatine, Jennifer Stocksdale, Malcolm S. Casale, Clive N. Svendsen, Ernest Fraenkel, David E. Housman, Dritan Agalliu, Leslie M. Thompson
Publikováno v:
Cell Reports, Vol 19, Iss 7, Pp 1365-1377 (2017)
Brain microvascular endothelial cells (BMECs) are an essential component of the blood-brain barrier (BBB) that shields the brain against toxins and immune cells. While BBB dysfunction exists in neurological disorders, including Huntington’s disease
Externí odkaz:
https://doaj.org/article/a4c8006ac0ea461986232304206450ef
Autor:
Troy N. Trevino, Ali A. Almousawi, Andrea Ochoa-Raya, Kait Zemanski, Suellen DS Oliveira, Felecia M. Marottoli, Leon M. Tai, Richard D. Minshall, Sarah E. Lutz
CXCL10 is an interferon-inducible chemokine that can recruit CXCR3+leukocytes to the central nervous system, leading to neuroinflammation, demyelination, and neuronal losses. How CXCL10 promotes leukocyte extravasation and diapedesis across the blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7db1ed23dee47a7eeb4d9108b423ec7a
https://doi.org/10.1101/2022.11.15.516689
https://doi.org/10.1101/2022.11.15.516689
Autor:
Troy N, Trevino, Sarah E, Lutz
Publikováno v:
Neuron. 110:1601-1603
How is the brain so efficient at excluding proteins, drugs, and immune cells from the blood? In this issue of Neuron, Ayloo et al. (2022) find that an extracellular matrix protein secreted by CNS pericytes shuts down endocytic transport in blood brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33b4f69e89dd4c4ec887c60c5250202
https://doi.org/10.1016/j.neuron.2022.04.011
https://doi.org/10.1016/j.neuron.2022.04.011
Autor:
Seshadri B. Niladhuri, Guliz O. Clare, KaReisha F. Robinson, Jacob Class, Ali A. Almousawi, Troy N. Trevino, Felecia M. Marottoli, Leon M. Tai, Justin Richner, Sarah E. Lutz
Persistent cognitive impairment and neuropsychiatric disorders are prevalent sequelae of SARS-CoV-2-induced COVID-19 in middle-aged adults. To model age-related neurological vulnerability to COVID-19, we induced respiratory SARS-CoV-2 MA10 infections
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::381bf291f508404a9c8a2db70f884674
https://doi.org/10.1101/2022.06.02.494552
https://doi.org/10.1101/2022.06.02.494552
Autor:
Suellen Darc Oliveira, Ejehi Erewele, Maricela Castellon, Andrew Schwartz, David L. Williams, Nick Morrell, Marcelo Bonini, Claudia L. M. Silva, Sarah E. Lutz, Serpil Erzurum, Richard D Minshall
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Introduction: Schistosomiasis-associated Pulmonary Arterial Hypertension (Sch-PAH) is a life-threatening complication of chronic S. mansoni infection, which can evolve to heart failure and death. During PAH, hyperproliferation of apoptosis-resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c665944a72b340d29b18dc78697f6cb
https://doi.org/10.1161/atvb.42.suppl_1.388
https://doi.org/10.1161/atvb.42.suppl_1.388