Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sarah E Little-Letsinger"'
Autor:
Sarah E Little-Letsinger
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0288212 (2023)
A reliable, widely available method to detect osteoporosis prior to fracture is needed. Serum levels of C-reactive protein may independently predict low bone mineral density (BMD) and high fracture risk. Existing empirical data focus on sexually and/
Externí odkaz:
https://doaj.org/article/b4c8dfbd0cfb4846b15d172bd8ad4683
Autor:
Cody McGrath, Sarah E. Little-Letsinger, Jeyantt Srinivas Sankaran, Buer Sen, Zhihui Xie, Martin A. Styner, Xiaopeng Zong, Weiqin Chen, Janet Rubin, Eric L. Klett, Rosalind A. Coleman, Maya Styner
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
Exercise, typically beneficial for skeletal health, has not yet been studied in lipodystrophy, a condition characterized by paucity of white adipose tissue, with eventual diabetes, and steatosis. We applied a mouse model of global deficiency of Bscl2
Externí odkaz:
https://doaj.org/article/90c8fb2686cb4275a153c4d436770c40
Autor:
Sarah E. Little-Letsinger, Ayland C. Letsinger, Jon P. Elizondo, Brianne M. Breidenbach, Harry A. Hogan, J. Timothy Lightfoot, Susan A. Bloomfield
Publikováno v:
Medicine & Science in Sports & Exercise.
Publikováno v:
Frontiers in Endocrinology. 14
The skeletal and immune systems are intricately intertwined within the bone marrow microenvironment, a field of study termed osteoimmunology. Osteoimmune interactions are key players in bone homeostasis and remodeling. Despite the critical role of th
Autor:
Clinton T. Rubin, Maya Styner, Eric L. Klett, Sarah E. Little-Letsinger, Gabriel M. Pagnotti, Cody McGrath, Janet Rubin, Brian O. Diekman
Publikováno v:
Seminars in Cell & Developmental Biology. 123:22-35
Aging induces alterations in bone structure and strength through a multitude of processes, exacerbating common aging- related diseases like osteoporosis and osteoarthritis. Cellular hallmarks of aging are examined, as related to bone and the marrow m
Autor:
AYLAND C. LETSINGER, FANG YANG, RANI MENON, SARAH E. LITTLE-LETSINGER, JORGE Z. GRANADOS, BRIANNE BREIDENBACH, ANJUSHREE R. IYER, TATIANA CASTRO PADOVANI, EDWARD C. NAGEL, ARUL JAYARAMAN, J. TIMOTHY LIGHTFOOT
Publikováno v:
Medicine and science in sports and exercise. 54(9)
Chronic overfeeding via a high-fat/high-sugar (HFHS) diet decreases wheel running and substantially alters the gut metabolome of C57BL/6J mice. In this study, we tested the hypothesis that fecal microbial transplants can modulate the effect of diet o
Publikováno v:
J Appl Physiol (1985)
Chronic inflammation leads to bone loss and fragility. Proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) consistently promote bone resorption. Dietary modulation of proinflammatory cytokines is an accepted therapeutic approach to
Autor:
Sarah E. Little-Letsinger, Zhihui Xie, Maya Styner, Cody McGrath, Amel Dudakovic, Janet Rubin, Buer Sen, Andre J. van Wijnen, Jeyantt S. Sankaran
Publikováno v:
JBMR Plus
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
JBMR Plus, Vol 5, Iss 3, Pp n/a-n/a (2021)
Use of the selective estrogen receptor modulator Tamoxifen (TAM) is a mainstay to induce conditional expression of Cre recombinase in transgenic laboratory mice. To excise β‐cateninfl/fl in 28‐day‐old male and female Prrx1‐CreER/β‐catenin
Autor:
Buer Sen, Janet Rubin, Amel Dudakovic, Cody McGrath, Zhihui Xie, Maya Styner, Sarah E. Little-Letsinger, Andre J. Wijnen, Jeyantt S. Sankaran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::113879552003d8b8b5b250c94503ebe8
https://doi.org/10.1002/jbm4.10450/v2/response1
https://doi.org/10.1002/jbm4.10450/v2/response1
Publikováno v:
Curr Osteoporos Rep
PURPOSE OF REVIEW: To highlight recent basic, translational, and clinical work demonstrating exercise and diet regulation of marrow adipose tissue (MAT) and bone, and how this informs current understanding of the relationship between marrow adiposity