Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Sarah E Keuss"'
Autor:
Thomas D Parker, David M Cash, Christopher A S Lane, Kirsty Lu, Ian B Malone, Jennifer M Nicholas, Sarah-Naomi James, Ashvini Keshavan, Heidi Murray-Smith, Andrew Wong, Sarah M Buchanan, Sarah E Keuss, Carole H Sudre, Marc Modat, David L Thomas, Sebastian J Crutch, Marcus Richards, Nick C Fox, Jonathan M Schott
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224030 (2019)
BackgroundThe human hippocampus comprises a number of interconnected histologically and functionally distinct subfields, which may be differentially influenced by cerebral pathology. Automated techniques are now available that estimate hippocampal su
Externí odkaz:
https://doaj.org/article/5aaf601528a24d96a94d9af0d24ba940
Autor:
Heidi Murray-Smith, Suzie Barker, Frederik Barkhof, Josephine Barnes, Thomas M. Brown, Gabriella Captur, Molly R.E.Cartlidge, David M. Cash, William Coath, Daniel Davis, John C. Dickson, James Groves, Alun D. Hughes, Sarah-Naomi James, Ashvini Keshavan, Sarah E. Keuss, Josh King-Robson, Kirsty Lu, Ian B. Malone, Jennifer M. Nicholas, Alicja Rapala, Catherine J. Scott, Rebecca Street, Carole H. Sudre, David L. Thomas, Andrew Wong, Selina Wray, Henrik Zetterberg, Nishi Chaturvedi, Nick C. Fox, Sebastian J. Crutch, Marcus Richards, Jonathan M. Schott
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-21 (2024)
Abstract Background Although age is the biggest known risk factor for dementia, there remains uncertainty about other factors over the life course that contribute to a person’s risk for cognitive decline later in life. Furthermore, the pathological
Externí odkaz:
https://doaj.org/article/9fdd7c07f6e74bf4bc709c0fc60fb7cd
Autor:
William Coath, Marc Modat, M. Jorge Cardoso, Pawel J. Markiewicz, Christopher A. Lane, Thomas D. Parker, Ashvini Keshavan, Sarah M. Buchanan, Sarah E. Keuss, Matthew J. Harris, Ninon Burgos, John Dickson, Anna Barnes, David L. Thomas, Daniel Beasley, Ian B. Malone, Andrew Wong, Kjell Erlandsson, Benjamin A. Thomas, Michael Schöll, Sebastien Ourselin, Marcus Richards, Nick C. Fox, Jonathan M. Schott, David M. Cash, for the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract INTRODUCTION The Centiloid scale aims to harmonize amyloid beta (Aβ) positron emission tomography (PET) measures across different analysis methods. As Centiloids were created using PET/computerized tomography (CT) data and are influenced by
Externí odkaz:
https://doaj.org/article/89fc878da77c45b0abc21824ecd8a625
Autor:
Sarah-Naomi James, Christopher A. Lane, Thomas D. Parker, Kirsty Lu, Jessica D. Collins, Heidi Murray-Smith, Michelle Byford, Andrew Wong, Ashvini Keshavan, Sarah Buchanan, Sarah E. Keuss, Diana Kuh, Nick C. Fox, Jonathan M. Schott, Marcus Richards
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-9 (2018)
Abstract Objective Identifying and recruiting people with early pre-symptomatic Alzheimer’s disease to neuroimaging research studies is increasingly important. The extent to which results of these studies can be generalised depends on the recruitme
Externí odkaz:
https://doaj.org/article/ba3b7ef34ae3429e973d5ecddf4dc1ef
Autor:
Sarah-Naomi James, Jennifer M. Nicholas, Kirsty Lu, Ashvini Keshavan, Christopher A. Lane, Thomas Parker, Sarah M. Buchanan, Sarah E. Keuss, Heidi Murray-Smith, Andrew Wong, David M. Cash, Ian B. Malone, Josephine Barnes, Carole H. Sudre, William Coath, Marc Modat, Sebastien Ourselin, Sebastian J. Crutch, Diana Kuh, Nick C. Fox, Jonathan M. Schott, Marcus Richards
Publikováno v:
Neurobiology of Aging, 122, 22-32. Elsevier Inc.
James, S-N, Nicholas, J M, Lu, K, Keshavan, A, Lane, C A, Parker, T, Buchanan, S M, Keuss, S E, Murray-Smith, H, Wong, A, Cash, D M, Malone, I B, Barnes, J, Sudre, C H, Coath, W, Modat, M, Ourselin, S, Crutch, S J, Kuh, D, Fox, N C, Schott, J M & Richards, M 2023, ' Adulthood cognitive trajectories over 26 years and brain health at 70 years of age : findings from the 1946 British Birth Cohort ', Neurobiology of Aging, vol. 122, pp. 22-32 . https://doi.org/10.1016/j.neurobiolaging.2022.10.003
James, S-N, Nicholas, J M, Lu, K, Keshavan, A, Lane, C A, Parker, T, Buchanan, S M, Keuss, S E, Murray-Smith, H, Wong, A, Cash, D M, Malone, I B, Barnes, J, Sudre, C H, Coath, W, Modat, M, Ourselin, S, Crutch, S J, Kuh, D, Fox, N C, Schott, J M & Richards, M 2023, ' Adulthood cognitive trajectories over 26 years and brain health at 70 years of age : findings from the 1946 British Birth Cohort ', Neurobiology of Aging, vol. 122, pp. 22-32 . https://doi.org/10.1016/j.neurobiolaging.2022.10.003
Few studies can address how adulthood cognitive trajectories relate to brain health in 70-year-olds. Participants (n = 468, 49% female) from the 1946 British birth cohort underwent 18F-Florbetapir PET/MRI. Cognitive function was measured in childhood
Autor:
Ashvini Keshavan, Henrietta Wellington, Zhongbo Chen, Ayesha Khatun, Miles Chapman, Melanie Hart, David M. Cash, William Coath, Thomas D. Parker, Sarah M. Buchanan, Sarah E. Keuss, Matthew J. Harris, Heidi Murray‐Smith, Amanda Heslegrave, Nick C. Fox, Henrik Zetterberg, Jonathan M Schott
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract INTRODUCTION We assessed the concordance of cerebrospinal fluid (CSF) amyloid beta (Aβ) and tau measured on the fully automated Lumipulse platform with pre‐symptomatic Alzheimer's disease (AD) pathology on amyloid positron emission tomogr
Externí odkaz:
https://doaj.org/article/6d192a34b4fb4435b96b930df6feef2f
Autor:
Aaron Z Wagen, William Coath, Ashvini Keshavan, Sarah-Naomi James, Thomas D Parker, Christopher A Lane, Sarah M Buchanan, Sarah E Keuss, Mathew Storey, Kirsty Lu, Amy Macdougall, Heidi Murray-Smith, Tamar Freiberger, David M Cash, Ian B Malone, Josephine Barnes, Carole H Sudre, Andrew Wong, Ivanna M Pavisic, Rebecca Street, Sebastian J Crutch, Valentina Escott-Price, Ganna Leonenko, Henrik Zetterberg, Henrietta Wellington, Amanda Heslegrave, Frederik Barkhof, Marcus Richards, Nick C Fox, James H Cole, Jonathan M Schott
Publikováno v:
The Lancet Healthy Longevity. 3:e607-e616
A neuroimaging-based biomarker termed the brain age is thought to reflect variability in the brain's ageing process and predict longevity. Using Insight 46, a unique narrow-age birth cohort, we aimed to examine potential drivers and correlates of bra
Autor:
Sarah E Keuss, David M Cash, Jennifer M Nicholas, Thomas D Parker, Christopher A Lane, Ashvini Keshavan, Sarah M Buchanan, Aaron Z Wagen, Mathew Storey, Matthew J Harris, Kirsty Lu, Sarah‐Naomi James, Rebecca E Street, Jo Barnes, Ian B Malone, Carole H Sudre, David L Thomas, John Dickson, Heidi Murray‐Smith, Tamar Freiberger, Andrew Wong, Sebastian J Crutch, Marcus Richards, Nick C Fox, Jonathan M Schott, William Coath
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Mar Estarellas Garcia, Alexandra L. Young, Sarah E Keuss, Daniel C. Alexander, Jonathan M Schott
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Sebastian J. Crutch, William Coath, Thomas D. Parker, Sarah M. Buchanan, Andrew Wong, Ashvini Keshavan, Jonathan M. Schott, Christopher A. Lane, Ivanna M. Pavisic, Kirsty Lu, Heidi Murray-Smith, Sarah E. Keuss, Nick C. Fox, David M. Cash, Sarah-Naomi James, Marcus Richards
Publikováno v:
Journal of Neurology, Neurosurgery, and Psychiatry
ObjectiveTo investigate subjective cognitive decline (SCD) in relation to β-amyloid pathology and to test for associations with anxiety, depression, objective cognition and family history of dementia in the Insight 46 study.MethodsCognitively unimpa